Lila Bhattarai

Initial and Subsequent Engagement of Recently Diagnosed Persons Living with HIV in Contact Tracing Interviews Conducted by Public Health Practitioners

John P Fulton, Thomas Bertrand, Aditya Khanna, Jon A. Steingrimsson et autres

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HIV and Other Sexually Transmitted Infections in Rhode Island: Trends, Disparities, and Health Equity.

Lila Bhattarai, Caroline Gummo, Thomas Bertrand, Emma Creegan et autres

Over the past 10 years, sexually transmitted infections (STIs) have seen a significant resurgence in the United States despite the availability of effective treatments and reliable prevention methods. Rhode Island has experienced a similar uptick in the incidence of syphilis, chlamydia and …

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Dynamics of clustering rates in the Rhode Island HIV-1 epidemic

Vlad Novitsky, Jon A. Steingrimsson, August Guang, Casey W. Dunn et autres

BACKGROUND: Characterizing HIV clustering rates and their trends over time can improve understanding a local epidemic and enhance its control. METHODS: Leveraging an academic-public health partnership in Rhode Island, we explored longitudinal dynamics of statewide clustering rates among key populations from 1991 …

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Prospective Evaluation of Routine Statewide Integration of Molecular Epidemiology and Contact Tracing to Disrupt Human Immunodeficiency Virus Transmission

Rami Kantor, Jon A. Steingrimsson, John P Fulton, Vladimir Novitsky et autres

Background: Human immunodeficiency virus (HIV) remains a global challenge and novel measures for transmission disruption are needed. Contact tracing is limited by reluctance or inability of newly diagnosed individuals to name at-risk contacts. Molecular cluster analysis is mostly used for outbreak investigations, …

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Acquired Human Immunodeficiency Virus Type 1 Drug Resistance in Rhode Island, USA, 2004–2021

Su Aung, Vlad Novitsky, Jon A. Steingrimsson, Fizza S. Gillani et autres

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) acquired drug resistance (ADR) compromises antiretroviral therapy (ART). METHODS: We aggregated all HIV-1 protease-reverse transcriptase-integrase sequences over 2004-2021 at the largest HIV center in Rhode Island and evaluated ADR extent, trends, and impact using Stanford …

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Integrating HIV Cluster Analysis in Everyday Public Health Practice: Lessons Learned From a Public Health–—Academic Partnership

John P Fulton, Vladimir Novitsky, Fizza S. Gillani, August Guang et autres

BACKGROUND: The use of molecular HIV cluster analysis to supplement public health contact tracing has shown promise in addressing HIV outbreaks. However, the potential of HIV cluster analysis as an adjunct to daily, person-by-person HIV prevention efforts remains unknown. We documented lessons …

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Epidemiological Patterns of HIV Diagnoses Among Women in Rhode Island: An Overview.

Lila Bhattarai, Meghan MacAskill, Erin C. Fuse Brown, Thomas Bertrand et autres

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2899. Integrating HIV Partner Services and Molecular Epidemiology Data to Enhance HIV Transmission Disruption in Rhode Island: Findings from a Public Health-Academic Partnership

Aditya Khanna, Vladimir Novitsky, August Guang, Mark Howison et autres

Abstract Background HIV remains a significant public health concern. Both contact tracing (identifying and notifying partners of people diagnosed with HIV) and molecular epidemiology (phylogenetic inference and cluster detection), are used to disrupt transmission. Integration of both modalities may be synergistic, though …

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An Automated Bioinformatics Pipeline Informing Near-Real-Time Public Health Responses to New HIV Diagnoses in a Statewide HIV Epidemic

Mark Howison, Fizza S. Gillani, Vlad Novitsky, Jon A. Steingrimsson et autres

Molecular HIV cluster data can guide public health responses towards ending the HIV epidemic. Currently, real-time data integration, analysis, and interpretation are challenging, leading to a delayed public health response. We present a comprehensive methodology for addressing these challenges through data integration, …

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Integrating HIV Cluster Analysis in Routine Public Health Prevention Efforts: Lessons Learned from a Statewide Public Health – Academic Partnership

John P Fulton, Vladimir Novitsky, Fizza S. Gillani, August Guang et autres

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Not all clusters are equal: dynamics of molecular HIV-1 clusters in a statewide Rhode Island epidemic

Vlad Novitsky, Jon A. Steingrimsson, Mark Howison, Casey W. Dunn et autres

OBJECTIVES: Molecular epidemiology is a powerful tool to characterize HIV epidemics and prioritize public health interventions. Typically, HIV clusters are assumed to have uniform patterns over time. We hypothesized that assessment of cluster evolution would reveal distinct cluster behavior, possibly improving molecular …

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Innovative Approaches to Promoting Health Equity through HIV Prevention in Rhode Island.

Lila Bhattarai, Meghan MacAskill, Thomas Bertrand, Katharine Howe et autres

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