S.P. Wood

Novel Measurement of the Neutron Magnetic Form Factor from A=3 Mirror Nuclei

S. N. Santiesteban, S. Li, D. Abrams, S. Alsalmi et autres

The electromagnetic form factors of the proton and neutron encode information on the spatial structure of their charge and magnetization distributions. While measurements of the proton are relatively straightforward, the lack of a free neutron target makes measurements of the neutron's electromagnetic …

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A novel measurement of the neutron magnetic form factor from A=3 mirror nuclei

S. N. Santiesteban, S. Li, D. Abrams, S. Alsalmi et autres

The electromagnetic form factors of the proton and neutron encode information on the spatial structure of their charge and magnetization distributions. While measurements of the proton are relatively straightforward, the lack of a free neutron target makes measurements of the neutron's electromagnetic …

us, sa, hr, it, jp, ca, si, de, pr, am (code pays fourni par la source)

Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis Acta Crystallographica Section D Structural Biology

N.L. Mills-Davies, Danica S. Butler, Ed Norton, Damien Thompson et autres

A number of X-ray analyses of an enzyme involved in a key early stage of tetrapyrrole biosynthesis are reported. Two structures of human 5-aminolaevulinate dehydratase (ALAD), native and recombinant, have been determined at 2.8 Å resolution, showing that the enzyme adopts an …

Structure of a Kunitz-type potato cathepsin D inhibitor (vol 192, pg 554, 2015)

Jiao Guo, A.R. Coker, S.P. Wood, J.B. Cooper et autres

Structure of calexcitin-Gd3+ complex.

L. Chataigner, Jiyu Guo, P.T. Erskine, Alun R. Coker et autres

Endothiapepsin complexed with Phe-reduced-Tyr peptide.

Joshua Guo, J.B. Cooper, S.P. Wood

Search for Effects Beyond the Born Approximation in Polarization Transfer Observables in e→p Elastic Scattering

M. Meziane, E. J. Brash, R. Gilman, M. K. Jones et autres

Intensive theoretical and experimental efforts over the past decade have aimed at explaining the discrepancy between data for the proton electric to magnetic form factor ratio, ${G}_{E}/{G}_{M}$, obtained separately from cross section and polarization transfer measurements. One possible explanation for this difference …

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Targeting transthyretin: X-ray crystallography and rational drug design

Simon Erik Kolstoe, AJ Morrison, Alexander J. A. Cobb, Anthony G. Coyne et autres

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Drug targets for amyloidosis

SE Kolstoe, S.P. Wood

The amyloid hypothesis indicates that protein misfolding is at the root of many neurodegenerative disorders. Small molecules targeting the formation, clearance, aggregation to toxic oligomers or SOD (superoxide dismutase)-like activities of Abeta (amyloid beta-peptide) 1-42 have provided encouraging candidates for AD (Alzheimer's …

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Crystallisation and preliminary X-ray diffraction analysis of the protease from Southampton norovirus complexed with a Michael-acceptor inhibitor

R. J. Hussey, Leighton Coates, Raj Gill, Nick Wright et autres

Dodecahedral assembly of MhpD

Mark Montgomery, S.P. Wood

Human Transthyretin (TTR) complexed with a palindromic bivalent amyloid inhibitor (11 carbon linker).

Simon Erik Kolstoe, S.P. Wood, M.B. Pepys