Christian Musahl

Largest documented cerebral aneurysm mimicking a giant brain tumor and treated by highly selective occlusion of inflow: illustrative case

Lukas Andereggen, Javier Añon, Angelo Tortora, Serge Marbacher et autres

BACKGROUND: Giant intracranial aneurysms (GIAs) are rare vascular lesions associated with significant morbidity and mortality. Their management is particularly challenging due to the absence of universal treatment guidelines, necessitating individualized strategies tailored to each case's unique morphology and hemodynamics. OBSERVATIONS: The authors …

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Targeted decompression to address long-standing anatomical distortion in a case of extensive, bilateral en plaque meningiomas: illustrative case

Stefanie Bauer, Karina Hofmann, Miriam Weiss, Christian Musahl et autres

BACKGROUND: Meningioma en plaque (MEP) is a rare subtype of meningioma with a carpet-like growth pattern, often causing hyperostosis. Even rarer is the presentation of bilateral MEP posing diagnostic and therapeutic challenges. Management of MEP usually entails early complete resection. Follow-up may …

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Effectiveness of 3D printed and mixed reality models in neurosurgical patient education: A systematic review

Stefanie Bauer, Joshua Haegler, Debora Cipriani, Markus Bruder et autres

Objective Neurosurgical patients often face psychological distress due to difficulty understanding their medical condition and treatment plan. Traditional educational tools like MRI or CT scans may not effectively convey this information. 3D-printed models and mixed reality (MR) devices have emerged as innovative …

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The impact of body-mass-index on functional outcomes and bleeding volumes in patients suffering spontaneous intracerebral haemorrhage

Stefan Wanderer, Attill Saemann, Basil Erwin Grüter, Julian Louis Muff et autres

Background and purpose The association between obesity and clinical as well as radiological outcomes in patients suffering spontaneous intracerebral haemorrhage (ICH) remains unclear. The obesity paradox suggests a protective effect regarding in-hospital mortality. This study evaluates the impact of body mass index …

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345 Planned interim analysis of PREOP-2 randomised trial (NCT05124236): low toxicity and high feasibility of preoperative SRS for brain metastases.

Susanne J. Rogers, Oliver Blanck, Olaf Wittenstein, Hajrullah Ahmeti et autres

The ATLAS/NOA-29 study protocol: a phase III randomized controlled trial of anterior temporal lobectomy versus gross-total resection in newly-diagnosed temporal lobe glioblastoma

Matthias B. Schneider, Anna‐Laura Potthoff, Yahya Ahmadipour, Valeri Borger et autres

BACKGROUND: The discovery of cellular tumor networks in glioblastoma, with routes of malignant communication extending far beyond the detectable tumor margins, has highlighted the potential of supramarginal resection strategies. Retrospective data suggest that these approaches may improve long-term disease control. However, their …

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Within five weeks: Rapidly grown glioblastoma discovered on repeat MRI after pathologic EEG

Zsuzsanna Szankai, Egle Huggenberger, Claudia Metzler‐Baddeley, Christian Musahl et autres

• Subtle EEG changes should prompt heightened awareness and consideration for repeating the EEG within a short period of time. • In the presence of recurrent seizures or new EEG changes, a repeat MRI is recommended, even if the previous MRI was …

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Characteristics and outcomes of men with erectile dysfunction as the presenting symptom due to a lactotroph adenoma

Lukas Andereggen, Angelo Tortora, Gerrit Alexander Schubert, Christian Musahl et autres

PURPOSE: Erectile dysfunction (ED) is frequently underreported in men suffering from prolactinomas and can be challenging to manage. Both dopamine agonists (DAs) and transsphenoidal surgery (TSS) correct hyperprolactinemia and restore gonadal function. However, there is scarce data regarding their effectiveness in correcting …

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Gender-specific prolactin thresholds to determine prolactinoma size: a novel Bayesian approach and its clinical utility

Markus Huber, Markus Martin Luedi, Gerrit Alexander Schubert, Christian Musahl et autres

Background: In clinical practice, the size of adenomas is crucial for guiding prolactinoma patients towards the most suitable initial treatment. Consequently, establishing guidelines for serum prolactin level thresholds to assess prolactinoma size is essential. However, the potential impact of gender differences in …

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Safety and functional outcome analysis of ventriculoperitoneal shunt placement for hydrocephalus within the critical phase of possible delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage

Julien Jost, Yasin Irmak, Basil Erwin Grüter, Angelo Tortora et autres

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The Impact of Body-Mass-Index on Functional Outcomes and Bleeding Volumes in Patients Suffering Non-Traumatic Intracerebral Haemorrhage

Stefan Wanderer, Attill Saemann, Basil Erwin Grüter, Sivani Sivanrupan et autres

The association between obesity and clinical as well as radiological outcomes in patients suffering non-traumatic intracerebral haemorrhage (ICH) remains unclear. The obesity paradox suggests a protective effect regarding in-hospital mortality. This study evaluates the impact of body mass index (BMI) on functional …

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Prolactinomas in adolescent and elderly patients—A comparative long-term analysis

Lukas Andereggen, Angelo Tortora, Gerrit Alexander Schubert, Christian Musahl et autres

Objectives Prolactinomas represent the most common type of secreting pituitary adenomas, yet are rarely encountered in adolescent-onset (AO; i.e. <18 years) or elderly-onset (EO; i.e. ≥65 years) cohorts. As a result, it is not clear whether long-term strategies should be focused differently …

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