Han Sun

Dual-function niobium-doped carbon dots for ferroptosis-driven anti-inflammatory therapy in pseudomonas aeruginosa pneumonia via GPX4 axis

Na Zhang, Shiqing Yang, Fructueux Modeste Amona, Yongbo Yu et autres

Escalation of antimicrobial resistance (AMR) and the complex pathophysiology of severe hospital-acquired Pseudomonas aeruginosa (PA) pneumonia, driven by a vicious cycle of oxidation-inflammation and ferroptosis, require innovative therapeutic strategies beyond traditional antibiotics. Host-directed therapies that modulate immune responses and reduce tissue damage …

cn (code pays fourni par la source)

A dual-hijack strategy coordinating BBB transcytosis and intracellular ferritinophagy for glioblastoma gene therapy

Tianran Chai, Z Q Chen, Tengfei Guo, M Liu et autres

Systemic gene therapy for glioblastoma is limited by poor brain-tumor delivery and resistance to apoptosis-based treatments. Here, we developed an ApoE-functionalized lipid nanoparticle (ApoE-LNP) for plasmid delivery of Ncoa4 , aiming to couple BBB transcytosis with ferritin/iron turnover–driven ferroptosis. ApoE-LNPs showed uniform …

cn, us, kr (code pays fourni par la source)

Synergistic bimetallic catalysis and heterointerface engineering in MgFe LDH-biochar enhancing non-radical-dominated antibiotic degradation

Jie Ren, Mengfan Li, Han Sun, Ruosong Jing et autres

cn (code pays fourni par la source)

Rational design of iodinated silicon-fluorescein photosensitizers for optimal photodynamic efficacy

Junshuai Ding, Yutong Shao, Han Sun, Ran An et autres

Herein, we investigate how iodine incorporation modulates the ROS kinetics of silicon-fluorescein derivatives, activating both Type I and II pathways that transcend empirical heavy-atom counting for optimal photodynamic therapy.

cn (code pays fourni par la source)

High-efficiency photocatalytic degradation of multiple quinolone antibiotics using a hybrid heterojunction with synergistic doping of boron and bismuth

Han Sun, Yonghao Dong, Lei Wang, Xudong Wang et autres

cn (code pays fourni par la source)

Achieving carrier migration pathway transformation to enhance photocatalytic moxifloxacin degradation activity by regulating the Fermi Level of g-C3N4/ ZnIn2S4 through sulfur vacancies

Han Sun, Yonghao Dong, Lei Wang, Xudong Wang et autres

cn (code pays fourni par la source)

Unseen Visual Anomaly Generation

Han Sun, Yunkang Cao, Hao Dong, Olga Fink

Visual anomaly detection (AD) presents significant challenges due to the scarcity of anomalous data samples. While numerous works have been proposed to synthesize anomalous samples, these synthetic anomalies often lack authenticity or require extensive training data, limiting their applicability in real-world scenarios. …

ch (code pays fourni par la source)

Transcriptome Analysis Reveals Possible Antitumor Mechanism of Intracellular Polysaccharide From Phaeodactylum tricornutum on Cervical Cancer HeLa Cells

Han Sun, Zhongwen Liang, Ying Qin Zang, Song Liu et autres

Seaweed polysaccharide, a naturally occurring, non-toxic antitumor substance, has emerged as a significant focus of research. In this study, intracellular polysaccharides from Phaeodactylum tricornutum (PRP) were isolated and purified to investigate their antitumor effects and underlying mechanisms. The inhibitory effects of various …

cn (code pays fourni par la source)

Defect-regulated and amino-functionalized UiO-67 for efficient removal of tetracycline hydrochloride from aqueous solutions

Yonghao Dong, Xudong Wang, Han Sun, Xiaochen Zhao et autres

cn (code pays fourni par la source)

Constructing a stable photocatalytic functional layer through cross-linking of chitosan and l-mannose for efficient removal of doxycycline hydrochloride in single-pass flow mode

Yonghao Dong, Xudong Wang, Han Sun, Xiaochen Zhao et autres

cn (code pays fourni par la source)

In vivo fluorescence flow cytometry reveals that the nanoparticle tumor vaccine OVA@HA-PEI effectively clears circulating tumor cells

Wei Jin, Yuting Fu, Sisi Ge, Han Sun et autres

Tumor vaccine therapy offers significant advantages over conventional treatments, including reduced toxic side effects. However, it currently functions primarily as an adjuvant treatment modality in clinical oncology due to limitations in tumor antigen selection and delivery methods. Tumor vaccines often fail to …

cn (code pays fourni par la source)

Automated Apoptosis Identification in Fluorescence Imaging of Nucleus Based on Histogram of Oriented Gradients of High-Frequency Wavelet Coefficients

Shutong Liu, Limei Su, Han Sun, Tongsheng Chen et autres

cn (code pays fourni par la source)