Micah Harris

Radiation dose modulates plate complications in patients undergoing maxillo-mandibular reconstruction

Micah Harris, Jeff Shogan, Joshua D. Smith, Kevin J. Contrera et autres

BACKGROUND: Despite carrying significant complication risk, titanium plates remain the standard-of-care in the reconstruction of segmental mandibulectomy defects. Radiation therapy (RT) is known to impair wound healing and cause dose perturbation at the metal-tissue interface. In this study, we sought to investigate …

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Diagnostic Tonsillectomy and Surgical Margins After Completion Lateral Oropharyngectomy

Micah Harris, Akshaya Raman, Shivam Patel, Joshua D. Smith et autres

This cohort study examines the role of prior tonsillectomy in higher positive margins or worse survival among patients with human papillomavirus–associated tonsillar squamous cell carcinoma.

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Corrigendum: Outcomes of Extended Middle Fossa Approach for Petroclival Tumors in the Elderly

Vivian F. Kaul, Micah Harris, Masanari Kato, Guilherme Finger et autres

Correction to: Outcomes of Extended Middle Fossa Approach for Petroclival Tumors in the Elderly J Neurol Surg B Skull Base 2024; 85(S 02): e110-e116 DOI: 10.1055/a-2219-2551 It has been brought to the publisher's attention that in the article published in the Journal …

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Integrating artificial intelligence-driven digital pathology and genomics to establish patient-derived organoids as new approach methodologies for drug response in head and neck cancer

Rose Doerfler, Jie Chen, Carl Kim, Joshua D. Smith et autres

• PDO system models HPV-negative HNSCC across clinical and demographic backgrounds. • TransferNet-PDO, a novel AI tool, accurately classifies tumor vs. normal PDOs. • PDOs preserve clonal architecture and low-prevalence subclones over time. • PDOs reveal patient-specific drug responses to standard treatment …

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The Price of Paralysis: Analyzing the Direct Cost of Facial Rehabilitation after Vestibular Schwannoma Resection

Robert J. Macielak, Micah Harris, Vivian F. Kaul, Leslie Kim et autres

Objective: To estimate the direct costs associated with facial nerve rehabilitation for patients with facial paralysis after vestibular schwannoma (VS) resection. Study Design: Retrospective cohort study. Setting: Academic tertiary referral center. Participants: Patients treated sequentially between September 2016 and May 2021 who …

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Integrating Artificial Intelligence-Driven Digital Pathology and Genomics to Establish Patient-Derived Organoids as a Novel Alternative Model for Drug Response in Head and Neck Cancer

Rose Doerfler, Jie Chen, Carl Kim, Joshua D. Smith et autres

Abstract Patient-derived organoids (PDOs) are emerging as advanced 3D ex vivo novel alternative method (NAM) preclinical models, offering significant advantages over traditional cell lines and monolayer cultures for therapeutic development. In this study, we established PDOs from surgically resected fresh tissues of …

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Incidence, Morbidity, and Mortality of Pulmonary Complications in Free Flap Reconstruction: Limitations of Predictive Models

Nana‐Hawwa Abdul‐Rahman, Micah Harris, Matthew T. Bottegal, Shaum Sridharan et autres

OBJECTIVE: Herein, we evaluate the incidence, risk factors, and prognostic implications of postoperative pulmonary complications (PPCs) in head and neck microvascular free flap (MVFF) reconstruction. Current prediction models were assessed, and a head and neck MVFF-specific model is proposed. STUDY DESIGN: Retrospective …

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Emerging Proximal Liquid Biopsy Approaches for Detecting Residual Disease and Predicting Recurrence in Head and Neck Cancer: A Review and Proposal of Novel Liquid Staging

Vanessa Helou, Joshua D. Smith, Micah Harris, Noah Earland et autres

BACKGROUND: Head and neck squamous cell carcinoma remains challenging due to high recurrence rates and poor survival outcomes. Developing precise technologies for disease burden assessment, treatment response, and minimal residual disease (MRD) surveillance is crucial for improving prognosis. METHODS: This review explores …

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Bivalirudin for unsalvageable venous congestion or obstruction in head and neck free flap reconstruction

Micah Harris, Sophia Dang, Joshua D. Smith, Steven B. Chinn et autres

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A qualitative analysis of pediatric otolaryngology fellowship websites

Micah Harris, Nathan Lu, Anthony Tang, Natasha Mayer et autres

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A nomogram to predict long-term facial nerve function after vestibular schwannoma resection: a contemporary multi-institutional study

Micah Harris, Robert J. Macielak, Vivian F. Kaul, Lisa Zhang et autres

OBJECTIVE: The objective of this study was to develop a nomogram to predict long-term facial nerve (FN) function after vestibular schwannoma (VS) resection. METHODS: A retrospective cohort study of two tertiary academic skull base referral centers was performed. Consecutive adults > 18 …

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The role of induction chemotherapy for orbital invasion in sinonasal malignancies: A systematic review

Anthony Tang, Michael J. Calcaterra, Micah Harris, Paul A. Gardner et autres

BACKGROUND: Sinonasal malignancies (SNMs) frequently present with orbital invasion. Orbital exenteration (OE) can lead to significant morbidity. Induction chemotherapy (IC) is a promising treatment alternative that may allow for orbit preserving (OP) treatments without compromising patient survival. This systematic review was conducted …

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