Frank van Bockxmeer

Synopsis of an integrated guidance for enhancing the care of familial hypercholesterolaemia: an Australian perspective

Gerald F. Watts, David Sullivan, David L. Hare, Karam Kostner et autres

INTRODUCTION: Familial hypercholesterolaemia (FH) is a common, heritable and preventable cause of premature coronary artery disease, with significant potential for positive impact on public health and healthcare savings. New clinical practice recommendations are presented in an abridged guidance to assist practitioners in …

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Integrated Guidance for Enhancing the Care of Familial Hypercholesterolaemia in Australia

Gerald F. Watts, David Sullivan, David L. Hare, Karam Kostner et autres

Familial hypercholesterolaemia (FH) is a dominant and highly penetrant monogenic disorder present from birth that markedly elevates plasma low-density lipoprotein (LDL)-cholesterol concentration and, if untreated, leads to premature atherosclerosis and coronary artery disease (CAD). There are approximately 100,000 people with FH in …

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Gaps in the Care of Familial Hypercholesterolaemia in Australia: First Report From the National Registry

Jing Pang, David Sullivan, David L. Hare, David Colquhoun et autres

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B-vitamins and Depression

Andrew H. Ford, Osvaldo P. Almeida, Leon Flicker, Varsha Hirani et autres

B-vitamin insufficiency is associated with depression but it is uncertain if treatment with these is effective in prevention or treatment. 1. To determine if daily supplementation with B-vitamins enhances response to antidepressants. 2. Systematic review and meta-analysis of randomised, placebo-controlled trials of …

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The effect of a single nucleotide polymorphism of the CYP4F2 gene on blood pressure and 20-hydroxyeicosatetraenoic acid excretion after weight loss

Natalie C. Ward, Kevin D. Croft, Ian B. Puddey, Michael Phillips et autres

BACKGROUND: Genetic background partly determines the efficacy of interventions to lower blood pressure (BP). The CYP4F2 and CYP4A11 enzymes are renal 20-hydroxyeicosatetraenoic acid (20-HETE) synthases that regulate BP. Gene variants of CYP4F2 and CYP4A11 associate with hypertension and stroke. We showed that …

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Establishing an Australian and New Zealand Registry for Patients with Familial Hypercholesterolaemia

Ian Hamilton‐Craig, Gerald F. Watts, E. Hammond, David Sullivan et autres

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Using an Expert Computer System to Augment the Detection of Familial Hypercholesterolaemia in a Community Laboratory

Damon A. Bell, G. Edwards, Amanda J. Hooper, J. Alexander McMahon et autres

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WENDS-FH Morocco: The Wendish Emigration National Detection Study of FH Morocco in Familial Hypercholesterolaemia: Results of Cascade Family Screening

Ian Hamilton‐Craig, Frank van Bockxmeer, Fathima Kamil Faiz

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Impact of Telephoning the Requestors of Individuals Found to be at High Risk of Familial Hypercholesterolaemia

Damon A. Bell, Amanda J. Hooper, G. Edwards, L. Southwell et autres

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Impact of APOE e4 on the association of physical activity and cognition in older adults with memory complaints

Kay L. Cox, Leon Flicker, Osvaldo P. Almeida, Frank van Bockxmeer et autres

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Familial hypercholesterolaemia: a review with emphasis on evidence for treatment, new models of care and health economic evaluations

Gerald F. Watts, A. Juniper, Frank van Bockxmeer, Zanfina Ademi et autres

Familial hypercholesterolaemia (FH) is a condition that should be familiar to all health professionals involved in preventive medicine. FH is the most common and serious monogenic disorder of lipid metabolism that leads to premature coronary heart disease. However, most cases remain undetected …

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INTERIM Guidelines for the Diagnosis and Management of Familial Hypercholesterolaemia

David Sullivan, Ian Hamilton‐Craig, Frank van Bockxmeer, Gerald F. Watts

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