Jun Cui

Imported ocular loiasis in Northeast China: a case report of a morphologically identified adult Loa loa infection Imported Ocular Filariasis: A Clinical Case Report

Lu Yan, Renzhe Cui, Jun Cui, Quan Yuzhu et autres

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Bletilla striata polysaccharides promote the proliferation and migration of human gingival fibroblasts on titanium surfaces via the PI3K/AKT pathway: a preliminary in vitro study

Fengtong Liu, X.C. Li, Rong Rong, Cong Zhou et autres

To investigate the effects of Bletilla striata polysaccharides (BSPs) on the proliferation and migration of human gingival fibroblasts (HGFs) on titanium surfaces and clarify the regulatory role of the PI3K/AKT signaling pathway. Primary HGFs were isolated from healthy gingival tissues and subjected …

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IL-38 attenuates vascular calcification by upregulating GPX3-mediated antioxidant defense via the PPAR-γ/NRF2 axis

Lei Zhu, Qiang Wang, Bin Shang, Jun Cui et autres

Vascular calcification is a pathological process commonly associated with cardiovascular diseases, diabetes, and renal insufficiency, driven by inflammation, oxidative stress, and endoplasmic reticulum stress. IL-38, a member of the IL-1 cytokine family, has shown anti-inflammatory, antioxidant, and anti-fibrotic effects in cardiovascular contexts. …

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Integrated multi-omics analysis reveals key hub genes and mechanisms in calcific aortic stenosis

Fengxia Wang, Shuai Liu, Haijiang Guo, Jie Yu et autres

Objective Aortic stenosis (AS) is a critical risk factor for the development of structural heart disease, and identifying its pathogenic genes will provide new insights into cardiac pathology and treatment. Methods “edgeR” was used to calculate differentially expressed genes (DEGs) for bulk-RNAseq. …

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Stromal cell‐derived factor‐1 regulates expression of vascular endothelial growth factor and osteopontin after tooth extraction

Jingjing Kong, Lei Li, Fei Gao, Kaiqi Zhang et autres

BACKGROUND: The present study aimed to investigate the expression of stromal cell-derived factor-1 (SDF-1) after tooth extraction in rats and its regulatory effect on the expression of osteopontin (OPN) and vascular endothelial growth factor (VEGF). METHODS: The first mandibular molar of the …

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[Clinical and genetic characteristics of fibrocalculous pancreatic diabetes associated with SPINK1 gene mutations in a patient with type 1 diabetes].

Wenli Zhao, Hao Wang, Benjamin J. Huang, Shouwei Li et autres

To investigate the pathogenic mechanisms of a patient with type 1 diabetes mellitus (T1DM) complicated with fibrocalculous pancreatic diabetes at Tianjin Medical University General Hospital Airport Site in June 2024, clinical and genetic characteristic analyses were performed. Potential pathogenic genes were screened …

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Effect of kaempferol from Acori Tatarinowii Rhizoma (ATR) on grass carp (Ctenopharyngodon idella) infected with Aeromonas hydrophila

Jun Cui, Qin Fan, Ze-Wei Zhao, Yibo Hu et autres

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Repurposing pharmaceuticals for Alzheimer's treatment via adjusting the lactoferrin interacting proteins

Xin Liu, Jun Cui, Yun Li, Xin Tong et autres

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Combining network pharmacology and molecular docking to explore the pharmacological mechanism of Codonopsis Radix.-Hedysarum Multijugum Maxim.-Atractylodes Macrocephala Koidz. in treating lung cancer

Bin He, Jun Cui, Zengwang Zhang, Yongjun Zhang

AIM: To explore the potential mechanism of the treatment of lung cancer (LC) with Codonopsis Radix.-Hedysarum Multijugum Maxim.-Atractylodes Macrocephala Koidz. (CHA). METHODS: The active ingredients and targets of CHA were obtained from TCMSP and SwissTargetPrediction databases. LC-related genes were obtained from MalaCards, …

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Expression, Interferon-γ of Takifugu rubripes in Pichia pastoris

Derong Kong, Zhicheng Wang, Jun Cui, Hui Li et autres

Interferon gamma (IFN-γ), a major cytokine, has broad-spectrum antiviral function, in addition to play a key role in the process of immune regulation. In this study, in order to explore the biological roles of recombinant IFN-γ (rIFN-γ), IFN-γ was cloned from Takifugu …

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Transcript Sequencing in Sea Cucumber (Apostichopus japonicus)

Xiaoxu Zhou, Jun Cui, Xuemei Qiu, Yaqing Chang et autres

As the efficient genomic resources, molecular markers (single nucleotide polymorphism (SNPs) and simple sequence repeats (SSRs)) have become the significant molecular marker of choice for breeding programs and population genetic studies in many species.RNA-Seq has been approved as a cost-effective and efficient …

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Correlation Between Effector Gene Expression Targeted by lncRNAs in the Oomycete Fish Pathogen, Saprolegnia parasitica

Lijuan Liao, Zihao Zhao, Yibo Hu, Ziquan Yu et autres

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