Herman Sung Yu Liu

Chinese expert consensus on Bruton tyrosine kinase inhibitors in the treatment of B-cell malignancies

Yuqin Song, Shang‐Ju Wu, Zhixiang Shen, Donglu Zhao et autres

Targeted therapy with Bruton tyrosine kinase (BTK) inhibitors have revolutionized the treatment of patients with various B-cell malignancies. BTK inhibitors such as ibrutinib, zanubrutinib, orelabrutinib, and acalabrutinib have shown good clinical efficacy and better safety profiles than those of traditional chemotherapy and …

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Treatment outcome and prognostic factor analysis in transplant-eligible Chinese myeloma patients receiving bortezomib-based induction regimens including the staged approach, PAD or VTD

Chor Sang Chim, Albert Kwok Wai Lie, Eric Yuk Tat Chan, Herman Sung Yu Liu et autres

BACKGROUND: We have reported promising outcomes using a staged approach, in which bortezomib/thalidomide/dexamethasone was used only in 14 patients with suboptimal response to VAD (vincristine/adriamycin/dexamethasone) before autologous stem cell transplantation (ASCT). Here we compared the outcomes of the staged approach with frontline …

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Pattern of Thyroid Autoimmunity in Chinese Patients With Pernicious Anemia

Joyce C. W. Chan, Herman Sung Yu Liu, Bonnie Chi Shan Kho, Thomas Kwan Hang Lau et autres

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Pernicious Anemia in Chinese

Joyce C. W. Chan, Herman Sung Yu Liu, B C S Kho, Joycelyn Pui Yin Sim et autres

To study the clinical and hematologic features of pernicious anemia in Chinese, we describe 181 Chinese with megaloblastic anemia and low serum cobalamin, in association with either classic Schilling test results (82 patients) or the presence of serum antibody to intrinsic factor …

Monitoring of Chronic Myeloid Leukemia (CML) Imatinib Response by Fluorescence-In-Situ-Hybridization (FISH).

Sze Fai Yip, Thomas Shek Kong Wan, Albert Kwok Wai Lie, Herman Sung Yu Liu et autres

Abstract Glivec, a tyosine kinase inhibitor is the drug of choice for newly diagnosed chronic phase CML. Whilst Q-PCR is the most sensitive method to monitor response; cytogenetic analysis as well as FISH is routinely used in many laboratories. FISH has the …

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