K. F. Bodmann

Kalkulierte parenterale Initialtherapie bakterieller Infektionen: Bakterielle Endokarditis

Pascal M. Dohmen, K. F. Bodmann, Wolfgang Graninger, PRAMOD M. SHAH et autres

updated version. The German guideline by the Paul-Ehrlich-Gesellschaft für Chemotherapie e.V. (PEG) has been translated to address an international audience. The bacterial endocarditis is characterised by a constant incidence but a shift in the patient population due to the use of prosthetic …

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Clinical efficacy of tigecycline used as monotherapy or in combination regimens for complicated infections with documented involvement of multiresistant bacteria

Wolfgang R. Heizmann, Peter Andreas Löschmann, Christian Eckmann, Christof von Eiff et autres

INTRODUCTION: Tigecycline is an established treatment option for infections with multiresistant bacteria (MRB). It retains activity against many strains with limited susceptibility to other antibiotics. Efficacy and safety of tigecycline as monotherapy or in combination regimens were investigated in a prospective noninterventional …

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Resistance mechanisms and epidemiology of multiresistant pathogens in Europe and efficacy of tigecycline in observational studies

Wolfgang R. Heizmann, Herbert L. DuPont, Philippe Montravers, Xavier Guirao et autres

OBJECTIVES: Antimicrobial drug resistance is a growing problem in Europe and, even with differences in epidemiology, it is of great concern. The treatment of complicated skin and soft-tissue infections (cSSTIs) and complicated intra-abdominal infections (cIAIs) is hindered further by pathogens that are …

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Safety and tolerability of tigecycline for the treatment of complicated skin and soft-tissue and intra-abdominal infections: an analysis based on five European observational studies

Xavier Guirao, Miguel Sánchez García, Matteo Bassetti, K. F. Bodmann et autres

OBJECTIVES: Tigecycline is approved for the treatment of complicated skin and soft-tissue infections (cSSTIs) and complicated intra-abdominal infections (cIAIs) in adults. In this analysis the safety and tolerability profile of tigecycline (used alone or in combination) for the treatment of patients with …

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Efficacy of tigecycline for the treatment of complicated intra-abdominal infections in real-life clinical practice from five European observational studies

Christian Eckmann, Philippe Montravers, Matteo Bassetti, K. F. Bodmann et autres

OBJECTIVES: Tigecycline is a broad-spectrum antibiotic approved for the treatment of complicated intra-abdominal infections (cIAIs). The efficacy of tigecycline when administered as monotherapy or in combination with other antibacterials in the treatment of cIAIs in routine clinical practice is described. PATIENTS AND …

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Prescription behaviours for tigecycline in real-life clinical practice from five European observational studies

Matteo Bassetti, Christian Eckmann, K. F. Bodmann, Herbert L. DuPont et autres

OBJECTIVES: There is limited information on the use of tigecycline in real-life clinical practice. This analysis aims to identify and understand tigecycline prescribing patterns and associated patient outcomes for approved indications. PATIENTS AND METHODS: A pooled analysis of patient-level data collected on …

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Efficacy of tigecycline for the treatment of complicated skin and soft-tissue infections in real-life clinical practice from five European observational studies

Philippe Montravers, Matteo Bassetti, Herve Tissot Dupont, Christian Eckmann et autres

OBJECTIVES: Tigecycline is an approved treatment for complicated skin and soft-tissue infections (cSSTIs). The efficacy of tigecycline as monotherapy or in combination with other antibacterials in the treatment of cSSTI in routine practice is described. PATIENTS AND METHODS: Individual patient-level data were …

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Perioperatives Monitoring Teil 1

P. Hanfland, K. F. Bodmann, H.-P. Schüster, P. Jürgens et autres