Kritchai Vutipongsatorn

Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis

Joel M. Dulhunty, Stephen J. Brett, Jan J. De Waele, Dorrilyn Rajbhandari et autres

Importance: Whether β-lactam antibiotics administered by continuous compared with intermittent infusion reduces the risk of death in patients with sepsis is uncertain. Objective: To evaluate whether continuous vs intermittent infusion of a β-lactam antibiotic (piperacillin-tazobactam or meropenem) results in decreased all-cause mortality …

au, gb, be, nz, sg, fr (code pays fourni par la source)

Leveraging access to technology and enhanced surgical technique (LATEST) in laparoscopic bile duct exploration (LBDE)

Lalin Navaratne, Jasim Al‐Musawi, Kritchai Vutipongsatorn, Alberto Isla

Single-stage management of choledocholithiasis with concomitant gallstones consists of performing either laparoscopic bile duct exploration (LBDE) or intra-operative endoscopic retrograde cholangiopancreatography at the same time as laparoscopic cholecystectomy. Transductal LBDE is associated with significantly higher post-operative morbidity, longer operative times and longer …

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Perioperative group and save testing are not routinely indicated for emergency laparoscopic appendicectomy and laparoscopic hernia repairs: A North West London retrospective study

Jasim Al‐Musawi, Ieuan Reece, Jun Yu Chen, Clemency Britton et autres

INTRODUCTION: Two valid group and saves are commonly required for patients undergoing laparoscopic appendicectomy and laparoscopic hernia repairs preoperatively; however, perioperative blood transfusions are seldom required. This is financially burdensome and frequently leads to delays in theatre lists. We performed a retrospective …

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An evaluation of paired feedback from a year-long junior doctor-led teaching programme

Kritchai Vutipongsatorn, É. Nagy, Anup Jethwa, Amar Sharif et autres

Results24 doctors taught 124 students.Pre-to post-teaching programme scores improved significantly by between 12% and 21% for all domains (preparing teaching, presenting, providing feedback and knowledge -see Table 1.)The number of hours that doctors spent teaching significantly correlated with the improvement in their …

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Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study

Omar Kouli, Victoria Murray, Sanchita Bhatia, WA Cambridge et autres

BACKGROUND: Stratifying risk of postoperative pulmonary complications after major abdominal surgery allows clinicians to modify risk through targeted interventions and enhanced monitoring. In this study, we aimed to identify and validate prognostic models against a new consensus definition of postoperative pulmonary complications. …

Patient Stratification in Sepsis: Using Metabolomics to Detect Clinical Phenotypes, Sub-Phenotypes and Therapeutic Response

Humma Hussain, Kritchai Vutipongsatorn, Beatriz Jiménez, David Antcliffe

Infections are common and need minimal treatment; however, occasionally, due to inappropriate immune response, they can develop into a life-threatening condition known as sepsis. Sepsis is a global concern with high morbidity and mortality. There has been little advancement in the treatment …

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Inflammatory myopathy occurring shortly after severe acute respiratory syndrome coronavirus 2 vaccination: two case reports

Kritchai Vutipongsatorn, Anthony Isaacs, Ziad Farah

BACKGROUND: Vaccination remains the cornerstone approach to exiting the current global coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome coronavirus 2. The novel messenger ribonucleic acid vaccines offer a high level of protection and are widely used throughout the world. …

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Impact of postoperative acute kidney injury in patients undergoing major gastrointestinal surgery on 1-year survival and renal outcomes: a national multicentre cohort study

Kenneth A McLean, Sivesh K. Kamarajah, Emily Mills, James Glasbey et autres

BACKGROUND: The intermediate-term impact of acute kidney injury (AKI) in patients after major gastrointestinal and liver surgery has not been well characterized. This study aimed to evaluate the 1-year mortality rate and renal outcomes associated with postoperative AKI in a national prospective …

Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic

Kenneth A McLean, Sivesh K. Kamarajah, Dhruva Chaudhry, Rohan R Gujjuri et autres

BACKGROUND: This study aimed to determine the impact of pulmonary complications on death after surgery both before and during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. METHODS: This was a patient-level, comparative analysis of two, international prospective cohort studies: one …

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347 Read the First Page: An Audit on Medicine Reconciliation in General Surgery Inpatients at London District General Hospital

Kritchai Vutipongsatorn, Priya Patel, Anjan Prakash, Jasim Al Musawi

Abstract Aim Medication-related incidents occur more frequently when medicine reconciliation happens more than 24 hours after admission. The National Institute for Health and Care Excellence recommends a complete reconciliation within 24 hours of admission. General Surgery is a busy specialty with a …

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IMI Pathologic Myopia

Kyoko Ohno‐Matsui, Pei‐Chang Wu, Kenji Yamashiro, Kritchai Vutipongsatorn et autres

Pathologic myopia is a major cause of visual impairment worldwide. Pathologic myopia is distinctly different from high myopia. High myopia is a high degree of myopic refractive error, whereas pathologic myopia is defined by a presence of typical complications in the fundus …

jp, tw, gb, sg, hk, cn, fr, de (code pays fourni par la source)

The Effect of Non-Steroidal Anti-Inflammatory Drugs on Acute Pancreatitis: A Retrospective Study at a London District General Hospital

Kritchai Vutipongsatorn, Noman Zafar, Zaed Hamady, Jasim Al‐Musawi

Context Acute pancreatitis (AP) is a common emergency condition. Despite a complication rate of up to 20%, current management only includes supportive treatment and surgery in specific circumstances. Non-steroidal anti-inflammatory drugs (NSAIDs) are shown to reduce post-endoscopic retrograde cholangiopancreatography pancreatitis. Objective To …