Infectious Disease Management in Resource-Limited Settings
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Abstract
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Gabriela Garrido-Pinzas, Brian Valenzuela, Elsa González-Lagos, Carlos Seas et autres
BACKGROUND: Adult T-cell Leukemia/Lymphoma (ATL) is caused by human T-leukemia virus type 1 (HTLV-1). Over 10 million people are infected worldwide, but only up to 5% develop ATL. HTLV-1 infection is endemic in Peru; however, there are currently no reports focusing on …
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Eduardo Gotuzzo, D. Martinez, Blas M Cornejo-Esparza, Daniel Guillen et autres
Abstract Background Balamuthia mandrillaris is a neglected free-living ameba causing cutaneous lesions and granulomatous encephalitis with high mortality. Diagnostic testing is limited, and cases may be underdiagnosed and underreported. A low threshold of clinical suspicion should prompt workup and treatment. Miltefosine was …
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Yosué I Vera, Nicolás Zamudio, P E D R O E LEGUA, Dany J RIVERA CRUZADO et autres
Abstract Background The global prevalence of cancer has increased in recent decades. Cancer patients are particularly susceptible to invasive infections such as bacteremia. In Peru, the rising incidence of bloodstream infections caused by resistant pathogens represents a significant public health concern. However, …
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Carlos Acuña-Villaorduña, Anna Vassall, Germán Henostroza, Carlos Seas et autres
Background: Resistance to commonly used anti-tuberculosis (TB) drugs is emerging worldwide. Conventional drug susceptibility tests (DST) are slow and demanding. Alternative, rapid DST methods would permit the early detection of drug resistance and in turn arrest TB transmission. Methods: A cost-effectiveness analysis …
Sebastian Alcalde Ochoa, Milagros Quispe-Mendoza, Jim Valenzuela Medina, Carlos McFarlane et autres
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A 29-year-old male farmer from Yambrasbamba, Amazonas, in the Amazon rainforest in Peru presented with a 4-month history of cervical lymphadenopathy, persistent fever, jaundice, weight loss, abdominal pain, and malaise. Physical examination revealed multiple mobile and painless lymph nodes in the submental, …
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Nicolas Barros, César Augusto Sánchez, A. Clinton White, Allison Bauer et autres
Background: Combination antiretroviral therapy (cART) can suppress human immunodeficiency virus (HIV-1) replication, but some patients develop worsening of co-infections, termed immune reconstitution inflammatory syndrome. Regulatory T cells (Tregs) are a population of CD4+ T cells that modulate immune responses. We hypothesized that …
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Rodrigo Cachay, Takashi Watanabe-Tejada, Katiuska Cuno, Marcela Gil-Zacarías et autres
INTRODUCTION: The sequelae of COVID-19 have been described as a multisystemic condition, with a great impact on the cardiovascular and pulmonary systems with abnormalities in pulmonary function tests, such as lower diffusing capacity of the lung for carbon monoxide (DLco) levels and …
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