Christopher G. Willett

Consumer protection and the digital economy

Christopher G. Willett, Elisabetta Bergamini

The chapters in this collection seek to offer fresh analysis of a range of challenges and opportunities that digitalisation of consumer markets brings for law and regulation. In this introductory chapter, we summarise some of these risks, opportunities, and legal responses that …

Consumer Protection and the Digital Economy

Christopher G. Willett, Elisabetta Bergamini

This chapter examines the impact of artificial intelligence (AI) on consumer rights within the EU Digital Single Market, against the backdrop of the recently adopted AI Act and pre-existing legal instruments. While AI technologies can enhance consumer protection – by fostering informed …

Pembrolizumab, Radiotherapy, and Chemotherapy in Neoadjuvant Treatment of Malignant Esophago‐gastric Diseases (PROCEED): A single‐arm phase 2 trial

Pooja Karukonda, Brian G. Czito, Eileen A. Duffy, Hope Elizabeth Uronis et autres

INTRODUCTION: Esophagogastric cancers are common and carry a poor prognosis. A standard option for locally advanced disease has been neoadjuvant chemoradiation (CRT) followed by surgical resection. The primary goal of this study was to investigate whether the addition of pembrolizumab to neoadjuvant …

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Radiation Therapy for Gastric Cancer: An ASTRO Clinical Practice Guideline

Christopher James Anker, Junaid Arshad, Francesco Cellini, Ahmed N. Dehal et autres

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Gastric Cancer, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology

Jaffer A. Ajani, Thomas Anthony D’Amico, David J. Bentrem, Carlos Uriel Corvera et autres

Gastric cancer is the fifth leading cause of cancer-related deaths worldwide. Over 95% of gastric cancers are adenocarcinomas, which are typically classified based on anatomic location and histologic type. Gastric cancer generally carries a poor prognosis because it is often diagnosed at …

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Characterisation and Sensitivity Analysis of the Force-Displacement Behaviour of Bistable Unsymmetric Composite Plates

Christopher G. Willett, Robert Dorey, Andrew Viquerat

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NCCN Guidelines® Insights: Rectal Cancer, Version 3.2024

Al B. Benson, Alan Paul Venook, Mohamed A. Adam, George J. Chang et autres

The determination of an optimal treatment plan for an individual patient with rectal cancer is a complex process. In addition to decisions relating to the intent of rectal cancer surgery (ie, curative or palliative), consideration must also be given to the likely …

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Colon Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology

Al B. Benson, Alan Paul Venook, Mohamed A. Adam, George J. Chang et autres

Colorectal cancer (CRC) is the fourth most frequently diagnosed cancer and the second leading cause of cancer death in the United States. Management of disseminated metastatic CRC involves various active drugs, either in combination or as single agents. The choice of therapy …

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Updates in the Management of Locally Advanced Rectal Cancer

Christopher G. Willett

A plethora of advancements in the management of locally advanced rectal cancer continue to be developed. Treatment strategies have primarily focused on modifying the current standard paradigm of rectal cancer management—including the complete omission of surgery or radiotherapy, or instead using immunotherapy …

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Neoadjuvant Short- Vs. Long-Course Radiation for Locally Advanced Rectal Cancer: How to Choose

Christopher G. Willett, Scarlett Acklin-Wehnert

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Management of Metastic Liver Cancer

Camille L. Stewart, Felix Ho, Yuman Fong, S. Lindsey Davis et autres

The liver is the most common site for blood-borne metastasis from colorectal cancers, and is the dominant metastatic disease site just prior to death (Stewart et al. 2018). Until the early 1980s, it was generally accepted that hepatic metastases from colorectal cancer …

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Pembrolizumab, radiotherapy, and chemotherapy in neoadjuvant treatment of malignant esophago-gastric diseases (PROCEED): Assessment of survival and patterns of recurrence in a prospective, phase II single-arm trial.

Pooja Karukonda, Dominic LaBella, Brian G. Czito, Eileen A. Duffy et autres

375 Background: Locally advanced esophagogastric adenocarcinoma (EGA) is commonly treated with neoadjuvant chemoradiation (CRT) prior to surgical resection. Adjuvant immunotherapy has been shown to improve outcomes for these patients. The primary objective of this trial was to investigate whether neoadjuvant pembrolizumab (P) …

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