Linqiu Cao

Metabolic diversity and competitive interactions of infant-derived bifidobacteria in human milk oligosaccharides and galacto-oligosaccharide utilization

Shaojun He, Chun Chen, Linqiu Cao, Arjen Nauta et autres

Human milk oligosaccharides (HMO) play a pivotal role in shaping the infant gut microbiome and immune system, primarily by selectively promoting Bifidobacterium species. Although the metabolic pathways of individual bifidobacterial strains for HMO are well-characterized, competitive interactions among multiple strains under single-HMO …

cn, nl (code pays fourni par la source)

Gram-scale chemical synthesis of galactosyllactoses and their impact on infant gut microbiota in vitro

Evy Meeusen, Linqiu Cao, Dianne J. M. Delsing, André Groeneveld et autres

We report the gram-scale chemical synthesis of 3′-, 4′-, and 6′-galactosyllactose starting from lactose. The impact of these galactosyllactoses on infant gut microbiota was tested in vitro by fermentation experiments using infant faecal samples.

nl (code pays fourni par la source)

High purity galacto-oligosaccharides: Optimal process design and prebiotic effect

Linqiu Cao, Miranda Bultsma, Jeroen Wissing, Beatrix Gerhard et autres

Prebiotic unpurified commercial galacto-oligosaccharides (GOS) often contain significant amounts of glucose, galactose and lactose. Current purification processes remove these digestible components, especially lactose with a high risk of affecting functionality. In the current study a high purity GOS (HP-GOS) was prepared by …

nl, de (code pays fourni par la source)

Bifidobacterial β-Galactosidase-Mediated Production of Galacto-Oligosaccharides: Structural and Preliminary Functional Assessments

Valentina Ambrogi, Francesca Bottacini, John A. MacSharry, Justin van Breen et autres

In the current study the ability of four previously characterized bifidobacterial β-galactosidases (designated here as BgaA, BgaC, BgaD, and BgaE) to produce galacto-oligosaccharides (GOS) was optimized. Of these enzymes, BgaA and BgaE were found to be promising candidates for GOS production (and …

ie, nl, es (code pays fourni par la source)

Galacto-oligosaccharides as infant prebiotics: production, application, bioactive activities and future perspectives

Valentina Ambrogi, Francesca Bottacini, Linqiu Cao, Bas J.H. Kuipers et autres

Galacto-oligosaccharides (GOS) are non-digestible oligosaccharides characterized by a mix of structures that vary in their degree of polymerization (DP) and glycosidic linkage between the galactose moieties or between galactose and glucose. They have enjoyed extensive scientific scrutiny, and their health-promoting effects are …

ie, nl (code pays fourni par la source)

Infant-Associated Bifidobacterial β-Galactosidases and Their Ability to Synthesize Galacto-Oligosaccharides

Valentina Ambrogi, Francesca Bottacini, John A. O'Callaghan, Eoghan Casey et autres

Galacto-oligosaccharides (GOS) represent non-digestible glycans that are commercially produced by transgalactosylation of lactose, and that are widely used as functional food ingredients in prebiotic formulations, in particular in infant nutrition. GOS consumption has been reported to enhance growth of specific bacteria in …

ie, nl (code pays fourni par la source)

Characterization of GH2 and GH42 β-galactosidases derived from bifidobacterial infant isolates

Valentina Ambrogi, Francesca Bottacini, Joyce O’Sullivan, Mary O’Connell Motherway et autres

Bifidobacteria are among the first and most abundant bacterial colonizers of the gastrointestinal tract of (breast-fed) healthy infants. Their success of colonising the infant gut is believed to be, at least partly, due to their ability to metabolize available carbon sources by …

ie, nl (code pays fourni par la source)

Modular synthesis and immunological evaluation of suspected allergenic galactooligosaccharides

Hidde Elferink, Emiel Rossing, Chiung‐Hui Huang, Bee Wah Lee et autres

Galactooligosaccharides (GOS) are widely used in the food industry as prebiotics and in very rare cases, can lead to an allergic reaction. Due to the microheterogeneity of GOS it is very difficult to extract pure and well defined oligosaccharides to establish which …

nl, ca, kr, sg (code pays fourni par la source)

Enzyme immobilisation: fundamentals and application

Ulf Hanefeld, Linqiu Cao, Edmond Magner

A graphical abstract is available for this content

nl, ie (code pays fourni par la source)

Immobilized Enzymes

Linqiu Cao

nl (code pays fourni par la source)

Carrier-bound Immobilized Enzymes: Principles, Application and Design

Linqiu Cao

Foreword. 1. Introduction: Immobilized Enzymes: Past, Present and Prospects. 2. Adsorption-based Immobilization. 3. Covalent Enzyme Immobilization. 4. Enzyme Entrapment. 5. Enzyme Encapsulation. 6. Unconventional Enzyme Immobilization. Subject Index.

Adsorption‐based Immobilization

Linqiu Cao

This chapter contains sections titled: Introduction Classification of Adsorption Principles Involved in Absorptive Enzyme Immobilization Monolayer Principle Stabilization Principle Enzyme Distribution Requirement of the Carriers Physical Requirements Pore-size and Available Surface Internal Structure Density of Binding Functionality Particle Size Chemical Nature of …