Kathryn Nash

P104 An emulation trial testing the impact of pharmacist-led carvedilol dose titration in patients with clinically significant portal hypertension

Din He Tan, Yoon Jun Kim, Kathryn Nash, Salim I. Khakoo et autres

Introduction Carvedilol is known to reduce the incidence of decompensation in patients with liver cirrhosis and clinically significant portal hypertension (CSPH). Trials have shown that its benefits are achieved at high doses. In our experience patients can be inadequately dose titrated and …

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THU-159-YI Development and validation of dimethylarginines (DAS) as a novel biomarker to identify pre-ACLF and predict outcomes following acute decompensation of cirrhosis in two prospective multicentre european cohorts

Kohilan Gananandan, Peter Holland‐Fischer, Karen Louise Thomsen, Rohit Sawhney et autres

THU-519-YI Prescribing for pain and symptom management in hospital patients with advanced liver disease: a single centre, retrospective clinical audit

S. K. Phillips, Savitri Chandrasekaran, Yun Jung Kim, Kathryn Nash et autres

13 Prescribing for pain and symptom management in hospital patients with advanced liver disease: a single centre, retrospective clinical audit

Anita K Omasta-Martin, S. K. Phillips, Savitri Chandrasekaran, Yun Jung Kim et autres

Background and Aims Advanced liver disease patients require adjustments to dose of medications as per the British Association for the Study of the Liver (BASL) guidelines. In this study, we assessed whether prescribing adhered to BASL guidelines and if this changed following …

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P98 A pilot pharmacist led carvedilol titration service leads to sustained doses of high dose carvedilol in patients with clinically significant portal hypertension

Yun Jung Kim, Din He Tan, Kathryn Nash, Salim I. Khakoo et autres

Non-selective beta blockers (NSBBs) reduce the risk of hepatic decompensation in patients with cirrhosis and clinically significant portal hypertension (CSPH). However, prescribed doses in real-world practice are frequently below those used in clinical studies and sub-therapeutic doses risk beneficial effects not manifesting …

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THU-027-YI A pilot pharmacist led carvedilol titration service leads to sustained doses of high dose carvedilol in patients with clinically significant portal hypertension

Yun Jung Kim, Din He Tan, Kathryn Nash, Salim I. Khakoo et autres

Hepatitis C

Ryan Buchanan, Yun Jung Kim, Kathryn Nash

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Mapping of population disparities in the cholangiocarcinoma urinary metabolome

Munirah Alsaleh, Zoe Leftley, Thomas P. O’Connor, Thomas Hughes et autres

Phenotypic diversity in urinary metabolomes of different geographical populations has been recognized recently. In this study, urinary metabolic signatures from Western (United Kingdom) and South-East Asian (Thai) cholangiocarcinoma patients were characterized to understand spectral variability due to host carcinogenic processes and/or exogenous …

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Regional Responses to Conflict during the COVID-19 Pandemic

Kathryn Nash, Hannah den Boer

Regional Responses to COVID-19: The Role of Intergovernmental Organisations in Latin America, Africa, and the Middle East

Hannah den Boer, Kathryn Nash

There have been responses to the COVID-19 pandemic across multiple levels of governance from very local, community-based initiatives to international coordination by the WHO. While there has been significant analysis of the state-level and international level response, there has been less comprehensive …

The predictive value of MRI-based markers of liver disease on clinical outcomes in patients with cirrhosis

Christina Levick, Michael Pavlides, Emmanuel Selvaraj, Arjun Jayaswal et autres

PA-X Peace Agreements Database and Dataset, Version 4

Christine Bell, Sanja Badanjak, Juline Beaujouan, Tim Epple et autres

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