P.M. Casole

Study of Cell Kinetics in the Normal Colorectal Mucosa of Subjects at Risk of Developing Colorectal Carcinoma

Lucia De Franceschi, Laura Monteiro de Castro Conti, Laura Moro, Vittorio Francavilla et autres

This report examines the 3H-thymidine-labeling index (LI), the flow cytometric S-phase cell fraction, and DNA ploidy in the normal colorectal mucosa of three groups of subjects: normal subjects (group A), patients with adenomas (group B) and patients with cancer (group C). The …

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Evaluation of some biological parameters for the early diagnosis of cancer of the large intestine

V. Casale, Pierluigi Fracasso, P.M. Casole, A M Cianciulli et autres

Detection of C-myb genetic alterations and mutant p53 serum protein in patients with benign and malignant colon lesions.

Claudia Greco, Gandolfo Gm, Fabrizio Mattei, Angela Gradilone et autres

C-myb structural alterations were analysed by Southern blot hybridization in 55 adenomatous polyps and 21 adenocarcinomas of the colon. Gene amplification was observed in 8 cases (14.5%) and c-myb rearrangements in 3 cases (5.4%) of the preneoplastic lesions analysed. A higher percentage …

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[Colonic varices secondary to recurrent acute pancreatitis].

Pierluigi Fracasso, Renato Caviglia, Alberto Grassi, R. Lapenta et autres

Colonic varices are a rare finding, with variable clinical features. The authors describe the first case of colonic varices secondary to acute recurrent pancreatitis, and associated with colon cancer. There are about 70 reports of colonic varices; none of them is related …

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