Teresa Zhang

Axicabtagene ciloleucel in combination with rituximab for refractory large B cell lymphoma: the phase 2, single-arm ZUMA-14 trial

Paolo Strati, Lori Ann Leslie, Parveen Shiraz, Lihua Elizabeth Budde et autres

CD19-negative relapse occurs in ~30% of persons with relapsed or refractory large B cell lymphoma (LBCL) who respond to axicabtagene ciloleucel (axi-cel; CD19-directed chimeric antigen receptor (CAR) T cell therapy). In this phase 2 single-arm study, 26 participants with chemorefractory LBCL received …

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Resident and Physician Assistant Co-management—One Model for Reducing Inequities in Care for Patients with Diabetes

Alev J Atalay, Christina Meade, Bonnie Southworth, Rick Gitomer et autres

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Tocilizumab Prophylaxis Following Axicabtagene Ciloleucel in Relapsed or Refractory Large B-Cell Lymphoma

Frederick Lundry Locke, Sattva Swarup Neelapu, Nancy L. Bartlett, Lazaros J. Lekakis et autres

cells/kg) on d 0. Prophylactic tocilizumab (8 mg/kg) was administered 48 h after axi-cel infusion. Primary endpoints were incidence and severity of CRS and NEs. Key secondary endpoints included the incidence of adverse events, objective response rate (ORR), duration of response, progression-free …

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A first-in-human phase 1a dose-escalation study of BGB-15025 (HPK1 inhibitor) as monotherapy and in combination with tislelizumab (TIS; anti-PD-1 antibody) in patients (pts) with advanced solid tumors.

Sanjeev Deva, Caicun Zhou, Sarwan K. Bishnoi, Peter K. H. Lau et autres

2585 Background: Hematopoietic progenitor kinase 1 (HPK1), a critical negative feedback regulator of T-lymphocyte and dendritic cell activation, is a potential target for IO treatment (tx). BGB-15025, a potent, selective, small-molecule HPK1 inhibitor, showed preliminary antitumor effects in preclinical studies as monotherapy …

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Impact of ambulatory co‐management on medicine resident training

Christina Meade, Teresa Zhang, Richard S. Gitomer, Bonnie Southworth et autres

Circulating long non-coding RNAs as biomarkers of acute myocardial infarction

Qiying Dai, José Paulo Freire, Teresa Zhang

Abstract: For the past decades, acute myocardial infarction (AMI) has been the most common cause of death in both genders. The invention of percutaneous intervention (PCI) has saved thousands of lives. The most important prognostic factor for AMI is the time between …

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