Valentina B. Gervazieva

Leptin and inflammation markers in children with allergic diseases and overweight

Svetlana A. Mazurina, Valentina B. Gervazieva

Мазурина С.А., Гервазиева В.Б

ALLERGIC DISEASES AND HELICOBACTER PYLORI INFECTION

Svetlana A. Mazurina, Valentina B. Gervazieva, V. V. Sveranovskaya

In children with allergic diseases and concomitant gastropathology by ELISA, the content of total IgE, IgG-, IgA- and sIgE- to H.pylori and cytokines IL-4 and IL-10 was determined in blood serum, in coprofiltrates - the content of CagA, IL-17, sIgA and sIgE …

ru (code pays fourni par la source)

Soy: allergenic properties of proteins and IgE cross-reactions

Valentina B. Gervazieva, Pavel V. Samoylikov, Е М Зайцев, Bykov As

Since the last century, European countries began to actively use soybean seeds as food additives or for food production with 100% milk and animal proteins replaced with soy. In Russia, soy is a relatively new agricultural crop, which recently began to be …

ru (code pays fourni par la source)

Different paterns of autoAbs in asthma-COPD overlap cogort

Anna Konishcheva, Valentina B. Gervazieva, Galina Leonidovna Osipova, Т. P. Оspelnikova et autres

The high heterogeneity of bronchial asthma (BA) and COPD endotypes and the lack of effective tools for early prognosis of its further progression and overlap (ACO) still represent the priority tasks in respiratory medicine. We have evaluated autoreactivity profiles in patients with …

ru (code pays fourni par la source)

Роль клещей Chortoglyphys Arcuatus (сем. Glycyphagidae ) в формировании бронхиальной астмы

Valentina B. Gervazieva, Т. И. Петрова, С. Л. Кожевникова, Tatiana M. Zheltikova et autres

Ten children aged 7 to 14 have been observed for 4 years in Cheboksary city: 4 children had bronchial asthma (BA) and 6 ones had bronchial asthma combined with allergic rhinitis (AR). The bronchial asthma occurred early in all the patients (before …

The autoreactivity phenomenon in the pathogenesis of asthma-COPD overlap (ACO)

Anna Konishcheva, Valentina B. Gervazieva, Galina Leonidovna Osipova, Т. P. Оspelnikova

The modern concept of development of bronchial asthma (BA) and chronic obstructive pulmonary disease (COPD) implies the leading role of immune reactions with the true inflammatory autoimmune pathogenetic components. Aim of the study was to evaluate the autoreactivity in patients with chronic …

ru (code pays fourni par la source)

Features of sensitization to molds and its role in development of respiratory allergic diseases

Valentina B. Gervazieva, Pavel V. Samoylikov, G. V. Vasilyeva

Over recent decades, a steady increase in the number of allergic diseases has been shown. Current evidence demonstrate a close association between their emergence and exposure to fungal allergens. In this regard, the aim of the present study was to identify frequency …

ru (code pays fourni par la source)

Disturbance in bacterial community composition affects inflammatory ambiance and structural changes in non-Th2 asthma

Anna Konishcheva, Valentina B. Gervazieva, Tatyana Ospelnikova

We aimed to establish a relationship between lower airways bacterial patterns, inflammation and remodeling in 59 stable non-Th2 asthma patients vs. 19 COPD using CT, mass-spectrometry bacteriome analysis and cytokine ELISA of induced sputum at baseline and after 1 year. Results: In …

ru (code pays fourni par la source)

Intestinal microbiota and allergic diseases

Svetlana A. Mazurina, Valentina B. Gervazieva, V. V. Sveranovskaya

The increase in allergic diseases over the past several decades is correlated with changes in the composition and diversity of the intestinal microbiota, which plays a significant role in the development of the immune system of the child. There are presented data …

ru (code pays fourni par la source)

ВИРУСЫ СЕМЕЙСТВА HERPESVIRIDAE И АУТОРЕАКТИВНОСТЬ У БОЛЬНЫХ БРОНХИАЛЬНОЙ АСТМОЙ

А. Ю. Конищева, Valentina B. Gervazieva

The immune response to the viruses from Herpesviridae family was evaluated by determining the levels of virus-specifi c IgG-AT and IgE-AT to HSV 1, EBV, CMV using an adapted ELISA method in patients with bronchial asthma (BA), along with IgE- and IgG4-autoAbs …

Biomarkers of inflammation and auto-Abs in asthma with obesity.

Anna Konishcheva, Valentina B. Gervazieva, Т. P. Оspelnikova

Obesity is considered as an independent risk factor for increased asthma prevalence, associated with severity,poorer control and non-eosinophilic inflammatory phenotype. The mechanisms of it’s impact, realized through the immunological proinflammatory activity of adipose tissue,still need to be elicited.We aimed to estimate the …

ru (code pays fourni par la source)

Autoantibodies IgE to thyroid antigens in patients with chronic urticaria

Svetlana A. Mazurina, P M Panteleymonova, Н А Сибгатуллина, Н. М. Рахматуллина et autres

.