A.N.T.J. Kotte

Deep learning-enhanced image registration for accelerating daily adaptive magnetic resonance imaging-guided prostate radiotherapy

Cornel Zachiu, Gijsbert H. Bol, A.N.T.J. Kotte, T. Willigenburg et autres

Background and purpose Daily auto-contouring remains a workflow bottleneck in magnetic resonance-guided adaptive prostate radiotherapy (MRgRT). This study proposes and clinically validates a novel deep learning-enhanced deformable image registration (DIR) solution to accelerate this critical step. Materials and Methods A hybrid framework …

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1844 Dosimetric comparison of brachytherapy and MRLinac boost for locally advanced cervical cancer

Renske van Noortwijk, P.S. Kroon, K Ende, Jochem Hes et autres

Automated dose evaluation on daily cone-beam computed tomography for breast cancer patients

M. Groot Koerkamp, Peter R. S. Stijnman, Antonetta C. Houweling, Cornel Zachiu et autres

BACKGROUND AND PURPOSE: Our goal was to develop a workflow to automatically evaluate delivered dose on daily cone beam computed tomography (CBCT) in all breast cancer patients to assess dosimetric impact of anatomical changes and guide decision-making for offline plan adaptation. MATERIALS …

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2768: Patterns of failure: Recurrence location for head-and-neck cancer patients after radiotherapy

Cornelis P.J. Raaijmakers, Barbara Paic, A.N.T.J. Kotte, Patricia Doornaert et autres

Treatment robustness of total body irradiation with volumetric modulated arc therapy

Enrica Seravalli, Mirjam E. Willemsen-Bosman, A. Zoetelief, Sanne Roosenboom et autres

This study evaluated the robustness of multi-isocenter Volumetric Modulated Arc Therapy Total Body Irradiation dose distribution in the overlapping region between the head-first and feet-first computed tomography scans, considering the longitudinal isocenter shifts recorded during treatment delivery. For 15 out of 22 …

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Online adaptive MR-guided radiotherapy: Conformity of contour adaptation for prostate cancer, rectal cancer and lymph node oligometastases among radiation therapists and radiation oncologists

Marnix J. A. Rasing, G.G. Sikkes, Nicole G.P.M. Vissers, A.N.T.J. Kotte et autres

Background and purpose: Online adaptive MR-guided treatment planning workflows facilitate daily contour adaptation to the actual anatomy. Allocating contour adaptation to radiation therapists (RTTs) instead of radiation oncologists (ROs) might allow for increasing workflow efficiency. This study investigates conformity of adapted target …

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Impact of magnetic resonance-guided versus conventional radiotherapy workflows on organ at risk doses in stereotactic body radiotherapy for lymph node oligometastases

Anita M. Werensteijn-Honingh, P.S. Kroon, Dennis Winkel, J Gaál et autres

Background and purpose Magnetic resonance (MR)-linac delivery is expected to improve organ at risk (OAR) sparing. In this study, OAR doses were compared for online adaptive MR-linac treatments and conventional cone beam computed tomography (CBCT)-linac radiotherapy, taking into account differences in clinical …

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Comprehensive Quantitative Evaluation of Variability in Magnetic Resonance-Guided Delineation of Oropharyngeal Gross Tumor Volumes and High-Risk Clinical Target Volumes: An R-IDEAL Stage 0 Prospective Study

Carlos E. Cardenas, Sanne E. Blinde, Abdallah S. R. Mohamed, Sweet Ping Ng et autres

us, de, au, nl, ca, gb (code pays fourni par la source)

Comprehensive Quantitative Evaluation of Inter-observer Delineation Performance of MR-guided Delineation of Oropharyngeal Gross Tumor Volumes and High-risk Clinical Target Volumes: An R-IDEAL Stage 0 Prospective Study

Joint Head and Neck Radiotherapy-MRI Development Cooperative, Carlos E. Cardenas, Sanne E. Blinde, Sweet Ping Ng et autres

Purpose: Tumor and target volume manual delineation remains a challenging task in head and neck cancer radiotherapy. The purpose of this study is to conduct a multi-institutional evaluation of manual delineations of gross tumor volume (GTV), high-risk clinical target volume (CTV), parotids, …

us, de, au, nl, gb, Égypte, fr, ca (code pays fourni par la source)

Comparison of Library of Plans with two daily adaptive strategies for whole bladder radiotherapy

Duncan den Boer, M.D. den Hartogh, A.N.T.J. Kotte, Jochem R.N. van der Voort van Zyp et autres

Background and purpose Whole bladder radiotherapy is challenging due to inter- and intrafraction size and shape changes. To account for these changes, currently a Library of Plans (LoP) technique is often applied, but daily adaptive radiotherapy is also increasingly becoming available. The …

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An in-silico assessment of the dosimetric benefits of MR-guided radiotherapy for esophageal cancer patients

M. Boekhoff, Ingmar L. Defize, Alicia S. Borggreve, Richard van Hillegersberg et autres

PURPOSE: To assess the dosimetric benefits of online MR-guided radiotherapy (MRgRT) for esophageal cancer patients and to assess how these benefits could be translated into a local boosting strategy to improve future outcomes. METHODS: Twenty-nine patients were in-silico treated with both a …

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CTV-to-PTV margin assessment for esophageal cancer radiotherapy based on an accumulated dose analysis

M. Boekhoff, Ingmar L. Defize, Alicia S. Borggreve, Richard van Hillegersberg et autres

PURPOSE: This study aimed to assess the smallest clinical target volume (CTV) to planned target volume (PTV) margins for esophageal cancer radiotherapy using daily online registration to the bony anatomy that yield full dosimetric coverage over the course of treatment. METHODS: 29 …

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