Jonathan Boone

Updated duration of response for patients receiving dostarlimab plus carboplatin-paclitaxel treatment compared with patients receiving placebo plus carboplatin-paclitaxel in the ENGOT-EN6-NSGO/GOG-3031/RUBY trial

Mansoor Mirza, Lyndsay Willmott, Sakari Hietanen, Lucy Gilbert et autres

dk, us, fi, ca, hu, de, nl, it (code pays fourni par la source)

1118P Time to quality of life (QoL) deterioration in patients (pts) with mismatch repair proficient/microsatellite stable (MMRp/MSS) primary advanced or recurrent endometrial cancer (pA/rEC) and by population subgroups in the ENGOT-EN6-NSGO/GOG-3031/RUBY trial

Ingrid Boere, M. Edelson, Sakari Hietanen, L. Gilbert et autres

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Quality-adjusted time without symptoms of disease progression or toxicity of treatment in patients with primary advanced or recurrent endometrial cancer treated with dostarlimab plus carboplatin-paclitaxel versus carboplatin-paclitaxel

Dana M. Chase, Jørn Herrstedt, Eirwen M. Miller, Lucy Gilbert et autres

OBJECTIVE: In part 1 of the phase 3 RUBY trial (NCT03981796) in patients with primary advanced or recurrent endometrial cancer, dostarlimab plus carboplatin-paclitaxel significantly improved progression-free and overall survival vs placebo plus carboplatin-paclitaxel. Post hoc analyses examined the impact of adding dostarlimab …

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Predictors of Chronic Obstructive Pulmonary Disease (COPD) Readmissions Within 30 Days of Discharge: A Single Center Retrospective Analysis

L. Al Bizri, ERIC CARNIVALE, Jonathan Boone, O.M. Zeitouni et autres

Abstract Rationale: Acute exacerbations of COPD (AECOPD) requiring readmission within 30 days result in increased cost and mortality. We aimed at identifying the predictors related to those rehospitalizations in our academic center. Methods: A retrospective study was conducted comparing the demographic and …

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Elevated Carcinoembryonic Antigen and Eosinophilia: An Unclear Relationship in a Patient With Allergic Bronchopulmonary Aspergillosis

G E Hannigan, Jonathan Boone, Scott Parrish

Abstract Intro: Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity response to Aspergillus colonization in the airways characterized by recurrent asthma exacerbations including symptoms of productive cough, mucus plugging, and dyspnea. The biomarker carcinoembryonic antigen (CEA) is classically used to diagnose and monitor …

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A Cohort Study Exploring HPV Vaccination Beliefs Among Oral Health Providers: Broadening the Scope of Education and Administration

Leanne Brechtel, Larry C. Kilgore, Oluwafemifola Oyedeji, Alicia M. Mastronardi et autres

Background/Objectives: There is potential utility and increasing interest in engaging professionals in non-traditional vaccination settings to participate in efforts to reduce human papillomavirus (HPV)-related cancer. This study assessed the impact of a multi-disciplinary HPV educational intervention on oral health care professionals’ perceived …

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Start-Up Support Organizations: Challenges and Resilience During Crisis

Farzana Chowdhury, Jonathan Boone

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Physics-Based Watercraft Simulator in Virtual Reality

Kelly Ervin, Jonathan Boone, Karl Smink, Gaurav Savant et autres

In this paper, watercraft and ship simulation is summarized, and the way that it can be extended through realistic physics is explored. A hydrodynamic, data-driven, immersive watercraft simulation experience is also introduced, using the Unreal Engine to visualize a Landing Craft Utility …

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AI on digital twin of facility captured by reality scans

Indu Shukla, Rajeev Agrawal, Kelly Ervin, Jonathan Boone

The power of artificial intelligence (AI) coupled with optimization algorithms can be linked to data-rich digital twin models to perform predictive analysis to make better informed decisions about installation operations and quality of life for the warfighters. In the current research, we …

Oral Selinexor as Maintenance Therapy After First-Line Chemotherapy for Advanced or Recurrent Endometrial Cancer

Ignace Vergote, José Alejandro Pérez Fidalgo, Erika Hamilton, Giorgio Valabrega et autres

PURPOSE Selinexor inhibits exportin-1 (XPO1) resulting in nuclear accumulation of tumor suppressor proteins including p53 and has clinical activity in endometrial cancer (EC). The primary end point was to assess progression-free survival (PFS) with once-weekly oral selinexor in patients with advanced or …

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Object detection in synthetic aerial imagery using deep learning

Lalitha Dabbiru, C. Goodin, Daniel W. Carruth, Jonathan Boone

Object detection in aerial images is a challenging task as some objects are only a few pixels wide, some objects are occluded, and some are in shade. With the cost of drones decreasing, there is a surge in the amount of aerial …

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AI on digital twin of facility captured by reality scans

Indu Shukla, Rajeev Agrawal, Kelly Ervin, Jonathan Boone

The power of artificial intelligence (AI) coupled with optimization algorithms can be linked to data-rich digital twin models to perform predictive analysis to make better informed decisions about installation operations and quality of life for the warfighters. In the current research, we …

us (code pays fourni par la source)