James A. Stimson

Factors driving increases in Clostridioides difficile infection rates in England: a national case−control study, 2019 to 2024

Timothy Whiteley, André Charlett, Dimple Yasvin Chudasama, Zahin Amin‐Chowdhury et autres

BACKGROUND Numbers of Clostridioides difficile infections (CDI) in England have risen since 2021, but for unclear reasons. AIM This study’s objective was to understand factors driving CDI increases, and their relative impact. METHODS We conducted a case–control study in England from 2019/20 …

gb (code pays fourni par la source)

Factors driving increases in Clostridioides difficile infection rates in England: A national case-control study, 2019 to 2024

Timothy Whiteley, André Charlett, Dimple Yasvin Chudasama, Zahin Amin‐Chowdhury et autres

gb (code pays fourni par la source)

Modeling the impact of health care worker masking to reduce nosocomial SARS-CoV-2 transmission under varying adherence, prevalence, and transmission settings.

Timothy Whiteley, James A. Stimson, Colin Stewart Brown, Julie V. Robotham et autres

OBJECTIVES: To understand the scenarios where health care worker (HCW) masking is most impactful for preventing nosocomial transmission. METHODS: A mathematical agent-based model of nosocomial spread with masking interventions. Masking adherence, community prevalence, disease transmissibility, masking effectiveness, and proportion of breakroom (unmasked) …

us, gb (code pays fourni par la source)

Modelling the impact of healthcare worker masking to reduce nosocomial SARS-CoV-2 transmission under varying adherence, prevalence, and transmission settings.

Timothy Whiteley, James A. Stimson, Colin Stewart Brown, Julie V. Robotham et autres

gb (code pays fourni par la source)

Risk of unintended consequences from lower antibiotic prescribing for respiratory tract infections in primary care

James A. Stimson, Tricia M. McKeever, Emily Agnew, Wei Shen Lim et autres

OBJECTIVES: About 60% of antibiotic prescribing in primary care is for respiratory tract infections (RTIs), some of which is likely unnecessary. There is limited evidence on the association between reduced antibiotic prescribing and adverse events. We aimed to identify associations between practice-level …

gb (code pays fourni par la source)

Impact of interventions to reduce nosocomial transmission of SARS-CoV-2 in English NHS Trusts: a computational modelling study

Stephanie A. Evans, James A. Stimson, Diane Pople, Peter J White et autres

BACKGROUND: Prior to September 2021, 55,000-90,000 hospital inpatients in England were identified as having a potentially nosocomial SARS-CoV-2 infection. This includes cases that were likely missed due to pauci- or asymptomatic infection. Further, high numbers of healthcare workers (HCWs) are thought to …

gb (code pays fourni par la source)

The burden and dynamics of hospital-acquired SARS-CoV-2 in England

Ben Symons Cooper, Stephanie A. Evans, Yalda Jafari, Thi Mui Pham et autres

, but large-scale studies of its role in the SARS-CoV-2 pandemic are lacking. Such transmission risks spreading the virus to the most vulnerable individuals and can have wider-scale impacts through hospital-community interactions. Using data from acute hospitals in England, we quantify within-hospital …

kh, gb, th, nl, sg (code pays fourni par la source)

Evaluating the impact of testing strategies for the detection of nosocomial COVID-19 in English hospitals through data-driven modeling

Stephanie A. Evans, James A. Stimson, Diane Pople, Mark H. Wilcox et autres

Introduction: During the first wave of the COVID-19 pandemic 293,204 inpatients in England tested positive for SARS-CoV-2. It is estimated that 1% of these cases were hospital-associated using European centre for disease prevention and control (ECDC) and Public Health England (PHE) definitions. …

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Hospital onset SARS-CoV-2 infections in the Omicron wave: patterns of infection in the context of asymptomatic testing

James A. Stimson, Yingji Chen, Russell Hope, Julie V. Robotham et autres

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Estimation of the impact of hospital-onset SARS-CoV-2 infections on length of stay in English hospitals using causal inference

James A. Stimson, Koen Bernardus Pouwels, Russell Hope, Ben Symons Cooper et autres

BACKGROUND: From March 2020 through August 2021, 97,762 hospital-onset SARS-CoV-2 infections were detected in English hospitals. Resulting excess length of stay (LoS) created a potentially substantial health and economic burden for patients and the NHS, but we are currently unaware of any …

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The contribution of hospital-acquired infections to the COVID-19 epidemic in England in the first half of 2020

Gwenan M. Knight, Thi Mui Pham, James A. Stimson, Sebastian Funk et autres

BACKGROUND: SARS-CoV-2 is known to transmit in hospital settings, but the contribution of infections acquired in hospitals to the epidemic at a national scale is unknown. METHODS: We used comprehensive national English datasets to determine the number of COVID-19 patients with identified …

gb, nl, sg (code pays fourni par la source)

The contribution of hospital-acquired infections to the COVID-19 epidemic in England in the first half of 2020

Gwenan M. Knight, Thi Mui Pham, James A. Stimson, Sebastian Funk et autres

gb, us (code pays fourni par la source)