Sallwa M. Alshehre

A Retrospective Cohort Study of Uterine Cancer Epidemiological Analysis and Age-Based Disparities in Saudi Arabian Population across 32 Years

Sallwa M. Alshehre, Mohammad A. Althubiti

Objectives: To investigate the burden of uterine tumour in Saudi Arabia during the past 32 years (1990-2021), with an emphasize on the prevalence, incidence, mortality, and disability-adjusted life years (DALYs). Knowing these patterns strengthen the national aims of cancer control under Kingdom …

sa (code pays fourni par la source)

Targeting oxidative stress, inflammation, and apoptosis: The protective role of desloratadine against vancomycin-induced testicular toxicity via the SIRT1/Nrf2/NF-κB axis

Sallwa M. Alshehre, Naeem F. Qusty, Bayan T. Bokhari, Bodour S. Rajab et autres

sa, Égypte (code pays fourni par la source)

In Silico Study of Innovative Compounds Targeting Protein (Survivin): Understandings into Cancer Therapeutics

Abdullah Hamadi, Fawzyah Obeedallah Albaldi, Sallwa M. Alshehre, Ali Mahzari

Background: Survivin, also known as Baculoviral Inhibitor of Apoptosis Repeat Containing 5 (BIRC5), is a key protein involved in cell division and the inhibition of apoptosis, making it an essential component of eukaryotic cell biology. Survivin is highly expressed across all human …

sa (code pays fourni par la source)

Enhanced hepatoprotective effects of empagliflozin and vitamin D dual therapy against metabolic dysfunction‐associated steatohepatitis in mice by boosted modulation of metabolic, oxidative stress, and inflammatory pathways

Wesam F. Farrash, Shakir Idris, Mohamed Elzubier, Elshiekh B. Khidir et autres

Abstract Although single treatment with sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) or vitamin D3 (VD3) inhibited metabolic dysfunction‐associated steatohepatitis (MASH) development in diabetic patients, their combination has not been explored previously. Hence, this study investigated the hepatoprotective effects of SGLT2i (empagliflozin) and/or VD3 against …

sa, Égypte (code pays fourni par la source)

CONTROLLED TRIAL TO INVESTIGATE THE EFFECT OF ENDOMETRIOSIS ON THE HUMAN FOLLICULAR FLUID (HFF) MICROENVIRONMENT USING SHOTGUN PROTEOMICS FOR PATIENTS UNDERWENT FERTILITY TECHNIQUES

Sallwa M. Alshehre

Key Disease-Related Genes and Immune Cell Infiltration Landscape in Inflammatory Bowel Disease: A Bioinformatics Investigation

Kawthar Saad Alghamdi, Rahaf H. Kassar, Wesam F. Farrash, Ahmad A. Obaid et autres

Inflammatory Bowel Diseases (IBD), which encompass ulcerative colitis (UC) and Crohn’s disease (CD), are characterized by chronic inflammation and tissue damage of the gastrointestinal tract. This study aimed to uncover novel disease-gene signatures, dysregulated pathways, and the immune cell infiltration landscape of …

sa, my (code pays fourni par la source)

The impact of endometrioma on in vitro fertilisation/intra-cytoplasmic injection IVF/ICSI reproductive outcomes: a systematic review and meta-analysis

Sallwa M. Alshehre, Brenda F. Narice, Mark A. Fenwick, Mostafa Metwally

BACKGROUND: Assisted reproductive technologies (ART) such as in vitro fertilisation (IVF) and intra-cytoplasmic sperm injection (ICSI) are often used to aid fertility in women with endometrioma; however, the implications of endometrioma on ART are unresolved. OBJECTIVE: To determine the effect of endometrioma …

sa, gb (code pays fourni par la source)

A prospective, single-centre, single-arm, open label study of the long term use of a gonadotropin releasing hormone agonist (Triptorelin SR, 11.25 mg) in combination with Tibolone add-back therapy in the management of chronic cyclical pelvic pain

Sallwa M. Alshehre, Sheila Duffy, Georgina Jones, Mostafa Metwally

BACKGROUND: Chronic cyclic pelvic pain (CCPP) affects women's quality of life and pituitary downregulation is often used for symptomatic relief. However, prolonged suppression of ovarian function is associated with menopausal side effects and can lead to osteoporosis. Currently, the use of gonadotropin …

gb, au (code pays fourni par la source)