Qiang Pan-Hammarstrom

The value of mucosal immunization against bacterial infections: will we conquer tuberculosis in the near future?

Diana Boraschi, Lázaro Moreira Marques Neto, Ling Chen, Luciana C. C. Leite et autres

These authors contributed equally 14 The Vaccine Immunology Network is a spontaneous network born in March 2024, aiming to strengthen the factual collaboration between academic research and industry in the vaccine field, which now includes over 100 participants from 9 countries.

br, cn, hk, se, it (code pays fourni par la source)

A single-cell co-expression score of MYC and BCL2 identifies high-risk BCR-addicted DLBCL benefiting from polatuzumab vedotin in the POLARIX trial

Shruti Sridhar, Will Harris, Chartsiam Tipgomut, Qiang Pan-Hammarstrom et autres

Abstract Introduction Double Expressor Lymphoma (DEL) refers to diffuse large B-cell lymphoma (DLBCL) with overexpression of the oncogenes MYC and BCL2 and carries a poor prognosis. However, the clinical utility of DEL is limited by variability in definitions for thresholds of positivity …

sg, us, se, cz, fr, de (code pays fourni par la source)

Spatial multi-omics reveal distinct immunosuppressive lipid-laden macrophages in primary CNS lymphoma compared to systemic DLBCL

Hong Liang, Min Liu, Shruti Sridhar, Charmaine Ong et autres

Abstract Introduction Primary central nervous system lymphoma (PCNSL) is an aggressive B-cell lymphoma exhibiting unique central nervous system (CNS) tropism, and high recurrence rates despite sharing morphological and molecular features with systemic Diffuse Large B-Cell Lymphoma (DLBCL). Given the unique immune landscape …

sg, cn, au, us, se, it (code pays fourni par la source)

Supplemental Materials from Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas

Ryan D. Morin, Sarit Assouline, Miguel Alcaide, Arezoo Mohajeri et autres

Supplemental methods Supplemental Figures Supplemental Figure S1. Overview of somatic copy number alterations in rrDLBCLs. Supplemental Figure S2. Consistent low coverage in the first exon of FOXO1. Supplemental Figure S3. Overview of FOXO1 mutations in rrDLBCLs. Supplemental Figure S4. VAFs corrected using …

Supplemental Table S6 from Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas

Ryan D. Morin, Sarit Assouline, Miguel Alcaide, Arezoo Mohajeri et autres

Targeted capture sequencing

Supplemental Table S4 from Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas

Ryan D. Morin, Sarit Assouline, Miguel Alcaide, Arezoo Mohajeri et autres

targeted sequencing results of rrDLBCL

Supplemental Table S3 from Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas

Ryan D. Morin, Sarit Assouline, Miguel Alcaide, Arezoo Mohajeri et autres

exome sequencing results of rrDLBCL

Supplemental Table S5 from Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas

Ryan D. Morin, Sarit Assouline, Miguel Alcaide, Arezoo Mohajeri et autres

Targeted sequencing of untreated DLBCL and TLy

Data from Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas

Ryan D. Morin, Sarit Assouline, Miguel Alcaide, Arezoo Mohajeri et autres

Abstract Purpose: Relapsed or refractory diffuse large B-cell lymphoma (rrDLBCL) is fatal in 90% of patients, and yet little is known about its biology. Experimental Design: Using exome sequencing, we characterized the mutation profiles of 38 rrDLBCL biopsies obtained at the time …

Data from Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas

Ryan D. Morin, Sarit Assouline, Miguel Alcaide, Arezoo Mohajeri et autres

Abstract Purpose: Relapsed or refractory diffuse large B-cell lymphoma (rrDLBCL) is fatal in 90% of patients, and yet little is known about its biology. Experimental Design: Using exome sequencing, we characterized the mutation profiles of 38 rrDLBCL biopsies obtained at the time …

Supplemental Table S3 from Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas

Ryan D. Morin, Sarit Assouline, Miguel Alcaide, Arezoo Mohajeri et autres

exome sequencing results of rrDLBCL

Supplemental Table S4 from Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas

Ryan D. Morin, Sarit Assouline, Miguel Alcaide, Arezoo Mohajeri et autres

targeted sequencing results of rrDLBCL