Marina Giovannini

MAGNESIUM DEPLETION SCORE IS ASSOCIATED WITH ARTERIAL STIFFNESS: DATA FROM THE BRISIGHELLA HEART STUDY

Arrigo Francesco Giuseppe Cicero, Federica Fogacci, Marina Giovannini, Elisa Grandi et autres

Randomized, Double-Blind, Crossover Trial Comparing Low-Glycemic Index Functional and Conventional Wholegrain Carbohydrates on Glycolipid Metabolism and Vascular Stress Markers in Adults with Suboptimal Triglyceridemia: The GLOW Study

Marina Giovannini, Federica Fogacci, Cristina Scollo, Valentina Di Micoli et autres

Mild fasting hypertriglyceridemia is often accompanied by early insulin resistance and atherogenic dyslipidemia, making it an attractive target for pragmatic dietary prevention. This trial aims to determine whether substituting common cereal-based staples with functional low-glycemic index (low-GI) products improves the triglyceride–glucose (TyG) …

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Magnesium depletion score is associated with arterial stiffness: data from the Brisighella Heart Study

Federica Fogacci, Marina Giovannini, Elisa Grandi, Sergio D’Addato et autres

BACKGROUND AND AIMS: The magnesium depletion score (MDS) estimates magnesium deficiency risk by integrating dietary intake and physiological losses. This study evaluated the association between MDS and arterial stiffness in a rural Mediterranean population. METHODS: We analyzed data from 2048 participants (49.2% …

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Sex differences in inflammatory biomarkers during long-term evolocumab therapy

Federica Fogacci, Serra İlayda Yerlitaş, Marina Giovannini, Egidio Imbalzano et autres

BACKGROUND Atherosclerotic cardiovascular disease remains a predominant cause of morbidity and mortality worldwide, driven by complex interactions between lipid metabolism and chronic inflammation. While evolocumab, a proprotein convertase subtilisin/kexin type 9 inhibitor, is established in lowering low-density lipoprotein cholesterol (LDL-C) and cardiovascular …

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Impact of treatment with evolocumab on biomarkers of chronic systemic and vascular inflammation

Federica Fogacci, Serra İlayda Yerlitaş, Marina Giovannini, Claudio Borghi et autres

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Healthy Eating beyond Whole Grains—Insight on Associations between Diet Quality and Arterial Stiffness in the Brisighella Heart Study Cohort

Marina Giovannini, Federica Fogacci, Sergio D’Addato, Elisa Grandi et autres

Although whole grains have well-recognized protective effects against the development of cardiometabolic diseases, whole grain foods are poorly consumed by the general population. The aim of our study was to establish, at a population level, the vascular impact of a low intake …

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Estimating prevalence and characteristics of patients potentially eligible for lipoprotein(a)-lowering therapies in a real-world setting

Arrigo F.G. Cicero, Federica Fogacci, Marina Giovannini, Elisa Grandi et autres

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Sex x time interactions in Lp(a) and LDL-C response to Evolocumab

Federica Fogacci, Serra İlayda Yerlitaş, Marina Giovannini, Gökmen Zararsız et autres

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SEX X TIME INTERACTIONS IN LP(A) AND LDL-C RESPONSE TO EVOLOCUMAB

Claudio Borghi, Marina Giovannini, Federica Fogacci, Serra İlayda Yerlitaş et autres

Effect of Supplementation of a Butyrate-Based Formula in Individuals with Liver Steatosis and Metabolic Syndrome: A Randomized Double-Blind Placebo-Controlled Clinical Trial

Federica Fogacci, Marina Giovannini, Valentina Di Micoli, Elisa Grandi et autres

Postbiotics could exert different metabolic activities in animal models of non-alcoholic fatty liver disease (NAFLD) and in humans affected by metabolic syndrome. This is a randomized, double-blind, placebo-controlled, parallel-group clinical trial that enrolled a sample of 50 Caucasian healthy individuals with NAFLD, …

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Effect of Coenzyme Q10 on Physical Performance in Older Adults with Statin-Associated Asthenia: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial

Federica Fogacci, Marina Giovannini, Giuliano Tocci, Egidio Imbalzano et autres

Background: Available evidence from randomized clinical trials is contrasting and definitely inconclusive in determining whether or not CoQ10 dietary supplementation is advisable in patients with statin intolerance or poor statin tolerability. Methods: This randomized, double-blind, placebo-controlled clinical study aimed at investigating the …

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A Randomized, Double-Blind, Placebo-Controlled Clinical Trial on the Effect of a Dietary Supplement Containing Dry Artichoke and Bergamot Extracts on Metabolic and Vascular Risk Factors in Individuals with Suboptimal Cholesterol Levels

Federica Fogacci, Marina Giovannini, Antonio Di Micoli, Giulia Fiorini et autres

The aim of this study was to assess whether dietary supplementation with a nutraceutical blend comprising extracts of bergamot and artichoke—both standardized in their characteristic polyphenolic fractions—could positively affect serum lipid concentration and insulin sensitivity, high-sensitivity C-reactive protein (hs-CRP), and indexes of …

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