Bruno Nunes

Sublethal toxicity of selenium nanoparticles in zebrafish early life stages: biochemical and behavioral responses

Pearl Ofoegbu, Rita Duarte, Soraia Almeida, Alexandre Marques et autres

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Integrating Ecotoxicity into Early-Stage Drug Development for Parasitic Diseases: A One Health Position Paper

Theo Zacharis, Sheraz Gul, Bruno Nunes, Paul M. Selzer et autres

Vector-borne parasitic diseases (VBDs), including leishmaniasis, trypanosomiases, schistosomiasis and babesiosis, pose an escalating threat to human and animal health across Europe and globally. Approximately 75% of emerging human infections originate from animals, and VBDs account for roughly 17% of the global infectious …

gr, de, pt, gb, es, be, us, it (code pays fourni par la source)

Integrating Ecotoxicity into Early-Stage Drug Development for Parasitic Diseases: A One Health Position Paper

Theo Zacharis, Sheraz Gul, Bruno Nunes, Paul M. Selzer et autres

Vector-borne parasitic diseases (VBDs), including leishmaniasis, trypanosomiases, schistosomiasis and babesiosis, pose an escalating threat to human and animal health across Europe and globally. Approximately 75% of emerging human infections originate from animals, and VBDs account for roughly 17% of the global infectious …

gr, de, pt, gb, es, be, us, it (code pays fourni par la source)

Acute toxicity of selenium nanoparticles to Daphnia magna, Danio rerio and Xenopus laevis

Victor Galhano, Ricardo J. B. Pinto, Ana Loureiro, Luís Afonso et autres

Selenium nanoparticles (SeNPs) are increasingly used in aquaculture and related sectors, raising concerns about their release and potential impact on aquatic organisms, especially during early life stages. This study assessed the acute toxicity of chemically synthesized surfactant-stabilized, non-functionalized SeNPs with a hydrodynamic …

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Effects of Commercially Available Plastics on Estuarine Sediment Dweller Polychaeta Hediste diversicolor

David Daniel, João Pinto da Costa, Ana V. Girão, Bruno Nunes

Microplastics (MPs) are a major contaminant in aquatic environments. Due to their size, they are likely to cause deleterious effects. In this study, we assessed the effects of MPs obtained from two commercially available plastics (PP and PET) in the polychaeta Hediste …

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Ecotoxicological Effects of Environmentally Relevant Concentrations of Nickel Nanoparticles on Aquatic Organisms from Three Trophic Levels: Insights from Oxidative Stress Biomarkers

Alberto Teodorico Correia, Eduardo Motta, David Daniel, Bruno Nunes et autres

This study investigated the ecotoxicological impacts of environmentally relevant concentrations (0.05, 0.50, and 5.00 mg/L) of nickel nanoparticles (Ni-NPs) by assessing oxidative stress biomarkers. The worm Hediste diversicolor, the bivalve Mytilus spp., and the fish Sparus aurata were chronically exposed to Ni-NPs …

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Bayesian optimization of a laser-plasma accelerator aiming the production of high-energy electron beams for VHEE radiotherapy

Bruno Nunes, Ricardo Elgul Samad, D. G. Nilson, Mirko Salomón Alva-Sánchez et autres

Radiation therapy aims to maximize tumor dose while minimizing exposure to healthy tissues. Despite advances, normal tissue toxicity remains a significant obstacle. While proton therapy shows promise, its high cost limits widespread adoption. Very high-energy electrons (VHEE, 50-250 MeV) represent an alternative …

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Low-power red laser and ultraviolet A LED irradiation reduces mRNA levels from telomere maintenance genes in Saccharomyces cerevisiae

Bruno Nunes, M. B.N. Oliveira, Flávio José da Silva Dantas, Adenilson de Souza da Fonseca

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Are lichens biocompasses? Revisiting an old prediction using new techniques

Bruno Nunes, Ana Braga, M. Marques, Iza Paula de Carvalho Lopes et autres

Abiotic factors influence not only vertical distributions of epiphytes, but also their radial positioning, such as around tree trunks. Due to planetary patterns of solar incidence, the equator-facing trunk portions receive direct sunlight, creating restrictive microclimatic conditions. Conversely, pole-facing portions remain shaded, …

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Characterization of PAHs in environmentally relevant concentrations of crude oil WAF and its effects on enzymatic biomarkers on Artemia parthenogenetica

Caio Alexandre de Freitas Schatzer, David Ferreira, Rafael André Lourenço, Inês Domingues et autres

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Low-power red laser and ultraviolet A LED irradiation alters mRNA levels from DNA repair genes in Saccharomyces cerevisiae

Bruno Nunes, Daphne Pinheiro, M. B.N. Oliveira, Bruno Ricardo Barreto Pires et autres

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Use of a fast toxicity test to determine whether carbendazim, fipronil, and sulfentrazone and their mixtures affect early zebrafish embryonic development

Sâmara da Silva Gomes, Bruno Nunes, Pabyton Gonçalves Cadena

Because of the exacerbated use of pesticides and their mixtures, and the difficulty of evaluating their toxicity, it is necessary to identify sensitive tools for the early detection of potential environmental risks related to the use of these chemicals. Our objective was …

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