Accès ouvert
2026
article
OpenAlex
Meike Höhl, Miriam Rengel, Michael Marks, Stefan Größ et autres
Abstract The P2X7 receptor (P2X7R) is an ATP-gated cation channel that plays an important role in inflammatory signaling, cancer progression, and immune regulation. Yet pharmacological tools that enable direct visualization of P2X7 receptor (P2X7R) expression in live biological systems remain limited. We …
de, jp
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Accès ouvert
2026
article
OpenAlex
Masaya Hagai, Sun J, Lee Jh, Kazuhiro J. Fujimoto et autres
ABSTRACT Thermally activated delayed fluorescence (TADF) emitters enable color‐pure, energy‐efficient organic light‐emitting diodes (OLEDs), yet many ultra‐narrowband designs rely on synthetically demanding boron incorporation. Here we discover boron‐free emitters that reconcile a robust nitrogen‐only polycyclic scaffold, Rec. 2020‐grade pure‐blue emission, and small …
jp
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Masaya Hagai, Sun J, Lee Jh, Kazuhiro J. Fujimoto et autres
ABSTRACT Thermally activated delayed fluorescence (TADF) emitters enable color‐pure, energy‐efficient organic light‐emitting diodes (OLEDs), yet many ultra‐narrowband designs rely on synthetically demanding boron incorporation. Here we discover boron‐free emitters that reconcile a robust nitrogen‐only polycyclic scaffold, Rec. 2020‐grade pure‐blue emission, and small …
jp
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Natsumi Fukaya, Soichiro Ogi, Masayasu Taki, Shigehiro Yamaguchi
Supramolecular polymerization within living cells has emerged as a promising strategy for controlling cellular functions. Lipid droplets, intracellular organelles mainly composed of neutral lipids, provide low-polarity environments, yet their role in regulating supramolecular assembly pathways remains unclear. Here we show that triolein, …
jp
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Accès ouvert
2026
article
OpenAlex
Masahito Murai, Shohei Kamegai, Keita Andoh, Shigehiro Yamaguchi
Metal-free ionic liquids that exhibit intense fluorescence in the visible region of over 500 nm in the fluid state remain scarce. Although small π-conjugated frameworks combining electron-donating and electron-accepting groups represent a promising structural motif, such modifications often lead to fluorescence quenching …
jp
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Accès ouvert
2026
article
OpenAlex
Shun-suke Kanai, Hiroyoshi Fujioka, Minoru Kawatani, Spencer J. Spratt et autres
9-Cyanopyronin derivatives have been used as resonance Raman probes for highly sensitive and multiplexed vibrational biological imaging. Here, we synthesized a series of fourteen 9-cyanopyronin derivatives in which the 10th core atom is substituted with various group 13, 14, 15 or 16 …
jp
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Accès ouvert
2025
article
OpenAlex
Lena Lezius, Elena S. Horst, Maximilian Scherübl, Jessika Lammert et autres
Zusammenfassung Arine sind vielseitige Bausteine in der organischen Chemie. Im Gegensatz zu ihrer umfassend untersuchten ionischen Reaktivität sind radikalische Reaktionen mit Arinen noch kaum erforscht. Wir stellen hier eine neue radikalische Anellierungsreaktion von stabilen Blatter‐ und Verdazyl‐Radikalen mit Arinen vor, die Zugang …
de, jp
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Lena Lezius, Elena S. Horst, Maximilian Scherübl, Jessika Lammert et autres
Arynes are versatile building blocks in organic chemistry. In contrast to their extensively examined ionic reactivity, radical reactions with arynes remain scarcely explored. In this study, we present a novel radical annulation reaction of stable Blatter and verdazyl radicals with arynes, which …
de, jp
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Accès ouvert
2025
preprint
OpenAlex
Soichiro Ogi, Keiji Kajiwara, Natsumi Fukaya, Masayasu Taki et autres
Lipid droplets (LDs) are vital organelles that govern energy storage and lipid metabolism in cells. The ability to direct the self-assembly of small molecules into defined nanostructures within LDs would provide opportunities to modulate their functions. Although supramolecular polymerization has been extensively …
jp
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Accès ouvert
2025
article
OpenAlex
Linawati Sutrisno, Gary J. Richards, Jack D. Evans, Michio Matsumoto et autres
Early detection and late-stage cell fate assessment are key factors to develop therapeutic strategies, although current methods cannot capture early responses or distinguish multiple injury states, especially in ultraviolet-visible (UV-vis)–sensitive cells. Here, we introduce a method to simultaneously detect variations in RNA …
jp, au
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Accès ouvert
2025
preprint
OpenAlex
Tatsuya Mori, Sano Yoshiharu, Tomoyuki Ikai, Yuuya Kawasaki et autres
Reversible coordination bonds between boron and heteroatoms endow boron-based π-conjugated frameworks with dynamic functionality, as interconversion between tri- and tetracoordinate boron centers induces pronounced changes in both molecular geometry and electronic structure. In this study, we synthesized a series of chiral boron-embedded …
jp
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2025
article
OpenAlex
Junwei Wang, Keiji Kajiwara, Manish Kesherwani, Florence Tama et autres
Lipid droplets (LDs) are dynamic organelles essential to lipid metabolism and energy homeostasis, yet their compositional heterogeneity in living cells remains poorly understood. Here, we present LipiPB Red, a red-emissive fluorescent probe with exceptional photostability, high polarity sensitivity, and long-term retention within …
jp, us
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