Rosa Maria Esteves Arantes

Impact of Antarctic Expeditions on the Cytokine Profile in Humans: Evidence from an Integrative Review

Leonardo Pereira da Silva, Gustavo de Sá Oliveira Lima, Rosa Maria Esteves Arantes, Michele Macedo Moraes et autres

This is an integrative literature review aimed at investigating changes in the inflammatory profile, specifically regarding the production of pro- and anti-inflammatory cytokines in humans exposed to Antarctic expeditions.

Limosilactobacillus reuteri UN41 improves the survival rate and exhibits hepatoprotective effects in a murine model of Salmonella infection

Melina A. Cordeiro, Vivian C. Miranda, Katharina O. Barros, Paulo Henrique Fonseca do Carmo et autres

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Profile of inflammatory biomarkers in extreme conditions: Changes of serum amyloid A in a 7-week summer camp in Antarctica (Short Communication)

Michele Macedo Moraes, Leandro Borges, Thiago Teixeira Mendes, Elaine Hatanaka et autres

Isolated, confined, and extreme (ICE) conditions faced in Antarctica can influence immune system and inflammatory responses in humans. We evaluated the inflammatory biomarkers serum amyloid A (SAA), transforming growth factor-beta (TGF-β), and fatty acid-binding protein 2 (FABP2). Seven expeditioners took part in …

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Oral Treatment with Saccharomyces cerevisiae CNCM I-3856 Mitigates the Inflammatory Response Experimentally Induced by Salmonella enterica subsp. enterica Serovar Typhimurium in Mice

Lara L. Campos, Samantha Roberta Machado de Oliveira, Maisa N. S. Amaral, Bruno Gallotti et autres

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Analysis of dental care in Antarctic crews: Dental problems, case studies and treatments

Vojtěch Peřina, Julie Bartáková, A. Pires Freitas, Jan Máca et autres

Dental issues are relatively common in Antarctic stations both during short-term and long-term expeditions. In overwintering crews, dental problems may reach 10-15% of overall medical cases. In the expeditions working only during the austral summer season, the proportion of dental problems is …

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Long-term heat acclimation training in mice: Similar metabolic and running performance adaptations despite a lower absolute intensity than training at temperate conditions

Gustavo de Oliveira Zanetti, Pedro William Martins Pessoa, Tales Sambrano Vieira, Rodrigo de Almeida Garcia et autres

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Profile of interstitial cells of Cajal in a murine model of chagasic megacolon

Mayra Fernanda Ricci, Ana Lia Mazzeti, Joana Lobato Barbosa, Fabiana Simão Machado et autres

Disorders of gastrointestinal motility are the major physiologic problem in chagasic megacolon. The contraction mechanism is complex and controlled by different cell types such as enteric neurons, smooth muscle, telocytes, and an important pacemaker of the intestine, the interstitial cells of Cajal …

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Development of a membrane and a bilayer of chitosan, gelatin, and polyhydroxybutyrate to be used as wound dressing for the regeneration of rat excisional wounds

Joana Lobato Barbosa, Mariane Izabella Abreu de Melo, Pricila da Silva Cunha, Marcelo Coutinho de Miranda et autres

The skin is the largest organ in the human body that acts as a protective barrier from the outside environment. Certain dermatological pathologies or significant skin lesions can result in serious complications. Several studies have focused on the development of tissue-engineered skin …

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Sleep impairment and altered pattern of circadian biomarkers during a long-term Antarctic summer camp

Michele Macedo Moraes, Alice Lamounier Marques, Leandro Borges, Elaine Hatanaka et autres

Antarctic expeditions include isolation and exposure to cold and extreme photoperiods (with continuous natural light during summer) that may influence psychophysiological responses modulated by luminosity and sleep. We assessed changes in night sleep patterns by actigraphy, salivary biomarkers, and perceptual variables in …

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Cannabidiol Attenuates In Vivo Leukocyte Recruitment to the Spinal Cord Microvasculature at Peak Disease of Experimental Autoimmune Encephalomyelitis

Thiago Vitarelli da Silva, Danielle Bernardes, Onésia Cristina Oliveira‐Lima, Bárbara Fernandes Pinto et autres

Introduction: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system characterized by neuroinflammation leading to demyelination. The associated symptoms lead to a devastating decrease in quality of life. The cannabinoids and their derivatives have emerged as an encouraging …

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A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile

Michele Macedo Moraes, Thiago Teixeira Mendes, Leandro Borges, Alice Lamounier Marques et autres

Antarctic camps pose psychophysiological challenges related to isolated, confined, and extreme (ICE) conditions, including meals composed of sealed food. ICE conditions can influence the microbiome and inflammatory responses. Seven expeditioners took part in a 7-week Antarctic summer camp (Nelson Island) and were …

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Physical Activity, Seasonal Sensitivity and Psychological Well-Being of People of Different Age Groups Living in Extreme Environments

Caren Alvarado, Matías Castillo-Aguilar, Valeska Villegas, Claudia Estrada Goic et autres

Physical activity can prevent many organic and mental pathologies. For people living in extreme southern high-latitude environments, weather conditions can affect these activities, altering their psychological well-being and favoring the prevalence of seasonal sensitivity (SS). This study aims to determine the relationships …

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