Bayinchahan Gailike

Dominance of the E198A Mutation and Emergence of Co-Selection in Benzimidazole-Resistant Haemonchus contortus from Northwestern China

Waresi Tuersong, Lianxi Xin, Abudusaimaiti Tuoheti, Ailixire Maimaiti et autres

Background: Benzimidazole (BZ) resistance in the gastrointestinal nematode Haemonchus contortus is a major constraint to sheep production worldwide. However, data on the prevalence and molecular mechanisms of resistance in Yili Prefecture, Xinjiang—a key livestock region in Northwestern China—remain limited. This study aimed …

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Biological characterization of the ferritin 2 of Hyalomma anatolicum

Xueqing Zhao, Zeyun Cui, Na Zhou, Yuqian Deng et autres

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Integrated transcriptomic and proteomic analysis of the immune response in Hyalomma anatolicum to bacterial invasion

Jianlong Li, Tingxiang Luo, Zhen Ma, Depeng Yang et autres

Background: is a multi-host ectoparasite that carries and transmits a variety of zoonotic pathogens. Understanding the immune response of ticks to bacterial infections is of research significance for deciphering their immune defense mechanisms and harnessing tick - derived molecules. Methods: (PM group) …

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In Silico Analysis of Two Hard Tick P450s: Identification, Characterization, and Putative Metabolism of Cymbopogon citratus Essential Oil Constituents

Caishan Li, Wenyu Shi, Yuqian Deng, Xueqing Zhao et autres

The cytochrome p450 gene family is widely involved in various biological processes in arthropods. Tick p450s are often associated with chemical acaricides, but knowledge of their involvement in the metabolism of plant-derived essential oil components is limited. In this study, we identified …

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Molecular detection and population genetic diversity analysis of Theileria ovis in partial regions of Xinjiang, China

Meiling Wang, Xueqing Zhao, Wenyu Shi, Lu Gan et autres

Ovine theileriosis is a disease caused by the genus Theileria (e.g., T. ovis, T. lestoquardi), preventing the sheep farming industry from developing, particularly in regions reliant on sheep for milk, meat, and associated economic benefits. However, there is limited information available on …

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Evaluation of acaricidal effect of terpinolene and γ-terpinene on Hyalomma anatolicum and in silico screening of herbs

Caishan Li, Yuqian Deng, Ercha Hu, Bayinchahan Gailike

Importance: Terpenoids of a plant origin are a class of alternatives to chemical acaricides for tick control.Despite this, few studies have evaluated the efficacy of terpenoid-containing herbal extracts or individual terpenoids in Hyalomma anatolicum.Objective: This study evaluated the killing efficacy of terpinolene …

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Biological Characteristics of the Cytochrome P 450 Family and the Mechanism of Terpinolene Metabolism in Hyalomma asiaticum (Acari: Ixodidae)

Caishan Li, Xueqing Zhao, Wenlong Liu, Wenyu Shi et autres

The CYP450 enzyme is a superfamily enzyme ubiquitously found in nearly all organisms, playing a vital role in the metabolism of both endogenous and exogenous compounds, and in biosynthesis. Unfortunately, an understanding of its classification, functions, expression characteristics, and other biological traits …

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Distribution Prediction of Hyalomma asiaticum (Acari: Ixodidae) in a Localized Region in Northwestern China

Ercha Hu, Zhengxiang Hu, Xiaoyun Mi, Caishan Li et autres

Hyalomma tick species are considered the competent vector tick species that carry and transmit Crimean-Congo hemorrhagic fever virus (CCHFV) to humans and animals. Hyalomma asiaticum is one of the major tick species widespread in the Xinjiang Uygur Autonomous Region (XUAR) of China. …

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Evaluation of the genetic diversity and population structure of Gasterophilus pecorum in Xinjiang Province, China, using fluorescent microsatellites (SSR) markers

Shan-Hui Liu, Fang Cheng, XiaoZe Fan, Kai Li et autres

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