Ferenc Pintér

Internationaler Känguru-Mathematikwettbewerb

Frida Grundmann Pintér, Ferenc Pintér

Wir präsentieren den Internationalen Känguru-Mathematikwettbewerb, der in Ungarn von der Stiftung für Mathematische Talente (MaTe-Stiftung) organisiert wird. Der Wettbewerb findet jedes Jahr am dritten März-Donnerstag in einem Multiple-Choice-Testformat statt. Der Wettbewerb wird in mehr als 80 Ländern mit mehr als 6 Millionen …

Large-Scale Terrain Rendering for Outdoor Games

Ferenc Pintér

Visualizing large scale landscapes on current generation consoles is a challenging task, because of the restricted amount of memory and processing power compared with high-end personal computers. This chapter describes limitations and deals with the different content creation, rendering, and performance issues. …

Anomalous equivalent potential temperature: an atmospheric feature predicting days with higher risk for fatal outcome in acute ischemic stroke—a preliminary study

András Folyovich, Dávid Biczó, Nadim Al‐Muhanna, Anna K. Béres‐Molnár et autres

hu (code pays fourni par la source)

Major partial response to crizotinib, a dual MET/ALK inhibitor, in a squamous cell lung (SCC) carcinoma patient with de novo c-MET amplification in the absence of ALK rearrangement

Richárd Schwab, István Peták, Mihaly Kollar, Ferenc Pintér et autres

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Effectiveness of erlotinib in lung adenocarcinomas with classic and alternative EGFR mutations detected by Roche 454 GS-FLX next-generation sequencing (NGS).

Gyula Ostoros, Veronika Sárosi, László Mándoky, Ferenc Pintér et autres

e19090^ Background: Next generation sequencing (NGS) detects all possible mutations with a higher sensitivity than Sanger sequencing. EGFR mutations are important predictors of sensitivity and resistance to EGFR tyrosine kinase inhibitors including erlotinib. The clinical significance of alternative (“rare”) EGFR mutation types, …

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HeurAA: Accurate and Fast Detection of Genetic Variations with a Novel Heuristic Amplicon Aligner Program for Next Generation Sequencing

Lőrinc Sándor Pongor, Ferenc Pintér, István Peták

Next generation sequencing (NGS) of PCR amplicons is a standard approach to detect genetic variations in personalized medicine such as cancer diagnostics. Computer programs used in the NGS community often miss insertions and deletions (indels) that constitute a large part of known …

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Epidermal growth factor receptor signalling contributes to osteoblastic stromal cell proliferation, osteoclastogenesis and disease progression in giant cell tumour of bone

Péter Balla, Linda Moskovszky, Zoltàn Sápi, Ramses Forsyth et autres

Balla P, Moskovszky L, Sapi Z, Forsyth R, Knowles H, Athanasou N A, Szendroi M, Kopper L, Rajnai H, Pinter F, Petak I, Benassi M S, Picci P, Conti A & Krenacs T(2011) Histopathology59, 376–389 Epidermal growth factor receptor signalling contributes to …

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Epidermal Growth Factor Receptor (EGFR) High Gene Copy Number and Activating Mutations in Lung Adenocarcinomas Are Not Consistently Accompanied by Positivity for EGFR Protein by Standard Immunohistochemistry

Ferenc Pintér, Judit Pápay, Andrea Almási, Zoltàn Sápi et autres

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Biochemical Assay-Based Selectivity Profiling of Clinically Relevant Kinase Inhibitors on Mutant Forms of EGF Receptor

Edit Várkondi, Ferenc Pintér, Róbert Kiss, Richárd Schwab et autres

Gefitinib and erlotinib are potent EGFR tyrosine kinase inhibitors (potentially) useful for the treatment of non-small-cell lung cancer (NSCLC). Clinical responses, however, in NSCLC patients have been linked to the presence of certain activating mutations of EGFR. We used an ELISA-based biochemical …

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[Epidermal growth factor receptor (EGFR): therapeutic target in the treatment of lung adenocarcinoma].

Richárd Schwab, István Peták, Ferenc Pintér, Edit Szabó et autres

Revolution in biotechnology made possible to identify those gene errors, which via their encoded proteins (mostly kinase enzymes) are key players in tumor development, growth and progression, and could be considered as molecular targets in tumor diagnosis and therapy. Activity of EGFR …

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Modern Treatment of Lung Cancer

Richárd Schwab, Ferenc Pintér, Judit Moldavy, J. Pápay et autres

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Early diagnosis of pancreatobiliary duct malignancies by brush cytology and biopsy

Gábor Elek, T Gyökeres, E. L. Schäfer, M Burai et autres

hu (code pays fourni par la source)