Magnus Unemo

From silos to synergies: harnessing the power of sexual health data sources in England to understand changing epidemiology and inform policy

Dana Ogaz, Anika Knüppel, Emily Trickett, Soazig Clifton et autres

OBJECTIVES: Following major changes to sexual health provision in England in the past decade, monitoring and evaluation of population-level interventions require re-examination to ensure quality and visibility of key communities. We make the case that sexual health data sources might be used …

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Dramatic Increase of Congenital Syphilis in Hungary—Imperative National Public Health and Laboratory-Based Actions are Under Implementation

Eszter Balla, Fruzsina Petrovay, Timea Tisza, Magnus Unemo

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Extensively drug-resistant (XDR) Neisseria gonorrhoeae cured with ceftriaxone 2 g intravenous monotherapy in Croatia, March 2026

Tajana Juzbašić, Tatjana Nemeth Blažić, Nilia Volarević, Ivana Bešlić et autres

In early 2026 in Croatia, a male heterosexual patient of Croatian origin was diagnosed with extensively drug-resistant (XDR) gonorrhoea after unprotected vaginal intercourse with a Croatian female. The Neisseria gonorrhoeae HR027 isolate (genomic lineage B, MLST sequence type (ST)9903) exhibited high-level azithromycin, …

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Fatty acids-based compounds as novel prophylaxis or treatment for oropharyngeal Neisseria gonorrhoeae: an in vitro study

Syed Ameer Hamza, Rita Paolini, C harlie Moore, Magnus Unemo et autres

(NG) strains in a validated oropharyngeal model. Five oropharyngeal cell lines (tonsillar/buccal/gingival/floor of mouth/uvular) were infected with two NG strains. Intracellular infection was assessed at 15/30/60 min. MIC₉₀ and cytotoxicity of five arginine-based fatty acids were determined. Promising candidates were evaluated for …

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Complete reference genomes of Haemophilus ducreyi isolates ITG3105, CIP76118, and TMA3542, using Oxford Nanopore and Illumina sequencing

Daniel Golparian, Daniel Schröder, Magnus Unemo

ABSTRACT We report the complete reference genome sequences of three Haemophilus ducreyi isolates (ITG3105, CIP76118, and TMA3542), generated using Oxford Nanopore and Illumina sequencing, and hybrid assemblies. Each genome has a closed circular chromosome; ITG3105 and TMA3542 also have plasmids. These reference …

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Evolving global sexually transmitted infection guidance: translating evidence-based WHO recommendations into clinical practice

Ismael Maatouk, Daniel McCartney, Teodora Wi, Francis Ndowa et autres

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Prevalence and correlates of active syphilis diagnosed using serological assays and the molecular research-use-only Aptima Treponema pallidum assay among pregnant women in Zambia, 2023

Elena Shipitsyna, Sumire Sorano, Daniel Schröder, Enesia Banda Chaponda et autres

Introduction Syphilis is a leading cause of adverse pregnancy outcomes, excessively affecting sub-Saharan Africa. Early diagnosis and treatment are crucial to prevent mother-to-child transmission. The aims of the present study were to assess prevalence and epidemiological and clinical correlates of active syphilis …

se, ru, gb, jp, Zambie, am, kr, it, be, ch (code pays fourni par la source)

P2.021 Prevalence of Sexually Transmitted Infections in Young People in St. Petersburg, Russia, as Determined Using Self-Collected Non-Invasive Specimens

Elena Vasilyevna Shipitsyna, Tatiana А. Khusnutdinova, Olga Sergeyevna Ryzhkova, Anna А. Krysanova et autres

Background Young people are worldwide a risk group for sexually transmitted infections (STIs) and a primary target for screening. Knowledge on STI prevalence in the youths is essential to elaborate preventive measures. Self-sampling has been shown to be an effective approach in …

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P2.062 Optimizations and Quality Assurance of the Laboratory Diagnosis and Treatment of Sexually Transmitted Infections in Belarus

О. В. Панкратов, I. G. Shimanskaya, A Lukyanau, Magnus Unemo et autres

Background In 2007–2008, a questionnaire-based study evaluated the quality of the 316 State laboratory services that were engaged in diagnosis of STIs in Belarus. This comprehensive survey clearly demonstrated that many of the tests and testing algorithms used in the laboratory diagnosis …

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P3.083 Is the Syphilis Incidence Decreasing in Georgia?

George Galdava, O Kvlividze, Magnus Unemo, М Домейка

Background The epidemiology of syphilis in Georgia has traditionally been determined by socio-economic factors such as low solvency of Georgian population, urban migration, level of financing of STI prevention programmes etc. This study reports on the epidemiology of syphilis in Georgia over …

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P5.067 The Way to Go Forward in Optimization of STI Management in Eastern Europe: Eastern European Network For Sexual and Reproductive Health (EE SRH)

М Домейка, R C Ballard, Magnus Unemo

Background The collapse of the Soviet Union resulted in large changes in the organisation of the health care in many newly independent countries belonging to the WHO European region. Unfortunately, STI management received a highly suboptimal attention. Accordingly, existing professional STI networks …

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P3.327 Surveillance and Control of Sexually Transmitted Infections in Lithuania

O Ivanauskiene, G Kligys, Rita Butylkina, Staffan Sylvan et autres

Background The contemporary national epidemiological surveillance system of sexually transmitted infections in Lithuania was legalised in 2009. A national computerised reporting system has been introduced, aiming to standardise the data collection and analysis for all communicable diseases and their etiological agents through …

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