Mao Matsubayashi

Effectiveness and safety of tacrolimus versus infliximab as rescue therapy for intravenous corticosteroid-refractory acute severe ulcerative colitis: a multicenter cohort study

Takahito Katano, Shinji Okabayashi, Hajime Yamazaki, Mao Matsubayashi et autres

BACKGROUND & AIMS: Acute severe ulcerative colitis (ASUC) refractory to intravenous corticosteroids (IVCS) is a major clinical challenge with limited rescue therapy options. Although tacrolimus has been proposed as a potential rescue therapy, its effectiveness and safety compared with infliximab, widely used …

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Su1524 INTESTINAL ULTRASOUND ASSESSMENT OF MV-FLOW PREDICTS ENDOSCOPIC REMISSION IN ULCERATIVE COLITIS: THE FLOW TRIAL

Shunsuke Shibui, Shintaro Sagami, Yuichi Hasegawa, Nanako Inoue et autres

Su1524 INTESTINAL ULTRASOUND ASSESSMENT OF MV-FLOW PREDICTS ENDOSCOPIC REMISSION IN ULCERATIVE COLITIS: THE FLOW TRIAL

Shunsuke Shibui, Shintaro Sagami, Yuichi Hasegawa, Nanako Inoue et autres

P0887 Intestinal Ultrasound and Leucine-Rich α-2 Glycoprotein as Predicters of Relapse in Crohn’s Disease Patients with Normal CRP

Naoki Inoue, S Sagami, Moeko Komatsu, Kunio Asonuma et autres

Abstract Background Endoscopy is commonly used to assess disease activity in Crohn’s disease (CD), but it is invasive and limited to mucosal evaluation. We investigated whether intestinal ultrasound (IUS) and leucine-rich α-2 glycoprotein (LRG) can predict relapse in CD and support treat-to-target …

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First-line biologics as a treatment for ulcerative colitis: a multicenter randomized control study

Makoto Naganuma, Hisashi Shiga, Masayuki Shimoda, Minoru Matsuura et autres

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Antibiotic Susceptibility-Guided Concomitant Therapy Regimen with Vonoprazan, High-Dose Amoxicillin, Clarithromycin, and Metronidazole for Helicobacter pylori Eradication as Fourth-Line Regimen: An Interventional Study

Soichiro Sue, TAKESHI A. SATO, Mao Matsubayashi, Hiroaki Kaneko et autres

. We conducted this study as a fourth-line rescue regimen in Japan. METHODS: Twenty patients who underwent three rounds of eradication therapies (first- or second-line 7-day triple therapy consisting of amoxicillin and clarithromycin, or metronidazole- and sitafloxacin-based third-line therapy) and had failed …

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Clinical and histological impact of diffuse inflammation at pouchoscopy

Kenichiro Toritani, Hideaki Kimura, Koki Goto, Mao Matsubayashi et autres

PURPOSE: The anatomical location of inflammation in and around the ileal pouch affects the pouch survival rate, and diffuse inflammation has poor pouch survival rates. We aimed to clarify the symptoms and histological findings of diffuse inflammation of the pouch. METHODS: We …

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Massive bleeding and perforation due to post-colectomy pan-enteritis with a significant response to biologic in a patient with ulcerative colitis: a case report

Kenichiro Toritani, Hideaki Kimura, Manabu Maebashi, Kazuki Kurimura et autres

BACKGROUND: Post-colectomy pan-enteritis in ulcerative colitis (UC) is very rare, but it is often severe and fatal. We present a case of massive bleeding and perforation due to post-colectomy pan-enteritis, which showed a significant response to biologics in a UC patient. CASE …

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Intestinal ultrasound for intestinal Behçet disease reflects endoscopic activity and histopathological findings

Katsuki Yaguchi, Reiko Kunisaki, Sho Sato, Kaori Hirai et autres

BACKGROUND/AIMS: Intestinal Behçet disease is typically associated with ileocecal punched-out ulcers and significant morbidity and mortality. Intestinal ultrasound is a noninvasive imaging technique for disease monitoring. However, no previous reports have compared intestinal ultrasound with endoscopic ulcer activity or histopathological findings for …

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Clinical and histological impact of diffuse inflammation at pouchoscopy.

Kenichiro Toritani, Hideaki Kimura, Koki Goto, Mao Matsubayashi et autres

Abstract Background The anatomical location of inflammation in and around the ileal pouch affects the pouch survival rate, and diffuse inflammation have poor pouch survival rates. Aims We aimed to clarify the symptoms and histological findings of diffuse inflammation of the pouch. …

jp (code pays fourni par la source)

Immunomodulators after the discontinuation of anti‐tumor necrosis factor‐alpha antibody treatment and relapse in ulcerative colitis: A multicenter cohort study

Kunio Asonuma, Keiji Ozeki, Hajime Yamazaki, Shinji Okabayashi et autres

BACKGROUND AND AIM: Strategies to reduce relapse using immunomodulators (IMs) after discontinuing anti-tumor necrosis factor-alpha (TNF-α) antibody treatment are controversial in patients with ulcerative colitis (UC). In this study, we assessed the association between IMs after discontinuing anti-TNF-α antibody treatment and relapse …

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P183 Development of a new simple ultrasound activity score for intestinal Behçet's Disease

Katsuki Yaguchi, Reiko Kunisaki, Sumito Sato, Misato Izumi et autres

Abstract Background Intestinal Behçet's disease (BD) is a relapsing-remitting disease typically associated with punched-out ulcers in the ileocecal region. Optimal monitoring of disease activity is necessary; however, ileocolonoscopy cannot be performed on a regular basis as it is invasive, resource-intensive and causes …

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