Hyun Seung Shin

Behavioral effects of chronic PFHxA exposure on spatial memory function

Dong Hun Lee, BaDa Cho, Jieun Seo, Yun Hee So et autres

Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants widely detected in human biological samples. As regulatory restrictions on long-chain PFAS such as PFOA and PFOS have increased, short-chain alternatives, including perfluorohexanoic acid (PFHxA) have been widely adopted due to their lower …

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Polystyrene nanoplastic-encapsulated extracellular vesicles promote blood–brain barrier breakdown and accumulate in the brain

Min Jae Kim, Hyun Seung Shin, Yun Hee So, Dong Hun Lee et autres

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Weathered plastic particles negatively affect mouse primary neurons and glial cells

Hyun Seung Shin, Yun Hee So, Dong Hun Lee, Yunsoo Chang et autres

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Stage-specific effects of nanoplastic exposure on neurodevelopment and offspring behavior

Hyun Seung Shin, Yun Hee So, Dong Hyun Lee, Min Young Kim et autres

With the continuous increase in plastic production, nanoplastics (NPs) derived from degrading plastic products have emerged as a critical environmental pollutant. NPs have been found in the human placenta and breast milk; however, the potential effects of NP exposure in various developmental …

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Ginsenoside Re mitigates Aβ1-42-induced neurotoxicity by promoting autophagy and suppressing NLRP3 inflammasome

Iskander Madhi, Hyun Seung Shin, Yun Hee So, Eui‐Man Jung et autres

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by β-amyloid (Aβ) accumulation and neuroinflammation. Activation of NOD-like receptor pyrin domain-containing 3 (NLRP3) inflammasome in microglia significantly contributes to AD-associated neuroinflammation and neuronal damage. Ginsenoside Re (G-Re), a major bioactive constituent of …

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New insights into the olfactory development disrupted by 4-tert-Octylphenol in offspring mice

Dong Hun Lee, Hyun Seung Shin, Yun Hee So, Jin Yeop Kim et autres

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Maternal exposure to 4-tert-octylphenol causes alterations in the morphology and function of microglia in the offspring mouse brain

Seung Hyun Lee, Hyun Seung Shin, Yun Hee So, Dong Hun Lee et autres

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Effects of maternal nonylphenol exposure on the proliferation of glial cells in the brain of male offspring mice

Seung Hyun Lee, Hyun Seung Shin, Yun Hee So, Dong Hun Lee et autres

Glial cells play a significant role in maintaining brain homeostasis and normal brain development, and their functions can be impaired by exposure to endocrine disruptors. 4-n-Nonylphenol (NP), a representative endocrine disruptor, is widely used in personal care products and industrial materials. NP …

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Prolonged stress response induced by chronic stress and corticosterone exposure causes adult neurogenesis inhibition and astrocyte loss in mouse hippocampus

Hyun Seung Shin, Seung Hyun Lee, Ha Jung Moon, Yun Hee So et autres

Chronic stress is a pervasive and complex issue that contributes significantly to various mental and physical health disorders. Using the previously established chronic unpredictable stress (CUS) model, which simulates human stress situations, it has been shown that chronic stress induces major depressive …

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Maternal Exposure to 4-Tert-Octylphenol Causes Alterations in the Morphology and Function of Microglia in the Offspring Mouse Brain

Seung Hyun Lee, Hyun Seung Shin, Yun Hee So, Dong Hun Lee et autres

Maternal exposure to polystyrene microplastics impairs social behavior in mouse offspring with a potential neurotoxicity

Yun Hee So, Hyun Seung Shin, Seung‐Hyun Lee, Ha Jung Moon et autres

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Effects of prenatal bisphenol S and bisphenol F exposure on behavior of offspring mice

Ha Jung Moon, Hyun Seung Shin, Seung‐Hyun Lee, Eui‐Ju Hong et autres

Bisphenol A (BPA) is a representative endocrine-disrupting chemical that exhibits hormonal disturbance reactions. Various alternatives, such as Bisphenol S (BPS) and Bisphenol F (BPF), are being developed. BPS and BPF (which are representative alternatives to BPA) are used in consumer products such …

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