Benjamin Edward Smith

Effect of Prebiotic Supplementation With and Without Physiotherapy on Pain and Pain Sensitivity in People with Knee Osteoarthritis

Afroditi Kouraki, S.J. Franks, Amrita Vijay, Thomas Kurien et autres

Background: Emerging evidence links the gut microbiome to chronic pain processing. Inulin, a prebiotic fibre, modulates the gut microbiome, while physiotherapy-supported exercise (PSE) improves pain and function. We evaluated the effects of inulin supplementation with and without PSE on knee osteoarthritis (OA) …

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Assessment and maintenance of normal fluid status in older people living in care homes: a scoping review protocol

Catherine Fielding, Sevim Y. Hodge, Eleanor Lunt, Gerri Mortimore et autres

INTRODUCTION: Maintaining normal fluid status is critical to health and well-being. Older people are vulnerable to abnormal fluid status and associated complications, morbidity and mortality. Care home residents are especially vulnerable due to dependence on care home staff, frailty and multiple comorbidities. …

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Use of a shared decision-making intervention to support treatment decision-making for patients following an anterior cruciate ligament rupture: a mixed methods feasibility study

Hayley M. Carter, David John Beard, Charlotte Dodsley, Paul A. Leighton et autres

OBJECTIVES: To understand feasibility, acceptability and indicators of effectiveness of a shared decision-making (SDM) intervention with patients following an anterior cruciate ligament (ACL) rupture. DESIGN: Non-randomised feasibility study with embedded qualitative interviews. SETTING: Orthopaedic and physiotherapy service at an acute National Health …

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Adverse Outcome Pathway on Deposition of Energy Leading to Cataracts

Emma Carrothers, Meghan Appleby, Vita Lai, Tatiana Kozbenko et autres

The present Adverse Outcome Pathway (AOP) describes the development of cataracts following ionizing radiation exposure, beginning with the deposition of energy into cells of the eye. This event generates an excess of reactive oxygen species, leading to oxidative stress when the balance …

Adverse Outcome Pathway on Deposition of Energy Leading to Learning and Memory Impairment

Ahmad Sleiman, Kathleen B. Miller, Danicia Flores, Jacqueline Kuan et autres

The present Adverse Outcome Pathway (AOP) describes the linkage between cognitive decline, including learning and memory impairment, initiated by the Deposition of Energy (DoE) from ionizing radiation in the central nervous system. Ionizing radiation causes an excess of reactive oxygen species (ROS), …

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Effectiveness of Painful Versus Nonpainful Exercise on Pain Intensity, Disability, and Other Patient-Reported Outcomes in Adults With Chronic Musculoskeletal Pain: An Updated Systematic Review With Meta-Analysis

Ivy Tran, Mitchell T. Gibbs, Ning Yu, Jared K. Powell et autres

OBJECTIVE: The purpose of this study was to determine the effect of painful versus nonpainful exercise on pain, disability, and other patient-reported outcomes in adults with chronic musculoskeletal pain. DESIGN: This study is an intervention systematic review with meta-analysis. LITERATURE SEARCH: Electronic …

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Effectiveness of a community-based rehabilitation programme following hip fracture: results from the Fracture in the Elderly Multidisciplinary Rehabilitation phase III (FEMuR III) randomised controlled trial

Nefyn Howard Williams, Monica E Busse, Rachael Cooper, Susanna R. Dodd et autres

OBJECTIVE: To determine whether an enhanced community rehabilitation intervention (the Fracture in the Elderly Multidisciplinary Rehabilitation (FEMuR) intervention) was more effective than usual National Health Service care, following surgical repair of hip fracture, in terms of the recovery of activities of daily …

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“My bloody leg” – the lived experience of arthrofibrosis and manipulation under anaesthetic following total knee arthroplasty

Fiona Moffatt, Melanie Jay Narayanasamy, Joanne Stocks, Benjamin Edward Smith et autres

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Development of an intervention for patients following an anterior cruciate ligament rupture: an online nominal group technique consensus study

H. Carter, David John Beard, Paul A. Leighton, Fiona Moffatt et autres

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Non-surgical interventions for arthrofibrosis following knee joint replacement: A systematic review

Michelle Hall, Benjamin Edward Smith, Katie Jane Sheehan, Stefanny Guerra et autres

ObjectiveTo evaluate the effectiveness of non-surgical interventions for knee stiffness or arthrofibrosis following knee replacement surgery.Data sourcesOvid MEDLINE, Ovid Embase, Cochrane Central Register of Controlled Trials (CENTRAL), and Cumulative Index to Nursing and Allied Health Literature (CINAHL)were searched from database inception to …

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14 Use of a shared decision-making intervention to support treatment decision-making following an anterior cruciate ligament rupture: a mixed-methods feasibility study

Hayley M. Carter, David John Beard, Charlotte Dodsley, Paul A. Leighton et autres

Introduction This study aimed to understand feasibility, acceptability and indicators of effectiveness of a shared decision-making (SDM) intervention with patients following an anterior cruciate ligament (ACL) rupture in a UK NHS setting.Materials and Methods A non-randomised feasibility study with embedded qualitative interviews …

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‘Going through the motions’; a rich account of the complexity of the anterior cruciate ligament reconstruction pathway, a UK qualitative study

Hayley M. Carter, David John Beard, Paul A. Leighton, Fiona Moffatt et autres

OBJECTIVES: This study aimed to understand the lived experiences of patients on the anterior cruciate ligament reconstruction (ACLR) pathway up to 3 months before, 3 months after and 1 year after surgery. Study objectives were to explore (1) patient experiences of preoperative …

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