Oliver Felthaus

Targeting Aromatase and 5-α-Reductase to Limit Dysfunctional Adipogenesis in Multiple Symmetric Lipomatosis

Gabriella Milan, Chiara Compagnin, Isabel Zucal, Giuseppe Perale et autres

Background: Multiple symmetric lipomatosis (MSL) is an orphan disease characterized by pathological expansion of lipomatous tissue (LT) in the subcutaneous adipose tissue (SAT) areas, causing severe deformities and compression of vital organs. To date, the only treatment options available are either lifestyle …

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Regenerative Potential of Autologously Processed White Adipose Tissue for Peripheral Nerve Regeneration: Evaluation of Growth Factor Profiles and Electrical Stimulation

Tobias Egger, Andreas Eigenberger, Oliver Felthaus, Marc Ruewe et autres

Peripheral nerve injuries (PNI) present a major clinical and socioeconomic challenge due to limited regenerative capacity. Adipose-derived stem cells (ADSCs) within the stromal vascular fraction (SVF) of white adipose tissue offer a promising autologous source for regenerative support. This study evaluated the …

Regenerative Potential of Autologously Processed White Adipose Tissue for Peripheral Nerve Regeneration: Evaluation of Growth Factor Profiles and Electrical Stimulation

Tobias Egger, Andreas Eigenberger, Oliver Felthaus, Marc Ruewe et autres

Peripheral nerve injuries (PNI) present a major clinical and socioeconomic challenge due to limited regenerative capacity. Adipose-derived stem cells (ADSCs) within the stromal vascular fraction (SVF) of white adipose tissue offer a promising autologous source for regenerative support. This study evaluated the …

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Advancements in Breast Lipofilling: A 12-Year Retrospective Comparative Analysis of Patient Satisfaction and Complication Rates across Fat Preparation Methods

Rafael Loucas, Marios Loucas, Ronja Müller, Vanessa Brébant et autres

BACKGROUND: Breast lipofilling is a commonly utilized method in plastic surgery for breast reconstruction and augmentation. However, the procedure is often limited by the unpredictable survival of fat grafts, leading to dissatisfied patients and associated risks of complications. To address these challenges, …

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Physiological limits of syringe pressure during mechanical fat processing using a 10-mL syringe

Alexander Bartsch, Ludwig Schlegel, Andreas Eigenberger, Oliver Felthaus et autres

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Glycerol-Based Cryopreservation of CELT-Fat: Identification of the Optimal Concentration in a GMP-Compatible Protocol

Lukas Prantl, Oliver Felthaus, Andreas Eigenberger, Dmytro Oliinyk et autres

BACKGROUND: Autologous fat grafting is widely used in reconstructive, aesthetic and regenerative surgery and often requires repeated applications. Cryopreservation of lipoaspirate enables autologous fat banking and off-the-shelf availability; however, its clinical implementation is limited by freezing-induced tissue injury, regulatory requirements and uncertainties …

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Shaping mesenchymal stem cell fate with a two-dimensional covalent triazine framework for calmodulin modulation

Lei Wang, Boyu Zheng, Maryam Salahvarzi, Yi-An Yang et autres

Calmodulin (CaM) is a central calcium sensor and signaling hub that critically governs stem cell fate. However, directly intracellular modulation of CaM remains challenging due to its activity is tightly coupled to finely balanced calcium homeostasis, and conventional chemicals or biomaterials have …

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Current Evidence and Key Considerations in Choosing Harvesting Cannulas

Sally Kempa, Andreas Eigenberger, Oliver Felthaus, Lukas Prantl

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How Can I Evaluate the Quality and Relevance of Research on Fat Grafting for Practical Clinical Use?

Oliver Felthaus

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Level 1: CELT and CELTPLUS Protocols: A Standard Evidence-Based Guide for Fat Grafting

Lukas Prantl, Andreas Eigenberger, Sally Kempa, Konstantin Frank et autres

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Level 3: Advanced Essentials for Fat Grafting: A Comprehensive Guide for Specialists

Lukas Prantl, Andreas Eigenberger, Oliver Felthaus, Konstantin Frank et autres

From Lipoaspirate to Graft: A Guide to Separation Methods

Andreas Eigenberger, Sally Kempa, Oliver Felthaus, Lukas Prantl