Frances Borg

Ultrasonographic Halo Score in giant cell arteritis: association with intimal hyperplasia and ischaemic sight loss

Kornelis S. M. van der Geest, Konrad Wolfe, Frances Borg, Alwin Sebastian et autres

OBJECTIVES: We investigated the relationship between the ultrasonographic Halo Score and temporal artery biopsy (TAB) findings in GCA. METHODS: This is a prospective study including 90 patients suspected of having GCA. Ultrasonography of temporal/axillary arteries and a TAB were obtained in all …

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G308 Combined rheumatology and orthoptic-led screening clinics for juvenile idiopathic arthritis

SJ Perera, Anurag Shrivastava, Frances Borg, Vernon Geh

Background Uveitis in Juvenile idiopathic arthritis (JIA) is prevalent in 8–30% cases. BSPAR and the RCPOphth (2006) jointly has recommended guidelines for Screening for Uveitis (SfU) in Juvenile Idiopathic Arthritis (JIA). However, concerns with compliance with screening remain (East of England audit …

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O06 Inflammatory arthritis triggered by COVID-19

Ghazal Ansari, Frances Borg, Gouri Koduri

Abstract Case report - Introduction COVID-19 is an infectious disease caused by a newly discovered β-coronavirus, named Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), resulted in a recent pandemic of COVID-19. As a novel pathogen, the nature and degree of risk of COVID-19 to …

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Response to: ‘Diagnostic accuracy of novel ultrasonographic halo score for giant cell arteritis: methodological issues’ by Ghajari and Sabour

Kornelis S. M. van der Geest, Frances Borg, Abdul Kayani, Davy Paap et autres

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FRI0195 ULTRASONOGRAPHIC HALO SCORE ASSOCIATES WITH INTIMAL HYPERPLASIA IN GIANT CELL ARTERITIS

Kornelis S. M. van der Geest, Frances Borg, Konrad Wolfe, Wolfgang Schmidt et autres

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P16 Orthoptic led eye screening co-located within the paediatric rheumatology clinic for safer management of children with JIA

Aicha Bouraoui, Laura Roberts, Alexandra Landells, Elizabeth M. Law et autres

Abstract Background Juvenile idiopathic arthritis (JIA) affects 1 in 1000 children. Around 10% to 30% of children with JIA develop anterior uveitis. Particularly in the oligoarticular subtype, this uveitis is chronic and therefore asymptomatic, without the classical red eye and pain of …

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P42 Use of trametinib, a MEK1 inhibitor, to treat Erdheim Chester disease (ECD)

Hoda Alkoky, Talha Munir, Frances Borg

Abstract Background Erdheim Chester disease (non-Langerhan’s cell histocytosis) is a poorly recognised rare multisystem disorder. Alfa interferon (αINF) is recommended as initial therapy. BRAFV600E and MAP2K1 mutations have been identified in this condition, for which targeted biologic therapy is now available. We …

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Novel ultrasonographic Halo Score for giant cell arteritis: assessment of diagnostic accuracy and association with ocular ischaemia

Kornelis S. M. van der Geest, Frances Borg, Abdul Kayani, Davy Paap et autres

OBJECTIVES: Ultrasound of temporal and axillary arteries may reveal vessel wall inflammation in patients with giant cell arteritis (GCA). We developed a ultrasound scoring system to quantify the extent of vascular inflammation and investigated its diagnostic accuracy and association with clinical factors …

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237 Monitoring of interstitial lung disease in rheumatoid patients in routine clinical practice and therapies

Shehla Siddiqui, Fiona Coath, Anurag Bharadwaj, Frances Borg et autres

Background: Interstitial lung disease (ILD) is a progressive fibrotic disease of the lung parenchyma. ILD is the only complication of rheumatoid arthritis (RA) reported to be increasing. It accounts for 6% all RA deaths. The prognosis of patients with RA-ILD has been …

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Long-term efficacy and safety of tocilizumab in giant cell arteritis and large vessel vasculitis

Jobie Evans, Lauren Steel, Frances Borg, Bhaskar Dasgupta

Giant cell arteritis (GCA) is a chronic systemic vasculitis affecting large-sized and medium-sized vessels. Glucocorticoids are currently the mainstay of treatment for GCA and associated large vessel vasculitis (LVV) but are associated with frequent adverse events. Methotrexate has only demonstrated a modest …

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Fast track pathway reduces sight loss in giant cell arteritis: results of a longitudinal observational cohort study.

Pravin O. Patil, Mark D. Williams, Win Win Maw, Katerina Achilleos et autres

OBJECTIVES: To investigate the effectiveness of a fast track pathway (FTP) on sight loss in patients with suspected giant cell arteritis (GCA). METHODS: A longitudinal observational cohort study was conducted in the secondary care rheumatology department. One hundred and thirty-five newly referred …

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E24. Myositis Following Vaccination: An Unexpected Risk of Travel

Fiona Hayes, Asad Khan, Bernadette Lynch, Frances Borg

Background: Drug-induced myositis is well described in medical literature, with a variety of agents implicated. We describe a case following vaccination for HAV and typhoid in preparation for travel abroad; this has not previously been documented as a causative agent. The patient …

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