2026
article
OpenAlex
Hazim Khatib, Amit Parizat, Jabour Halloun, Roni Shouval et autres
ABSTRACT CAR‐T cell therapy is efficient in relapsed/refractory B‐cell lymphoma; yet, cytokine release syndrome (CRS) and immune effector cell‐associated neurotoxicity syndrome (ICANS) remain major and potentially life‐threatening complications, which makes their prediction and prevention crucial. This international, retrospective study analyzed the predictive …
il, us
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2024
article
OpenAlex
Mayasa Abu Ata, Israel Henig, Dana Yehudai‐Ofir, Inna Tzoran et autres
INTRODUCTION: Chimeric antigen receptor T (CAR-T) cell therapy, emerging as an efficient treatment option for patients with secondary central nervous system (CNS) lymphoma, is frequently complicated with immune effector cell-associated neurotoxicity syndrome (ICANS). CASE PRESENTATION: We report a case of a 64-year-old …
il
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Accès ouvert
2024
article
OpenAlex
Tsofia Inbar, Eldad J. Dann, Omer Kerner, Anat Stern
BACKGROUND: Patients with severe B-cell depletion related to hematological malignancies or B-cell targeted therapy suffer from impaired antibody responses to SARS-CoV-2 and are at risk for prolonged COVID-19. In this population, COVID-19 convalescent plasma (CCP) may provide passive immunity, enhance immune response, …
il
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2023
conference-abstract
OpenAlex
Tamar Tadmor, Ohad Benjamini, Neta Goldschmidt, Natalia Kreiniz et autres
Background: Richter's syndrome (RS) is an aggressive histologic transformation of chronic lymphocytic leukemia (CLL), most commonly to diffuse large B-cell lymphoma (DLBCL). RS is characterized by a rapid clinical course, low responses to therapy, and poor long-term survival. Chemoimmunothreapy for RS achieves …
il
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Accès ouvert
2023
article
OpenAlex
Eldad J. Dann, Jamela Eisa, Tsofia Inbar, Shada Sarji et autres
Topic: 17. Hodgkin lymphoma - Clinical Background: The incidence of Hodgkin lymphoma (HL) among the Eastern Mediterranean population is very high. The highest rates are reported in Lebanese males (4.2x105) followed by Israeli males (3.7x105), with values being similar in Jews and …
il
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2022
article
OpenAlex
Shimrit Harlev, Nashwa Fadaos, Tehila Azoulay, Ronit Leiba et autres
The results of the PRIMA trial published a decade ago, substantiated the benefit of maintenance therapy with anti-CD20 monoclonal antibodies (MoAb), following chemo-immunotherapeutic induction, for prolongation of the progression-free survival (PFS) of patients with high-tumor- burden follicular lymphoma (FL). Rituximab-associated delayed neutropenia, …
il
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Accès ouvert
2022
article
OpenAlex
Eldad J. Dann, Tsofia Inbar, Tania Mashiach, Jamela Eisa et autres
Background: In patients (pts) with hematological malignancies, COVID-19 is considered to be associated with a high risk of severe morbidity and mortality. While anti-COVID-19 vaccination of such pts has become the standard of care, pts undergoing lymphodepleting therapy fail to generate protective …
il
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Accès ouvert
2022
article
OpenAlex
Ronit Gurion, Uri Rozovski, Gilad Itchaki, A. Gafter-Gvili et autres
Background: In most individuals, protective humoral and cellular immunity develops after two doses of the BNT162b2 Pfizer vaccine. In patients with lymphoma, humoral response is weaker and almost universally abrogated in patients who received anti-CD20 monoclonal antibodies. Whether cellular immune response is …
il
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Accès ouvert
2021
conference-abstract
OpenAlex
Eldad J. Dann, Tsofia Inbar, Tania Mashiach, Jamela Eisa et autres
Abstract Introduction: In patients with hematological malignancies, COVID-19 is considered to be associated with a high risk of severe morbidity and mortality. While anti-COVID-19 vaccination of such patients has become the standard of care, many of them fail to generate protective serological …
il
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Accès ouvert
2021
article
OpenAlex
Ronit Gurion, Uri Rozovski, Gilad Itchaki, Anat Gafter‐Gvili et autres
Patients with lymphoma, especially those treated with anti-CD20 monoclonal antibodies, suffer high COVID-19-associated morbidity and mortality. The goal of this study was to assess the ability of lymphoma patients to generate a sufficient humoral response after two injections of BNT162b2 Pfizer vaccine …
il
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Accès ouvert
2021
article
OpenAlex
Liza Barki‐Harrington, Orna Baron‐Epel, Adir Shaulov, Luiza Akria et autres
BACKGROUND: One of the main obstacles of providing home-based palliative care to transfusion-dependent hematology patients is the lack of home transfusions services. While healthcare professionals are concerned with safety and cost of home transfusions, the attitude of the patients toward home transfusions …
il
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2019
article
OpenAlex
Tsofia Inbar, Shehrban Sobeh Khalil, Ron Ram, Chezi Ganzel et autres
The natural history of chronic hepatitis B virus (HBV) infection is highly dependent on the immune response of the infected individual. Patients on immunosuppressive therapy, with prior exposure to...
il
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