Rongqian Wu

Bloodstream infection in patients with pyogenic liver abscess: Predictors, microbiological characteristics, and in-hospital outcomes

Yi Fan, Jun Hai, Lintao Chen, Ligang Nan et autres

OBJECTIVES: To investigate the predictors, microbiological characteristics, and in-hospital outcomes of bloodstream infection (BSI) in patients with pyogenic liver abscess (PLA). METHODS: We conducted a retrospective single-center cohort study of patients with PLA who underwent blood culture testing during hospitalization between January …

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Scorpion venom as a source of new antimicrobial agents

Yuanyuan Zhang, Rongqian Wu

The escalating global threat of antimicrobial resistance necessitates urgent discovery of novel therapeutic agents. Scorpion venom, a complex cocktail of bioactive molecules, has emerged as a promising reservoir of antimicrobial peptides (AMPs) with potent activity against multidrug-resistant pathogens. This review comprehensively examines …

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Uniform and Complete Irreversible Electroporation on Mucosa Enabled by Sintered Silver Hydrogel

Zhuoqun Li, Shenshen Lei, Quanpeng Li, Fulai Lin et autres

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Crosstalk‐Mitigated OAM Recovery Through Strong Scattering via Sparsity‐Regularized LG‐TM

Guangdong Ma, Shupeng Zhao, Xiao Wang, Min An et autres

ABSTRACT Light beams carrying orbital angular momentum (OAM) provide an unbounded set of mutually orthogonal spatial modes, enabling high‐dimensional information encoding for optical communication and sensing. However, strong scattering severely distorts the helical phase structure of OAM beams, introducing inter‐modal crosstalk that …

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Association between prognostic nutritional index and clinical outcomes in patients with pyogenic liver abscess: a retrospective multicenter study

Jianguo Wang, Zhenyi Lin, Lintao Chen, zi Yang et autres

BACKGROUND & AIMS: Despite advances in therapeutic strategies, pyogenic liver abscess (PLA) remains a life-threatening bacterial infection associated with substantial mortality. The Prognostic Nutritional Index (PNI), a marker of immuno-nutritional status, has been shown to predict outcomes in various diseases. However, its …

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(Fe 4 N/GaN)@GC: A Bifunctional Electrocatalyst for High‐Performance Rechargeable Zinc‐Air Batteries

Xin‐Yuan Wei, Sai‐Sai Xie, Xia‐Li Ding, Yuan‐Qi Zhai et autres

ABSTRACT Rechargeable zinc‐air batteries (ZABs), though offering a high theoretical energy density (1086 Wh kg −1 ) and intrinsic nonflammability, require efficient electrocatalysts for oxygen reduction reaction (ORR) and oxygen evolution reaction (OER). At present, state‐of‐the‐art electrocatalysts for ORR and OER are …

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Study on Optimal Optical Parameters for Cutting Liver Tissue with a Novel 980/1470 nm Dual-Wavelength Semiconductor Laser

Yiwen Lu, G X Liu, Kuiyuan Chai, Zien Xu et autres

Purpose: Laser–tissue interactions induce photothermal effects governed by wavelength-dependent absorption and circulation of energy. While 980 nm targets hemoglobin for hemostasis and 1470 nm targets water for vaporization, their synergistic optimization in living liver tissue remains undefined, as existing studies predominantly examine …

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SUMOylation of HMGCS1 triggers its ubiquitin-dependent degradation to alleviate hepatic steatosis

Mengzhou Wang, Xiaoning Wu, Tao Wang, Wuming Liu et autres

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SUMOylation-driven nuclear translocation of HSF2BP alleviates MASLD via COX6A1-dependent mitochondrial reprogramming

Mengzhou Wang, Xiaoning Wu, Tao Wang, Wuming Liu et autres

Metabolic dysfunction-associated steatotic liver disease (MASLD) remains a major global health burden with limited therapeutic options. Heat shock factor 2 binding protein (HSF2BP), originally characterized as a germ cell-specific regulator of meiosis, is significantly upregulated in both MASLD patient livers and high-fat …

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A fiber balloon catheter for uniform light delivery in intraductal photodynamic therapy of bile duct tumors

Yiwen Lu, G X Liu, Meng Zhao, Le Jiang et autres

BACKGROUND: Intraductal photodynamic therapy (PDT) is a promising minimally invasive treatment for bile duct tumors, but clinical efficacy is limited by uneven intraductal light distribution and light dose attenuation induced by intraluminal blood and bile. OBJECTIVE: To develop an optical transmission device …

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A Gd(III) dodecahedron and its surfactant-composited aggregate as enhanced contrast agents for magnetic resonance imaging

Sai‐Sai Xie, Xue-Mei Chang, Peng-Fei Sun, Xin-Yuan Wei et autres

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Milk fat globule—EGF factor 8/ATP‐binding cassette subfamily E member 1 axis maintains mitophagy flux homeostasis to suppress ferroptosis in acute pancreatitis

Yifan Ren, Yuxuan Lu, Qing Cui, Hao Shang et autres

Abstract Background Acute pancreatitis (AP) is a severe inflammatory disorder in which mitochondrial dysfunction and ferroptosis critically drive acinar cell injury. Our previous work suggested a protective role for exogenous milk fat globule—epidermal growth factor 8 (MFG‐E8) in AP. This study aimed …

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