Siobhán Casey

Intravenous Vitamin C for Patients Hospitalized With COVID-19

Simin Aysel Florescu, Dragos Stanciu, Mihaela Zaharia, Alma Kosa et autres

Importance: The efficacy of vitamin C for hospitalized patients with COVID-19 is uncertain. Objective: To determine whether vitamin C improves outcomes for patients with COVID-19. Design, Setting, and Participants: Two prospectively harmonized randomized clinical trials enrolled critically ill patients receiving organ support …

Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support–Free Days in Patients Hospitalized With COVID-19

Simin Aysel Florescu, Dragos Stanciu, Mihaela Zaharia, Alma Kosa et autres

IMPORTANCE: Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective: To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS: …

Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial

Simin Florescu, Delia Stanciu, Mihaela Zaharia, Alma Kosa et autres

Importance: The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. Objective: To determine the effect of multiple interventions for critically ill adults with COVID-19 on longer-term outcomes. Design, Setting, and Participants: Prespecified secondary analysis of …

The CHARTER-Ireland trial: can nebulised heparin reduce acute lung injury in patients with SARS-CoV-2 requiring advanced respiratory support in Ireland: a study protocol and statistical analysis plan for a randomised control trial

John Robert Sheehan, Pádraig Calpin, Maeve Kernan, Claire Kelly et autres

BACKGROUND: COVID-19 pneumonia is associated with the development of acute respiratory distress syndrome (ARDS) displaying some typical histological features. These include diffuse alveolar damage with extensive pulmonary coagulation activation. This results in fibrin deposition in the microvasculature, leading to the formation of …

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Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial

Yaseen M. Arabi, Anthony Gordon, Lennie Derde, Alistair Nichol et autres

sa, gb, nl, ie, au, ca, fr, nz, us, de, be (code pays fourni par la source)

Augmenting Critical Care Patient Monitoring Using Wearable Technology: Review of Usability and Human Factors

Evismar Andrade, Leo R. Quinlan, Richard Harte, Dara Byrne et autres

BACKGROUND: Continuous monitoring of the vital signs of critical care patients is an essential component of critical care medicine. For this task, clinicians use a patient monitor (PM), which conveys patient vital sign data through a screen and an auditory alarm system. …

ie, fr (code pays fourni par la source)

Novel Interface Designs for Patient Monitoring Applications in Critical Care Medicine: Human Factors Review

Evismar Andrade, Leo R. Quinlan, Richard Harte, Dara Byrne et autres

BACKGROUND: The patient monitor (PM) is one of the most commonly used medical devices in hospitals worldwide. PMs are used to monitor patients' vital signs in a wide variety of patient care settings, especially in critical care settings, such as intensive care …

ie, fr (code pays fourni par la source)

Augmenting Critical Care Patient Monitoring Using Wearable Technology: Review of Usability and Human Factors (Preprint)

Evismar Andrade, Leo R. Quinlan, Richard Harte, Dara Byrne et autres

BACKGROUND Continuous monitoring of the vital signs of critical care patients is an essential component of critical care medicine. For this task, clinicians use a patient monitor (PM), which conveys patient vital sign data through a screen and an auditory alarm system. …

ie, fr (code pays fourni par la source)

Novel Interface Designs for Patient Monitoring Applications in Critical Care Medicine: Human Factors Review (Preprint)

Evismar Andrade, Leo R. Quinlan, Richard Harte, Dara Byrne et autres

BACKGROUND The patient monitor (PM) is one of the most commonly used medical devices in hospitals worldwide. PMs are used to monitor patients’ vital signs in a wide variety of patient care settings, especially in critical care settings, such as intensive care …

ie, fr (code pays fourni par la source)

Critical care nurses’ knowledge of alarm fatigue and practices towards alarms: A multicentre study

Siobhán Casey, G Avalos, Maura Dowling

ie (code pays fourni par la source)