Xianghao Zeng

Design, synthesis and evaluation of novel L-tryptophan derivatives as multifunctional agents with cholinesterase inhibition, anti-β-amyloid aggregation, anti-inflammatory, antioxidant and neuroprotection properties against Alzheimer's disease

Haiyang Yu, Yinfang Chen, Huizhen Li, Zhiqiang Li et autres

In our recent investigation, we conducted a systematic search for novel L -Tryptophan derivatives exhibiting marked inhibitory effects against human serum butyrylcholinesterase ( h BuChE), an enzyme intricately implicated in the pathological cascade of Alzheimer's Disease (AD). Two lead compounds among these …

cn (code pays fourni par la source)

Design, synthesis, and activity evaluation of novel multitargeted l ‐tryptophan derivatives with powerful antioxidant activity against Alzheimer's disease

Xianghao Zeng, Shaobing Cheng, Huilan Li, Haiyang Yu et autres

Abstract Alzheimer's disease (AD) is a multifactorial neurological disease, and the multitarget directed ligand (MTDL) strategy may be an effective approach to delay its progression. Based on this strategy, 27 derivatives of l‐tryptophan, 3a‐1–3d‐1, were designed, synthesized, and evaluated for their biological …

cn (code pays fourni par la source)

Integration of Antioxidant Activity, Affinity Ultrafiltration, and Molecular Docking Simulations to Decipher the Tyrosinase Inhibitor of Embelia laeta

Wanting Li, Zhiqiang Li, Huimin Yu, Xianghao Zeng et autres

cn (code pays fourni par la source)

Ethanol addition during aqueous phase recirculation for further improving bio-oil yield and quality

Xinfei Chen, Xiaoqian Ma, Xianghao Zeng, Chupeng Zheng et autres

cn (code pays fourni par la source)

Numerical simulation of co-incineration of sewage sludge and municipal solid waste in municipal solid waste incinerator

Haichuan Wang, Yanfen Liao, Xiaoqian Ma, Xianghao Zeng

Incineration is widely used as an important method of sludge and garbage utilization and harmless treatment. The simulations of co-incineration of sludge and municipal solid waste are conducted by computational fluid dynamics method(CFD) in a MSW incinerator. The study focuses on the …

cn (code pays fourni par la source)