Guancheng Xiao

Exploration of neutrophil-associated genes in the prognosis of bladder urothelial carcinoma based on a machine learning and multi-omics data integration framework

Muya Ran, Xiaoming Chen, Guancheng Xiao, 黃若惠 et autres

BACKGROUND: Bladder urothelial carcinoma (BLCA) is a prevalent malignancy. The poor performance of existing therapeutic approaches in the advanced stages of BLCA underscores the critical need for more sensitive and precise biomarkers to improve patient survival and prognosis. METHODS: This study utilized …

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Research on Key Technologies for Reconstruction and Expansion of Loose Semi-Rigid Base Asphalt Concrete Pavement

Guancheng Xiao

Some early-constructed semi-rigid base asphalt concrete pavements have severe looseness in the base layer, which makes it impractical to evaluate the fatigue life of the inorganic binder-stabilized layer for pavement reinforcement under these conditions. This kind of pavement widening project is affected …

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Anoikis in prostate cancer bone metastasis gene signatures and therapeutic implications

Wei Xia, Miao Ye, Bo Jiang, Gang G. Xu et autres

Background: Bone metastasis from prostate cancer severely impacts patient outcomes and quality of life. Anoikis, a form of programmed cell death triggered by the loss of cell-matrix interactions, plays a critical role in cancer progression. However, its precise relationship with prostate cancer-induced …

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Unusual renal displacement due to massive splenomegaly: a rare case report and review of literature

Zhihua He, Wuhao Liu, Jiafu Xiao, Guancheng Xiao

Here, the case of a female patient in her late 60s, who presented to hospital for a scheduled health check relating to a history of myelofibrosis for the previous 9 years, is described. She recently experienced weight loss and abdominal distention. Physical …

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Overexpression of DUSP26 gene suppressed the proliferation, migration, and invasion of human prostate cancer cells

Ruohui Huang, Qing-Ming Zeng, Bo Jiang, Gang Xu et autres

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Prognosis and diagnosis of prostate cancer based on hypergraph regularization sparse least partial squares regression algorithm

Ruohui Huang, Zi-Lu Ge, Gang Xu, Qing-Ming Zeng et autres

BACKGROUND: Prostate cancer (PCa) is a malignant tumor of the male reproductive system, and its incidence has increased significantly in recent years. This study aimed to further identify candidate biomarkers with prognostic and diagnostic significance by integrating gene expression and DNA methylation …

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Knockout of phosphatidylethanolamine binding protein4 ( PEBP4 ) promotes chronic non‐bacterial prostatitis by mediating the activation of NF‐κB signaling

Hailan He, Guancheng Xiao, Xing Hu, Hui Luo et autres

Abstract Background The etiology of chronic prostatitis remains unclear; consequently, this disease is associated with recurrence and ineffective clinical therapy. Therefore, there is an urgent need to investigate the underlying pathogenesis of chronic prostatitis in order to develop more efficacious treatments. Objective …

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Dual-specificity phosphatase 26 inhibits proliferation, migration, and invasion of prostate cancer via the TAK1-JNK/p38 signaling pathway

Ruohui Huang, Qing-Ming Zeng, Bo Jiang, Gang Xu et autres

Abstract As the most frequently identified malignant tumor of the male genitourinary system, prostate cancer (PCa) is threatening the health of millions of people worldwide because of its malignant, easy-to-transfer, and complicated complications. Moreover, the complex pathological mechanism of prostate cancer has …

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Correction: Knockdown of ubiquitin-like modifier-activating enzyme 2 promotes apoptosis of clear cell renal cell carcinoma cells

Guoxi Zhang, Junrong Zou, Jinglin Shi, Biao Qian et autres

Correction to: Cell Death and Disease (2021) 12:1067 https://doi.org/10.1038/s41419-021-04347-7 , published online 09 November 2021

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Multi-omics data integration analysis of prostate cancer based on sparse least partial squares regression algorithm based on hypergraph regularization

Ruohui Huang, Zi-Lu Ge, Gang Xu, Qing-Ming Zeng et autres

Abstract Prostate cancer (PCa) is a malignant tumor of the male reproductive system, and its incidence has increased significantly in recent years. This study aimed to further identify candidate biomarkers with prognostic and diagnostic significance by integrating gene expression and DNA methylation …

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Lysosomal-Associated Transmembrane Protein 5 Promotes Proliferation, Migration, and Invasion of Clear Cell Renal Cell Carcinoma

Ruohui Huang, Zi-Lu Ge, Gang Xu, Qing-Ming Zeng et autres

Clear cell renal cell carcinoma (ccRCC) is the most aggressive and deadly cancer of the urinary system and is regulated by multiple signaling pathways. However, the specific molecular mechanisms underlying ccRCC have not been fully studied or demonstrated. This study aimed to …

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MP20-02 PROTECTIVE ROLE OF METFORMIN IN ACUTE RENAL ISCHEMIC REPERFUSION INJURY

Junrong Zou, Xiaofeng Zou, Guoxi Zhang, Kecheng Lou et autres

You have accessJournal of UrologyCME1 May 2022MP20-02 PROTECTIVE ROLE OF METFORMIN IN ACUTE RENAL ISCHEMIC REPERFUSION INJURY Junrong Zou, Xiaofeng Zou, Guoxi Zhang, Kecheng Lou, Shangzhi Feng, Guancheng Xiao, and Hailan He Junrong ZouJunrong Zou More articles by this author , Xiaofeng …