Nazia Tabassum Iqbal

Clinical spectrum and outcomes of autoimmune hepatitis in children: a quaternary centre experience

Nazia Tabassum Iqbal, Iqtadar Seerat, Sobia Noureen, Hassan Bashir

OBJECTIVE: To analyse paediatric autoimmune hepatitis with respect to disease severity, treatment response, and clinical outcomes, including progression to liver failure and transplant survival. Methods: The retro-prospective study was conducted at the Pakistan Kidney and Liver Institute and Research Centre, Lahore, Pakistan, …

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Risk factors of pleural effusion in post-liver transplant pediatric population

Muhammad Saqib, Nazia Tabassum Iqbal, Ahmad Saqib, Safia Khan

Background and Objective: Pediatric liver transplantation (LT) is curative therapy for end-stage liver disease. One of the most frequent pulmonary complications after LT in children is pleural effusion. With improvement in surgical techniques and postoperative intensive care, long-term survival is now more …

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Therapeutic Plasma Exchange in Tandem With Other Types of Extracorporeal Circuits: The Experience of a Pediatric Center and a Review of Other Pediatric Center Reports

Lejla Music Aplenc, Nicole M. Wood, Nazia Tabassum Iqbal, Cindy George et autres

Therapeutic plasma exchange (TPE) concurrently performed in critically ill pediatric patients with other extracorporeal circuits is a complex process. We sought to characterize tandem procedures, including patient demographics, primary diagnosis, American Society for Apheresis (ASFA) category indications, survival at 24 h and …

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Pulmonary Embolism: A Rare Presentation of Acute-on-Chronic Pancreatitis in Children

Nazia Tabassum Iqbal, Maryam Mazhar, Sobia Noureen, Eman Shujaat et autres

Although splanchnic vein thrombosis may manifest as pancreatitis, it is rare to find venous thrombosis at other body sites. We present a rare case of acute-on-chronic pancreatitis in a patient who subsequently developed a deep venous thrombosis (DVT) of the right lower …

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Clinical Manifestations and Outcomes of Budd-Chiari Syndrome in Children: A Single-Centre Study

Hassan Bashir, Maryam Mazhar, Iqtadar Seerat, Nazia Tabassum Iqbal et autres

Introduction Budd-Chiari syndrome (BCS) is a rare cause of ascites in children, and its clinical manifestation depends upon the extent and rapidity of the occlusion of hepatic veins. This study aimed to identify the clinical manifestations, causes, treatment options, and outcomes of …

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Evidence that donors with variant RH genotypes are associated with unexpected Rh antibodies

Julie Kirkegaard, Lynsi Rahorst, Anna Burgos, Lejla Music Aplenc et autres

BACKGROUND: We previously reported unexpected Rh antibodies in the plasma of patients with sickle cell disease (SCD) that demonstrated common Rh specificities in the absence of transfusion of RBCs positive for that antigen. We hypothesize that these antibodies might result from transfusion …

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Therapeutic plasma exchange for multiorgan dysfunction among critically ill pediatric patients with leukemia: A single‐institutional experience

Sarah Mc Dermott, Chandni Dargan, Elizabeth González Domínguez, Lejla Music Aplenc et autres

INTRODUCTION: Therapeutic plasma exchange (TPE) has well-documented applications in the adult population, outlined by the American Society for Apheresis (ASFA) 2019 guidelines. Limited data exist regarding the use of TPE in critically ill pediatric patients; however, these reports rarely include patients with …

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Pay attention to neutrophil inclusions in pediatric patients with thrombocytopenia

Nazia Tabassum Iqbal, Weijie Li

![Figure][1] A 12-month-old previously healthy boy with a recent history of viral infection was found to have worsening thrombocytopenia (platelet count, 21-78 × 109/L). Immature platelet fraction was 51% (reference range: 0-7%). Red blood cells and white blood cells were within normal

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Clinical and molecular characterization of novel deletions causing epsilon gamma delta beta thalassemia: Report of two cases

Elena A. Repnikova, Jennifer Roberts, Sarah Mc Dermott, Midhat S. Farooqi et autres

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Reactive germinal centers in the bone marrow of an infant with autoimmune neutropenia

Weijie Li, Nazia Tabassum Iqbal

![Figure][1] An 11-month-old boy presented with history of recurrent fever for a few months, and was found to have neutropenia (neutrophil count 0.16 × 109/L), mild anemia (hemoglobin 11 g/dL), and normal platelet count (376 × 109/L). Granulocyte immunofluorescence test was positive. …

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