Joseph G. Hollowell

2013 NS-AUA Abstracts

Abhijith Mally, Zeyad R. Schwen, Julie M. Riley, L Wang et autres

An Approach for Development of Age-, Gender-, and Ethnicity-Specific Thyrotropin Reference Limits

Laura Boucai, Joseph G. Hollowell, Martin I. Surks

BACKGROUND: The use of age- and ethnicity-specific thyrotropin (TSH) reference limits decreases misclassification of patients with thyroid dysfunction. Developing such limits requires TSH measurements in different subpopulations. METHODS: We determined, in the National Health and Nutrition Examination Survey III, the TSH median, …

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Extreme Longevity Is Associated with Increased Serum Thyrotropin

Gil Atzmon, Nir Barzilai, Joseph G. Hollowell, Martin I. Surks et autres

CONTEXT: The distribution of serum TSH shifts progressively to higher concentrations with age. OBJECTIVE: The aim of the study was to determine whether the population shift in TSH distribution to higher concentrations with aging extends to people of exceptional longevity, namely centenarians, …

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The prevalence of iodine deficiency in women of reproductive age in the United States of America

Joseph G. Hollowell, James E. Haddow

OBJECTIVE: To review the iodine status of women as assessed through National Health and Nutrition Examination Surveys from 1971 to 2002. DESIGN AND SETTING: National normative estimates of iodine status of the civilian, non-institutionalized population in the United States of America. SUBJECTS: …

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Age-Specific Distribution of Serum Thyrotropin and Antithyroid Antibodies in the U.S. Population: Implications for the Prevalence of Subclinical Hypothyroidism

Martin I. Surks, Joseph G. Hollowell

CONTEXT: Measurements from all age groups defined the upper limit of the TSH reference range in National Health and Nutrition Examination Survey III. The TSH median, 97.5 centile and prevalence of subclinical hypothyroidism (SCH), normal serum T(4) and TSH greater than 4.5 …

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National Health and Nutrition Examination Survey III Thyroid-Stimulating Hormone (TSH)-Thyroperoxidase Antibody Relationships Demonstrate That TSH Upper Reference Limits May Be Skewed by Occult Thyroid Dysfunction

Carole Ann Spencer, Joseph G. Hollowell, M. Kazarosyan, Lewis E. Braverman

CONTEXT: The setting of the TSH upper reference limit impacts the diagnosis of mild hypothyroidism and is currently controversial. OBJECTIVE: Our objective was to evaluate factors influencing the TSH reference range. DESIGN: Nonpregnant subjects aged 12 yr and older from National Health …

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Urine Iodine Measurements, Creatinine Adjustment, and Thyroid Deficiency in an Adult United States Population

James E. Haddow, Monica R. McClain, Glenn E. Palomaki, Joseph G. Hollowell

PURPOSE: The purpose of the study was to explore the relationships between urine iodine, creatinine, serum TSH, and total T(4) in a diverse population of U.S. adults with the aim of determining whether low urine iodine is associated with thyroid deficiency. METHODS: …

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Iodine Supplementation for Pregnancy and Lactation—United States and Canada: Recommendations of the American Thyroid Association

David Vaughn Becker, Lewis E. Braverman, François Delange, John T. Dunn et autres

The fetus is totally dependent in early pregnancy on maternal thyroxine for normal brain development. Adequate maternal dietary intake of iodine during pregnancy is essential for maternal thyroxine production and later for thyroid function in the fetus. If iodine insufficiency leads to …

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Urinary Iodine Concentration: United States National Health and Nutrition Examination Survey 2001–2002

Kathleen L. Caldwell, Robert L. Jones, Joseph G. Hollowell

Urine iodine has been measured in the U.S. population by the National Health and Nutrition Examination Survey (NHANES) since 1971. A downward trend was noted between NHANES I (320 +/- 6 microg/L in 1971-1974) and NHANES III (145 +/- 3 microg/L in …

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EQUIP: a worldwide program to ensure the quality of urinary iodine procedures

Kathleen L. Caldwell, Amir Makhmudov, Robert L. Jones, Joseph G. Hollowell

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Hematological and iron-related analytes--reference data for persons aged 1 year and over: United States, 1988-94.

Joseph G. Hollowell, Onno W. van Assendelft, Elaine W. Gunter, Brenda G. Lewis et autres

OBJECTIVES: This report presents national estimates of hematologic and iron-related analytes for persons 1 year of age and over, by age, sex, and race/ethnicity. METHODS: The analysis is based on data from the third National Health and Nutrition Examination Survey (NHANES III) …

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Are Detection and Treatment of Thyroid Insufficiency in Pregnancy Feasible?

Susan J. Mandel, Carole Ann Spencer, Joseph G. Hollowell

A workshop entitled, "The Impact of Maternal Thyroid Diseases on the Developing Fetus: Implications for Diagnosis, Treatment, and Screening," was held in Atlanta, Georgia, January 12-13, 2004. The workshop was sponsored jointly by The National Center on Birth Defects and Developmental Disabilities …

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