Nadilly Bonagas

The one‐carbon metabolic enzyme MTHFD2 promotes resection and homologous recombination after ionizing radiation

Petra Marttila, Nadilly Bonagas, Christina Chalkiadaki, Hannah Stigsdotter et autres

se, gb (code pays fourni par la source)

Abstract B109: MTHFD1/2 inhibitor TH9619 targets the DNA damage response and causes cancer-specific folate trapping with an unprecedented therapeutic window

Petra Martilla, Alanna C. Green, Nicole Kiweler, Christina Chalkiadaki et autres

se, gb, lu (code pays fourni par la source)

Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells

Alanna C. Green, Petra Marttila, Nicole Kiweler, Christina Chalkiadaki et autres

gb, se, lu, us, dk, es (code pays fourni par la source)

Supplementary Table S2 from Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

Robert Gustafsson, Ann‐Sofie Jemth, Nina Gustafsson, Katarina Färnegårdh et autres

Supplementary Methods and References from Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

Robert Gustafsson, Ann‐Sofie Jemth, Nina Gustafsson, Katarina Färnegårdh et autres

Data from Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

Robert Gustafsson, Ann‐Sofie Jemth, Nina Gustafsson, Katarina Färnegårdh et autres

Supplementary Figures S1-S7 from Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

Robert Gustafsson, Ann‐Sofie Jemth, Nina Gustafsson, Katarina Färnegårdh et autres

Supplementary Table S1 from Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

Robert Gustafsson, Ann‐Sofie Jemth, Nina Gustafsson, Katarina Färnegårdh et autres

Supplementary Methods and References from Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

Robert Gustafsson, Ann‐Sofie Jemth, Nina Gustafsson, Katarina Färnegårdh et autres

Supplementary Table S1 from Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

Robert Gustafsson, Ann‐Sofie Jemth, Nina Gustafsson, Katarina Färnegårdh et autres

Supplementary Table S2 from Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

Robert Gustafsson, Ann‐Sofie Jemth, Nina Gustafsson, Katarina Färnegårdh et autres

Supplementary Figures S1-S7 from Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

Robert Gustafsson, Ann‐Sofie Jemth, Nina Gustafsson, Katarina Färnegårdh et autres