Supplementary File 2 from Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma
Joshua P. Plotnik, Adam E. Richardson, Haopeng Yang, Estela Rojas et autres
Excel Workbook RNASeq
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Estela Rojas
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Supplementary Figure 1 from Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma
Joshua P. Plotnik, Adam E. Richardson, Haopeng Yang, Estela Rojas et autres
Pan-lineage PRISM analysis of ABBV-MALT1 sensitivity.
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Supplementary Figure 7 from Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma
Joshua P. Plotnik, Adam E. Richardson, Haopeng Yang, Estela Rojas et autres
MALT1 and BCL2 inhibition do not antagonize each other in monotherapy sensitive patient derived xenografts
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Blunted CD40-responsive enhancer activation in CREBBP-mutant lymphomas can be restored by enforced CD4 T-cell engagement
Haopeng Yang, Wenchao Zhang, Vida Ravanmehr, Kevin Bowman et autres
ABSTRACT: The CREBBP lysine acetyltransferase (KAT) is frequently mutated in follicular lymphoma and diffuse large B-cell lymphoma and has been studied using gene knockout in murine and human cells. However, most CREBBP mutations encode amino acid substitutions within the catalytic KAT domain …
us, fr (code pays fourni par la source)
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Blood
Supplementary Figure 5 from Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma
Joshua P. Plotnik, Adam E. Richardson, Haopeng Yang, Estela Rojas et autres
Antiapoptotic complex formation in ABC-DLBCL xenografts after ABBV-MALT1 monotherapy
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Supplementary Figure 4 from Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma
Joshua P. Plotnik, Adam E. Richardson, Haopeng Yang, Estela Rojas et autres
Efficacy of ABBV-MALT1 across non-GCB PDX models
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Data from Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma
Joshua P. Plotnik, Adam E. Richardson, Haopeng Yang, Estela Rojas et autres
Abstract The activated B cell (ABC) subset of diffuse large B-cell lymphoma (DLBCL) is characterized by chronic B-cell receptor signaling and associated with poor outcomes when treated with standard therapy. In ABC-DLBCL, MALT1 is a core enzyme that is constitutively activated by …
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Supplementary Materials and Methods from Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma
Joshua P. Plotnik, Adam E. Richardson, Haopeng Yang, Estela Rojas et autres
Supplementary Materials and Methods
us (code pays fourni par la source)
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Data from Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma
Joshua P. Plotnik, Adam E. Richardson, Haopeng Yang, Estela Rojas et autres
Abstract The activated B cell (ABC) subset of diffuse large B-cell lymphoma (DLBCL) is characterized by chronic B-cell receptor signaling and associated with poor outcomes when treated with standard therapy. In ABC-DLBCL, MALT1 is a core enzyme that is constitutively activated by …
0 citations
Supplementary File 2 from Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma
Joshua P. Plotnik, Adam E. Richardson, Haopeng Yang, Estela Rojas et autres
Excel Workbook RNASeq
0 citations
Supplementary File 1 from Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma
Joshua P. Plotnik, Adam E. Richardson, Haopeng Yang, Estela Rojas et autres
Excel Workbook ABBV-MALT1 Pharmacology
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Supplementary Figure 7 from Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma
Joshua P. Plotnik, Adam E. Richardson, Haopeng Yang, Estela Rojas et autres
MALT1 and BCL2 inhibition do not antagonize each other in monotherapy sensitive patient derived xenografts
0 citations
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