Ricardo da Cruz Lage

Mapping the extra-Musculoskeletal manifestations in patients with spondyloarthritis: Insights from the Brazilian Registry of Spondyloarthritis (RBE)

Rywka Golebiovski, Gustavo Gomes Resende, Claudia Diniz Lopes Marques, Carla Gonçalves Schahin Saad et autres

The Burden of Spine Structural Damage on Function in Patients With Axial Spondyloarthritis: Adaptation-Mediated Uncoupling?

Marcela Paula Santos Penteado, Gustavo Gomes Resende, Ricardo da Cruz Lage, Wilson Campos Tavares et autres

Objective To investigate the association between spinal damage and functional capacity in patients with axial spondyloarthritis (axSpA) and to compare the performance of 2 radiographic scores (modified Stoke Ankylosing Spondylitis Spine Score [mSASSS] and Combined Ankylosing Spondylitis Spine Score [CASSS]). Methods Radiographs …

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To be or not to B27 positive: implications for the phenotypes of axial spondyloarthritis outcomes. Data from a large multiracial cohort from the Brazilian Registry of Spondyloarthritis

Gustavo Gomes Resende, Carla Gonçalves Schahin Saad, Cláudia Diniz Lopes Marques, Sandra Lúcia Euzébio Ribeiro et autres

BACKGROUND: There is a remarkable variability in the frequency of HLA-B27 positivity in patients with spondyloarthritis (SpA), which may be associated with different clinical presentations worldwide. However, there is a lack of data considering ethnicity and sex on the evaluation of the …

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ROOT JOINT INVOLVEMENT IN SPONDYLOARTHRITIS: DATA FROM A LARGE MULTICENTRIC COHORT

Sandra Lúcia Euzébio Ribeiro, Carla Gonçalves Schahin Saad, Cláudia Diniz Lopes Marques, Gustavo Gomes Resende et autres

BACKGROUNDAlthough root joint involvement (RJI) predicts disease severity in spondyloarthritis (SpA), studies focusing on this involvement are still lacking.This study aimed to determine the prevalence and factors associated with RJI in the Brazilian Registry of SpA (RBE).

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PREVALENCE AND ASSOCIATIONS OF HLA-B27 IN A LARGE MULTIRACIAL COHORT OF THE BRAZILIAN REGISTRY OF SPONDYLOARTHRITIS

Gustavo Gomes Rresende, Carla Gonçalves Schahin Saad, Cláudia Diniz Lopes Marques, Sandra Lúcia Euzébio Ribeiro et autres

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Blockade of interleukin seventeen (IL-17A) with secukinumab in hospitalized COVID-19 patients – the BISHOP study

Gustavo Gomes Resende, Ricardo da Cruz Lage, Samara Quadros Lobê, Amanda Fonseca Medeiros et autres

Background Patients with severe COVID-19 seem to evolve with a compromised antiviral response and hyperinflammation. Neutrophils are critical players in COVID-19. IL-17A plays a major role in protection against extracellular pathogens and neutrophil attraction/activation. We hypothesized that secukinumab, an anti-IL17A monoclonal antibody, …

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Brazilian Society of Rheumatology 2020 guidelines for psoriatic arthritis

Sueli Carneiro, Penélope Esther Palominos, Sônia Maria Alvarenga Anti, Rodrigo Luppino Assad et autres

Psoriatic arthritis (PsA) is a chronic and systemic immune disease characterized by inflammation of peripheral and/or axial joints and entheses in patients with psoriasis (PsO). Extra-articular and extracutaneous manifestations and numerous comorbidities can also be present. These recommendations replace the previous version …

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Blockade of Interleukin Seventeen (IL-17A) with Secukinumab in Hospitalized COVID-19 patients – the BISHOP study

Gustavo Gomes Resende, Ricardo da Cruz Lage, Samara Quadros Lobê, Amanda Fonseca Medeiros et autres

ABSTRACT Background Patients with severe COVID-19 seem to have a compromised antiviral response and hyperinflammation. Neutrophils are critical players in COVID-19 pathogenesis. IL-17A plays a major role in protection against extracellular pathogens and neutrophil attraction and activation. We hypothesized that secukinumab, an …

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Brazilian recommendations for the use of nonsteroidal anti-inflammatory drugs in patients with axial spondyloarthritis

Ricardo da Cruz Lage, Cláudia Diniz Lopes Marques, Thauana Luiza de Oliveira, Gustavo Gomes Resende et autres

Spondyloarthritis (SpA) is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. Over some decades, nonsteroidal anti-inflammatory drugs (NSAIDs) have been the basis for the pharmacological treatment of patients with axial spondyloarthritis …

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AMOUNT OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS INTAKE AND ITS RELATION TO RENAL FUNCTION IN PATIENTS WITH SPONDYLOARTHRITIS: AN 18-YEAR FOLLOW-UP STUDY

Victória Carneiro Dal Moro, Gustavo Gomes Resende, Ricardo da Cruz Lage, Larissa Maria Oliveira Gonzaga et autres

BACKGROUNDNonsteroidal anti-inflammatory drugs (NSAIDs) are still an important tool in the management of spondyloarthritis (SpA), especially axial SpA.Despite the adverse renal effects associated with NSAIDs in other populations, studies describing this potential damage in SpA are lacking.The aim of the present study …

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Disabling and deforming chronic tophaceous gout: is it possible to improve the quality of life and functionality with the treatment available in Brazil? - A case report.

Clarice Moura Mata Machado, Letícia Neves Martins, Matheus Fonseca Cardoso, Rafael Fusaro Aguiar Oliveira et autres

BACKGROUNDGout is a disease caused by the deposition of monosodium urate crystals in joints, bones and soft tissues.It may result in acute arthritis, chronic arthritis and tophaceous gout, with bone erosions and joint destruction.Urate-lowering therapy aims to reach values lower than 6 …

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The Brazilian Society of Rheumatology guidelines for axial spondyloarthritis – 2019

Gustavo Gomes Resende, Eduardo de Souza Meirelles, Cláudia Diniz Lopes Marques, Adriano Chiereghin et autres

Spondyloarthritis is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. The classification axial spondyloarthritis is adopted when the spine and/or the sacroiliac joints are predominantly involved. This version of recommendations replaces …

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