Accès ouvert
2023
article
OpenAlex
Henrik Ryberg, Anna‐Karin Norlén, Andreas Landin, Per Johansson et autres
Objective: Sex steroids exert important biological functions within the CNS, but the underlying mechanisms are poorly understood. The contribution of circulating sex steroids to the levels in CNS tissue and cerebrospinal fluid (CSF) has been sparsely investigated in human and with inconclusive …
se
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Accès ouvert
2023
article
OpenAlex
Claes Ohlsson, Maria Nethander, Anna‐Karin Norlén, Matti Poutanen et autres
CONTEXT: Epidemiological and preclinical data support cardiovascular, mainly protective, effects of sex steroids in men, but the mechanisms underlying the cardiovascular actions of sex steroids are poorly understood. Vascular calcification parallels the development of atherosclerosis, but is increasingly recognized as a diversified, …
se, fi, is
(code pays fourni par la source)
Accès ouvert
2022
supplementary-materials
OpenAlex
Hannah Colldén, Maria Nilsson, Anna‐Karin Norlén, Andreas Landin et autres
Supplemental information on method validation and supplemental figures
se
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Hannah Colldén, Maria Nilsson, Anna‐Karin Norlén, Andreas Landin et autres
A comprehensive atlas of sex steroid distribution in multiple tissues is currently lacking, and how circulating and tissue sex steroid levels correlate remains unknown. Here, we adapted and validated a gas chromatography tandem mass spectrometry method for simultaneous measurement of testosterone (T), …
se, fi
(code pays fourni par la source)
Accès ouvert
2021
supplementary-materials
OpenAlex
Hannah Colldén, Maria Nilsson, Anna‐Karin Norlén, Andreas Landin et autres
Supplementary figures for Comprehensive sex steroid profiling in multiple tissues reveals novel insights in sex steroid distribution in gonadal intact and orchiectomized male mice Deposited on 2021-12-23
se
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Accès ouvert
2021
article
OpenAlex
Claes Ohlsson, Marcus Langenskiöld, Kristian Smidfelt, Matti Poutanen et autres
CONTEXT: Male sex is a major risk factor for abdominal aortic aneurysms (AAA) but few studies have addressed associations between sex hormone levels and AAA. OBJECTIVE: We aimed to describe the associations between serum sex steroids and early, screening-detected AAA in men. …
se, fi
(code pays fourni par la source)
Accès ouvert
2021
supplementary-materials
OpenAlex
Claes Ohlsson, Marcus Langenskiöld, Kristian Smidfelt, Matti Poutanen et autres
Supplementary figures and tables to manuscript entitled “Low Progesterone and Low Estradiol Levels Associate with Abdominal Aortic Aneurysms in Men” Author Information: Claes Ohlsson, MD, PhD;1,2* Marcus Langenskiöld, MD, PhD;3* Kristian Smidfelt, MD, PhD;3 Matti Poutanen, PhD;1,4 Henrik Ryberg, PhD; 5 Anna-Karin …
se
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Accès ouvert
2015
article
OpenAlex
Maria Nilsson, Liesbeth Vandenput, Åsa Tivesten, Anna‐Karin Norlén et autres
Accurate measurement of sex steroid concentrations in rodent serum is essential to evaluate mouse and rat models for sex steroid-related disorders. The aim of the present study was to develop a sensitive and specific gas chromatography-tandem mass spectrometry (GC-MS/MS) method to assess …
us, se, fi
(code pays fourni par la source)
2013
article
OpenAlex
Kristina Dunér, Pernilla Bottner, Anna‐Karin Norlén
Analytical methods were developed for the determination of six metabolites of lesogaberan to be used in quantitative determinations of metabolites according to the guidelines of Metabolites in Safety Testing. The γ-amino butyric acid type B receptor agonist lesogaberan and its metabolites are …
se
(code pays fourni par la source)