Halen Baker Erdman

Embracing Diversity: Sedative effects vary across drug chemistry and frequency domains

Jing Guang, Halen Baker Erdman, Orilia Ben-Yishay Nizri, Shimon Firman et autres

Moderate sedation can balance patients' comfort and preserve brain activities during deep brain stimulation neurosurgical procedures; however, the sub-cortical effects of different sedatives are rarely explored. We simultaneously recorded EEG, local field potential (LFP), and spikes (multi- and single-unit) from the dorsolateral …

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Innovative care protocol successfully rehabilitates non-human primates after MPTP-induced parkinsonism: Preliminary evidence from a restricted cohort of African Green Monkeys ( Chlorocebus sabaeus )

Tamar Ravins Yaish, Noa Eshkol Noy, Rony Kalman, Jing Guang et autres

The MPTP-animal model of Parkinson's disease has significantly advanced our understanding of Parkinson's disease and the dopaminergic system, helping to establish disease mechanisms and develop therapeutic targets. The non-human primate (NHP) MPTP model is particularly valuable for replicating core Parkinson's disease motor …

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Is the Subthalamic Nucleus Sleeping Under Nitrous Oxide–Ketamine General Anesthesia?

Halen Baker Erdman, Hagai Bergman, Karin Abu Haya, Stefanie Glowinsky et autres

Nitrous oxide is a common gaseous anesthetic used in a wide range of medical procedures due to its desirable combination of anesthetic and analgesic properties. Deep brain stimulation surgery, a well-established treatment for movement disorders like Parkinson's disease, often requires precise microelectrode …

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Author response for "Is the Subthalamic Nucleus Sleeping Under Nitrous Oxide-Ketamine General Anesthesia?"

Halen Baker Erdman, Hagai Bergman, Karin Abu Haya, Stefanie Glowinsky et autres

Pathological beta power increase in the subthalamic nucleus is absent in essential tremor

Halen Baker Erdman, Hagai Bergman, Juan F. León, Sami Heymann et autres

Abstract Parkinson’s disease and essential tremor are common movement disorders characterized by distinct motor symptoms. Deep brain stimulation targeting the subthalamic nucleus has shown efficacy in managing Parkinson’s disease symptoms, whereas the posterior subthalamic area is an emerging target for essential tremor. …

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Ketamine for Conscious Sedation in Deep Brain Stimulation Surgery

Idit Tamir, Evgeniya Kornilov, Halen Baker Erdman, Hagai Bergman

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Atrophy-related corticospinal changes in advanced Parkinson's disease are associated with the genetic etiology of the disease

Roy Dayan, Atira Bick, Caroline Weill, Max Bauer et autres

Background Compensatory mechanisms in Parkinson's disease (PD) are thought to explain the temporal delay between the beginning of the neurodegenerative process and the appearance of clinical signs. The enhanced structural integrity of the corticospinal tract was previously suggested as one of these …

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Interleaved Propofol‐Ketamine Maintains DBS Physiology and Hemodynamic Stability: A Double‐Blind Randomized Controlled Trial

Evgeniya Kornilov, Halen Baker Erdman, Eilat Kahana, Shlomo Fireman et autres

BACKGROUND: The gold standard anesthesia for deep brain stimulation (DBS) surgery is the "awake" approach, using local anesthesia alone. Although it offers high-quality microelectrode recordings and therapeutic-window assessment, it potentially causes patients extreme stress and might result in suboptimal surgical outcomes. General …

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Novel RAB39B Mutation Causes Parkinsonism in Males with Developmental Disorder

Roy Dayan, S. Shkedi Rafid, Halen Baker Erdman, Caroline Weill et autres

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Deep brain stimulation surgery under ketamine induced conscious sedation: a double blind randomized controlled trial

Evgeniya Kornilov, Halen Baker Erdman, Eilat Kahana, Shlomo Fireman et autres

Abstract Background The gold standard anesthesia for deep brain stimulation (DBS) surgery is the “awake” approach, using local anesthesia alone. While it offers high-quality microelectrode recordings and clinical assessment of the stimulation therapeutic window, it potentially causes patients extreme stress and might …

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Reply to: “Subthalamic Physiology in Genetic Subtypes of Parkinson's Disease”

Caroline Weill, Akiva Gallant, Halen Baker Erdman, Muneer Abu Snineh et autres

N/A.

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Utility of MRI in surgical planning for parasagittal meningiomas

John S. Winestone, Halen Baker Erdman, Musa Khweis, Eliel Ben-David et autres

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