2026
article
OpenAlex
Zachary Warnken, Andrea Trementozzi, Mercy A. Okezue, Patricia P. Martins et autres
Abstract Intracellular infections impose fundamental physicochemical barriers that can disrupt antibiotic synergy observed under well-mixed in vitro conditions. Mycobacterium abscessus, a macrophage-resident pathogen, exemplifies this challenge, as co-administered drugs must traverse multiple membrane barriers and achieve coordinated intracellular exposure. The combination of …
us
(code pays fourni par la source)
Accès ouvert
2026
software
OpenAlex
Ashlee D. Brunaugh
A source-neutral Python toolkit for inverse gas chromatography analysis, quality control, plotting, explicit batch orchestration, and versioned neutral tabular inputs.
us
(code pays fourni par la source)
Accès ouvert
2026
software
OpenAlex
Ashlee D. Brunaugh
A provenance-aware pipeline for ingesting, quality-controlling, extracting features from, and comparing oscillatory rheology measurements exported by TA Instruments TRIOS.
us
(code pays fourni par la source)
Accès ouvert
2026
software
OpenAlex
Ashlee D. Brunaugh
A source-neutral Python toolkit for inverse gas chromatography analysis, quality control, plotting, explicit batch orchestration, and versioned neutral tabular inputs.
us
(code pays fourni par la source)
Accès ouvert
2026
software
OpenAlex
Ashlee D. Brunaugh
A provenance-aware pipeline for ingesting, quality-controlling, extracting features from, and comparing oscillatory rheology measurements exported by TA Instruments TRIOS.
us
(code pays fourni par la source)
Accès ouvert
2026
software
OpenAlex
Ashlee D. Brunaugh
A source-neutral Python toolkit for inverse gas chromatography analysis, quality control, plotting, and versioned neutral tabular inputs.
us
(code pays fourni par la source)
Accès ouvert
2026
software
OpenAlex
Ashlee D. Brunaugh
A source-neutral Python toolkit for inverse gas chromatography analysis, quality control, plotting, and versioned neutral tabular inputs.
us
(code pays fourni par la source)
Accès ouvert
2026
software
OpenAlex
Ashlee D. Brunaugh
A source-neutral Python toolkit for inverse gas chromatography analysis, quality control, plotting, and versioned neutral tabular inputs.
us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Bhanuz Dechayont, Ashlee D. Brunaugh
Abstract Curcumin exhibits antimicrobial activity against Gram-negative bacteria but is limited by rapid hydrolytic degradation at near-neutral pH. We hypothesized that chitosan, a cationic polymer that independently destabilizes the Gram-negative outer membrane, could simultaneously stabilize curcumin and potentiate its antibacterial activity. Curcumin …
us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Carolina H. Chung, David C. Chang, Nicole Rhoads, Prajna Lalitha et autres
Machine learning (ML) is necessary to efficiently identify potent drug combinations within a large candidate space to combat drug resistance. However, existing ML approaches cannot be applied to emerging and understudied pathogens with limited training data. Hence, we developed a computational framework …
us, in
(code pays fourni par la source)
2026
article
OpenAlex
Grace Xia, Nathan Bennette, Alan B. Watts, Ashlee D. Brunaugh
Optimizing inhalable protein powders requires simultaneously preserving protein structure and minimizing interparticle cohesion, yet the mechanistic links between excipient composition, drying physics, surface energetics, and aerosol performance remain poorly defined. Here, a constrained ternary mixture design of inulin, trehalose, and mannitol was …
us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Ziting Chen, Mariana Romero-Gonzalez, Andrea Maser, R. A. Leng et autres
Introduction . Burkholderia cenocepacia , a member of the Burkholderia cepacia complex (Bcc), causes severe, treatment-resistant lung infections in individuals with cystic fibrosis and chronic granulomatous disease. Hypothesis. We hypothesized that the C3HeB/FeJ mouse strain, characterized by impaired macrophage-mediated immunity, would be …
us
(code pays fourni par la source)