Side Gao

Atherogenic index of plasma as a predictor of cardiovascular outcomes in patients with myocardial infarction with nonobstructive coronary arteries

Side Gao, Sizhuang Huang, X Y Liu, Mengyue Yu et autres

Atherogenic index of plasma (AIP) has emerged as a novel marker of atherosclerosis and a predictor of outcomes in patients with coronary artery disease. However, the prognostic significance of AIP in a distinct population with myocardial infarction with nonobstructive coronary arteries (MINOCA) …

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Significance of Residual Inflammatory Risk and Persistent Inflammation in Patients with Myocardial Infarction with Nonobstructive Coronary Arteries

Side Gao, Sizhuang Huang, Xinming Liu, Mengyue Yu et autres

Background: Inflammation as assessed by high-sensitivity C-reactive protein (hs-CRP) predicts cardiovascular outcomes independently of low-density lipoprotein cholesterol (LDL-C) levels even in statin-treated patients with coronary artery disease. However, data regarding implications of residual inflammatory risk in patients with myocardial infarction with nonobstructive …

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The long-term prognostic value of the framingham risk scoring in patients with myocardial infarction with nonobstructive coronary arteries

Hao Zhang, Sizhuang Huang, Yanwen Fang, Side Gao et autres

Background The Framingham Risk Score for Cardiovascular Disease (FRSCVD), based on the Framingham Heart Study, serves as a foundation for many prediction models. However, its applicability in predicting the long-term prognosis of patients experiencing myocardial infarction with nonobstructive coronary arteries (MINOCA) remains …

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Impact of smoking cessation on cardiovascular outcomes in patients with myocardial infarction with nonobstructive coronary arteries

Side Gao, Sizhuang Huang, Xinming Liu, Mengyue Yu et autres

Background : Smoking is a preventable risk factor for incident cardiovascular disease. The impact of smoking status and potential benefits of smoking cessation in a distinct population with myocardial infarction with nonobstructive coronary arteries (MINOCA) remain poorly understood. Methods : In this …

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Metabolic syndrome severity score and long-term cardiovascular outcomes in patients with myocardial infarction with nonobstructive coronary arteries

Side Gao, Sizhuang Huang, Xinming Liu, Lin Yang Zhao

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Integrin β5 subunit regulates hyperglycemia-induced vascular endothelial cell apoptosis through FoxO1-mediated macroautophagy

Xuze Lin, Sizhuang Huang, Side Gao, Jinxing Liu et autres

BACKGROUND: Hyperglycemia frequently induces apoptosis in endothelial cells and ultimately contributes to microvascular dysfunction in patients with diabetes mellitus (DM). Previous research reported that the expression of integrins as well as their ligands was elevated in the diseased vessels of DM patients. …

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Prognostic implications of stress hyperglycemia ratio in patients with myocardial infarction with nonobstructive coronary arteries

Side Gao, Sizhuang Huang, Xuze Lin, Li Xu et autres

Background The role of stress hyperglycemia in acute myocardial infarction (AMI) has long been emphasized. Recently, the stress hyperglycemia ratio (SHR), a novel index reflecting an acute glycemia rise, has shown a good predictive value in AMI. However, its prognostic power in …

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Remnant Cholesterol Predicts Risk of Cardiovascular Events in Patients With Myocardial Infarction With Nonobstructive Coronary Arteries

Side Gao, Haobo Xu, Wenjian Ma, Jiansong Yuan et autres

Background Remnant cholesterol (RC) has been reported to promote atherosclerotic cardiovascular disease. Yet little is known regarding the RC‐related residual risk in patients with myocardial infarction (MI) with nonobstructive coronary arteries. Methods and Results A total of 1179 patients with MI with …

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Protective role of activating PPARγ in advanced glycation end products-induced impairment of coronary artery vasodilation via inhibiting p38 phosphorylation and reactive oxygen species production

Bing Hua, Qingbo Liu, Side Gao, Weiping Li et autres

Advanced glycation end products (AGEs) can damage voltage-gated K+ (Kv) channels and attenuate coronary artery vasodilation, but the underlying mechanisms remain unclear. The aim of this study was to investigate the role and potential mechanism of PPARγ in AGEs-induced Kv 1 channels …

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Real-World Use of Clopidogrel and Ticagrelor in Patients With Myocardial Infarction With Nonobstructive Coronary Arteries: Patient Characteristics and Long-Term Outcomes

Side Gao, Haobo Xu, Sizhuang Huang, Jiansong Yuan et autres

Background: Current guidelines recommend ticagrelor as the preferred P 2 Y 12 inhibitor on top of aspirin in patients after an acute coronary syndrome. Yet, the efficacy and safety of ticagrelor vs. clopidogrel in patients with myocardial infarction with nonobstructive coronary arteries …

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Hyperuricemia as a prognostic marker for long-term outcomes in patients with myocardial infarction with nonobstructive coronary arteries

Wenjian Ma, Side Gao, Sizhuang Huang, Jiansong Yuan et autres

BACKGROUND: Hyperuricemia (HUA) has been proved as a predictor of worse outcomes in patients with coronary artery disease. Here, we investigated the prognostic value of HUA in a distinct population with myocardial infarction with nonobstructive coronary arteries (MINOCA). METHODS: A total of …

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Impact of prediabetes on long-term cardiovascular outcomes in patients with myocardial infarction with nonobstructive coronary arteries

Side Gao, Wenjian Ma, Sizhuang Huang, Xuze Lin et autres

Abstract Background Abnormal glucose metabolism including diabetes (DM) and prediabetes (pre-DM) have been reported as predictors of poorer outcomes after acute myocardial infarction (AMI). However, the prognostic value of pre-DM in patients with myocardial infarction with nonobstructive coronary arteries (MINOCA) remains unclear. …

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