Peter Irwin

Canine meningitis and meningoencephalitis in eastern Australia

Steven A. Reeves, Claire Gordon, Michelle Engelbrecht, Richard K. Burchell et autres

Meningoencephalitis is an important cause of neurological signs in dogs and may arise from infectious or noninfectious causes. In this retrospective study, dogs with steroid-responsive meningitis arteritis (SRMA), meningoencephalomyelitis of unknown origin (MUO), and eosinophilic meningoencephalomyelitis (EM), living on the east coast …

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From Local to Systemic: The Journey of Tick Bite Biomarkers in Australian Patients

Wenna Lee, Amanda Iasmim Alves Barbosa, Amy Huei‐Yi Lee, Andrew J Currie et autres

Tick bites and tick-related diseases are on the rise. Diagnostic tests that identify well-characterised tick-borne pathogens (TBPs) possess limited capacity to address the causation of symptoms associated with poorly characterised tick-related illnesses, such as debilitating symptom complexes attributed to ticks (DSCATT) in …

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Molecular analysis of human tick-bitten skin yields signatures associated with distinct spatial and temporal trajectories - A proof-of-concept study

Wenna Lee, Rym Ben-Othman, Patrycja Skut, Amy Huei‐Yi Lee et autres

Tick-associated diseases present challenges due to tridirectional interactions among host-specific responses, tick toxins and salivary proteins as well as microbes. We aimed to uncover molecular mechanisms in tick-bitten skin samples (cases) and contralateral skin samples (controls) collected simultaneously from the same participants, …

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Heartworm adulticide treatment: a tropical perspective

Filipe Dantas‐Torres, Jennifer K. Ketzis, Gabriela Pérez Tort, Andrei Daniel Mihalca et autres

Dirofilaria immitis (the canine heartworm) is widespread in the tropics, with prevalence surpassing 30% in high-risk areas. In addition to the suitable climatic conditions that favour mosquito abundance and filarial larva development, there is low compliance with the recommended year-round use of …

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An invasive human commensal and a native marsupial maintain tick populations at the urban fringe

Casey L. Taylor, Siobhon L. Egan, Alexander William Gofton, Peter Irwin et autres

Ticks (Acari: Ixodidae) are major disease vectors globally making it increasingly important to understand how altered vertebrate communities in urban areas shape tick population dynamics. In urban landscapes of Australia, little is known about which native and introduced small mammals maintain tick …

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The ‘other’ epidemic: canine ehrlichiosis in Australia

Peter Irwin, John William Beadle

Canine monocytic ehrlichiosis (Ehrlichia canis infection) is a serious tick-transmitted disease of dogs that was considered exotic to Australia until recently. The disease was first reported across northern and central Australia in 2020, with significant canine morbidity and mortalities observed at indigenous …

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A systems biology approach to better understand human tick-borne diseases

Wenna Lee, Amanda Iasmim Alves Barbosa, Peter Irwin, Andrew J Currie et autres

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Vector-borne and other pathogens of potential relevance disseminated by relocated cats

Ricardo Guillermo Maggi, Vicky Halls, Friederike Krämer, Michael R. Lappin et autres

Large populations of unowned cats constitute an animal welfare, ecological, societal and public health issue worldwide. Their relocation and homing are currently carried out in many parts of the world with the intention of relieving suffering and social problems, while contributing to …

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The Troublesome Ticks Research Protocol: Developing a Comprehensive, Multidiscipline Research Plan for Investigating Human Tick-Associated Disease in Australia

Amanda Iasmim Alves Barbosa, Michelle T. Long, Wenna Lee, Jill M. Austen et autres

In Australia, there is a paucity of data about the extent and impact of zoonotic tick-related illnesses. Even less is understood about a multifaceted illness referred to as Debilitating Symptom Complexes Attributed to Ticks (DSCATT). Here, we describe a research plan for …

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The bacterial biome of ticks and their wildlife hosts at the urban–wildland interface

Siobhon L. Egan, Casey L. Taylor, Peter Bruce Banks, Amy S. Northover et autres

Advances in sequencing technologies have revealed the complex and diverse microbial communities present in ticks (Ixodida). As obligate blood-feeding arthropods, ticks are responsible for a number of infectious diseases that can affect humans, livestock, domestic animals and wildlife. While cases of human …

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Protect your dog from this new deadly disease outbreak. We still don’t know how it got here

Peter Irwin, Charlotte L. Oskam, Amanda Iasmim Alves Barbosa

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A neurological presentation caused by brain metastases in a dog with interventricular septal hemangiosarcoma

T. L. Bunn, Cynthia Robveille, Peter Irwin, KFA Langner

BACKGROUND: Brain metastases are well known for disseminated hemangiosarcoma involving the right atrium/auricle. CASE REPORT: An 8-year-old male Australian Shepherd Dog presented with a 3-day history of circling to the left. A neurological examination revealed obtunded mentation, right hemi-inattention, bilateral strabismus towards …

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