Peng Xia

Corrigendum to ‘Wavelength-dependent photobiomodulation attenuates synovial inflammation in fibroblast-like synoviocytes and a collagenase-induced osteoarthritis model’ [Journal of Photochemistry & Photobiology B: Biology Volume 272 (2025) 113276]

Tianxiang Fan, Peng Xia, Safayet Ahmed, Yuen H. Tsang et autres

hk, us, cn (code pays fourni par la source)

Photobiomodulation for the treatment of knee osteoarthritis: therapeutic effects and molecular mechanism

Peng Xia, Tianxiang Fan, Yangxi Huang, Hanwen Zheng et autres

Knee osteoarthritis (KOA) is a common chronic and degenerative disease, particularly prevalent in the ageing population. The pathological features of KOA include articular cartilage degeneration, osteophyte formation, subchondral bone changes, and synovial hyperplasia. Photobiomodulation (PBM) involves the application of non-ionizing light sources …

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Abstract 4370048: Aging-Associated Lymphatic Dysfunction Drives Cardiac Injury During Chronic H1N1 Infection

Yanxi Shi, Ahlim Lee, Zihui Yang, Victoria I Cottrell et autres

Introduction: Viral respiratory infections (VRIs) are linked to cardiovascular complications that are more severe in the elderly, yet mechanistic understanding and therapeutic strategies remain limited. Hypothesis: We hypothesized that aging impairs lymphatic function, thereby exacerbating cardiac dysfunction following chronic influenza infection. Methods: …

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Wavelength-dependent photobiomodulation attenuates synovial inflammation in fibroblast-like synoviocytes and a collagenase-induced osteoarthritis model

Tianxiang Fan, Peng Xia, Safayet Ahmed, Zhi Yao et autres

hk, us, cn (code pays fourni par la source)

Abstract Or303: Activin Type IIA Receptor Inhibition Decreases Atrial Fibrillation Inducibility In Mice Via a Smurf1-Connexin43 Mechanism

Claire Castro, Aneesh Bapat, Ryan Hobson, Andy K. H. YU et autres

Introduction: Atrial fibrillation (AF) is a leading cause of stroke and heart failure. Recent genome-wide association studies have implicated ACVR2A , the gene encoding the Activin type IIA receptor (ActRIIA) in AF pathogenesis. The role of ActRIIA signaling in AF and its …

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Reversing Microglial Polarisation by High Intensity Interval Training: A Novel Approach to Mitigate Inflammatory Responses in Osteoarthritis via Jak2/Stat3 Pathway

Xinwei Wang, Mingxia Gao, Peng Xia, Ziqi Ye et autres

Osteoarthritis (OA) is associated with inflammatory responses linked to microglial polarisation within the central nervous system. However, exploring therapeutic approaches and their underlying mechanisms remains a direction for future research. The present study investigates the potential of high-intensity interval training (HIIT) to …

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Parameter-Optimized LED Therapy Targets IL-6/STAT3 Axis to Attenuate Tendinopathy via Dual Modulation of Inflammation and ECM Remodeling

Peng Xia, Tianxiang Fan, Xiaoju Wang, Ye Li et autres

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Venous Endothelial Cell Transcriptomic Profiling Implicates METAP1 in Preeclampsia

Maria Pabón, Robert M. Weisbrod, Claire Castro, Haobo Li et autres

BACKGROUND: Preeclampsia is a hypertensive disorder of pregnancy characterized by systemic endothelial dysfunction. The pathophysiology of preeclampsia remains incompletely understood. This study used human venous endothelial cell (EC) transcriptional profiling to investigate potential novel mechanisms underlying EC dysfunction in preeclampsia. METHODS: Venous …

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Reversing Microglial Polarization by High Intensity Interval Training: A Novel Approach to Mitigate Inflammatory Responses in Osteoarthritis via Jak2/Stat3 Pathway

Xinwei Wang, Mingxia Gao, Peng Xia, Ziqi Ye et autres

Osteoarthritis (OA) is associated with inflammatory responses linked to microglial polarization within the central nervous system. However, exploring therapeutic approaches and their underlying mechanisms remains a direction for future research. The present study investigates the potential of high-intensity interval training (HIIT) to …

cn, hk (code pays fourni par la source)

Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human

Jason D. Roh, Claire Castro, Andy Yu, Sarosh Rana et autres

Peripartum cardiomyopathy (PPCM) is an idiopathic form of pregnancy-induced heart failure associated with preeclampsia. Circulating factors in late pregnancy are thought to contribute to both diseases, suggesting a common underlying pathophysiological process. However, what drives this process remains unclear. Using serum proteomics, …

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High intensity interval training attenuates osteoarthritis-associated hyperalgesia in rats

Xinwei Wang, Jiulong Song, Peng Xia, Qiang Lin et autres

High-intensity interval training (HIIT) is a physical therapy that may benefit patients with osteoarthritis (OA). Cacna2d1 is a calcium channel subunit protein that plays an important role in the activity of nerve cells. However, there is currently no evidence on HIIT relieving …

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High-intensity interval training relieves osteoarthritis-induced neuropathic pain through promoting the polarization of M1 to M2 in microglia via the Jak2/Stat3 pathway in rats

xinwei Wang, Peng Xia, Qiang Lin, Kai Cheng et autres

Abstract Objective: Osteoarthritis (OA)-induced neuropathic pain is closely related to microglial polarization in the central nervous system. This study aimed to determine whether high-intensity interval training (HIIT) could relieve neuropathic pain and promote the polarization of M1 to M2 in microglia through …